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Global relationships between crop diversity and nutritional stability

Nutritional stability – a food system’s capacity to provide sufficient nutrients despite disturbance – is an important, yet challenging to measure outcome of diversified agriculture. Using 55 years of data across 184 countries, we assemble 22,000 bipartite crop-nutrient networks to quantify nutritional stability by simulating crop and nutrient loss in a country, and assess its relationship to crop

Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer

Splicing is a central RNA-based process commonly altered in human cancers; however, how spliceosomal components are co-opted during tumorigenesis remains poorly defined. Here we unravel the core splice factor SF3A3 at the nexus of a translation-based program that rewires splicing during malignant transformation. Upon MYC hyperactivation, SF3A3 levels are modulated translationally through an RNA st

Facial hair shaving behavior and skin problems of shaved areas of males

Unwanted facial hair is a common problem and requires different grooming regimens or treatments. Shaving beard hair can cause undesirable skin effects, such as irritation, razor burn, razor nick, and pseudofolliculitis barbae. This study explores male behaviors related to shaving facial hair and the consequential effects on the shaved skin. A questionnaire-based, cross-sectional, analytical study

Liver resection and ablation for squamous cell carcinoma liver metastases

BACKGROUND: Limited evidence exists to guide the management of patients with liver metastases from squamous cell carcinoma (SCC). The aim of this retrospective multicentre cohort study was to describe patterns of disease recurrence after liver resection/ablation for SCC liver metastases and factors associated with recurrence-free survival (RFS) and overall survival (OS). METHOD: Members of the Eur

Opportunities and challenges of high‐pressure fast pyrolysis of biomass : A review

Most pyrolysis reactors require small sizes of biomass particles to achieve high‐quality products. Moreover, understanding the usefulness of high‐pressure systems in pyrolysis is important, given the operational challenges they exhibit specific to various biomass materials. To actualize these aspects, the authors first checked previous reviews involving pyrolysis on different biomass and different

Efficacy of mepolizumab in usual clinical practice and characteristics of responders : Mepolizumab in usual clinical practice

Background: Severe eosinophilic asthma is a high-burden disease. Mepolizumab has been effective in several randomized clinical trials. However, such success might not be applicable to patients treated in usual clinical practice. The objectives of this article are to evaluate the efficacy of mepolizumab in severe uncontrolled eosinophilic asthma under usual clinical practice, and to determine chara

Neurofeedback Rehabilitation Reduces Anxiety in Methamphetamine Abusers

Addictive disorders are characterized by cognitive, behavioral, and neurological impairments caused by dysregulations of brain structure that can extend well beyond early withdrawal in the months and years of recovery. The present study aimed to examine the efficacy of neurofeedback rehabilitation on anxiety in methamphetamine abusers. The sample consisted of 14 male methamphetamine drug addicts w

Modeling Nonlinear Dendritic Processing of Facilitation in a Dragonfly Target-Tracking Neuron

Dragonflies are highly skilled and successful aerial predators that are even capable of selectively attending to one target within a swarm. Detection and tracking of prey is likely to be driven by small target motion detector (STMD) neurons identified from several insect groups. Prior work has shown that dragonfly STMD responses are facilitated by targets moving on a continuous path, enhancing the

Bergman and the business : Notes on the director’s ‘worth in the market’

This chapter discusses Bergman’s potential worth in the commercial film market on the basis of the director’s own correspondence with potential co-producers and international distributors of his films. The author first studies Bergman’s ample correspondence with Carl Anders Dymling, the powerful head of the Swedish production company Svensk Filmindustri between 1942 and 1961; most of Bergman’s ear

Mobility and muscle strength trajectories in old age : the beneficial effect of Mediterranean diet in combination with physical activity and social support

Introduction: Decline in physical function varies substantially across older individuals due to several extrinsic modifiable factors such as dietary patterns, physical activity and social support. We aimed to determine the association of these factors and their interaction with mobility and muscle strength decline. Methods: We analyzed data from 1686 functionally healthy individuals aged 60 + from

Modelling and controlling of polymer electrolyte fuel cell systems

This thesis focuses on the modelling and controlling of polymer electrolyte fuelcell (PEFC) systems. A system level dynamic PEFC model has been developedto test the system performance (output voltage, reactants gas partial pressures,and stack temperature) for different operating conditions. The simulation resultsare in good agreement with the experimental data, which indicates that thePEFC model i