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Observer-Based Strict Positive Real (SPR) Feedback Control System Design

This paper presents theory for stability analysis and design for a class of observer-based feedback control systems. Relaxation of the controllability and observability conditions imposed in the Yakubovich-Kalman-Popov (YKP) lemma can be made for a class of nonlinear systems described by a linear time-invariant system (LTI) with a feedback-connected cone-bounded nonlinear element. It is shown how

A Fast Physical NOx Model Implemented on an Embedded System

This paper offers a two-zone, physical, NOx model with low computational cost, implemented in C on an embedded system. The model is able to compute NOx-emission formation with high time resolution during an engine cycle. To do this the model takes cylinder pressure and injected fuel amount as inputs and produces NO concentration as output. The model as such is not new, nevertheless the physical ba

Method for Programming Differentiated Cells into Hematopoietic Stem Cells

The disclosure relates to the development of methods for making hematopoietic stem cells from differentiated cells by introducing and expressing transcription factors. More particularly, the disclosure provides methods for redirecting differentiated cells to a hematopoietic stem cell state or to a hemogenic endothelial cell state by direct programming with specific combinations of transcription fa

Changes in P2Y6 receptor-mediated vasoreactivity following focal and global ischemia

Ischemia, both in the form of focal thromboembolic stroke and following subarachnoid hemorrhage (SAH), causes upregulation of vasoconstrictive receptor systems within the cerebral vasculature. Descriptions regarding changes in purinergic signaling following ischemia are lacking, especially when the importance of purinergic signaling in regulating vascular tone is taken into consideration. This pro

“Black race”, “Schwarze Hautfarbe”, “Origine africaine”, or “Etnia nera”? The absent presence of race in European pharmaceutical regulation

Current scholarship on race in Europe has described race as an “absent presence”. However, little is known about the dynamics of the absentness and presentness of race, including how various social processes operating at distinct levels (e.g., supranational and national) influence the uses of race and ethnicity concepts. We begin addressing this gap by examining racialised pharmaceutical regulatio

Technical requirements for the implementation of an experience base

Reuse of different types of experience is a key issue in successful improvement in software engineering. The approach taken in the Quality Improvement Paradigm (QIP) and its supporting organisation, tile Experience Factory (EF), is to define an Experience Base (EB), where all types of reusable objects are organised and stored. The objects may be of any type related to software development, for exa

An evaluation of functional size methods and a bespoke estimation method for real-time systems

Functional size, or function points, is a language-independent measure of software size. It is used as an estimator of development effort and software code size, in particular in the domain of information systems, while in real-time systems it is not so widely spread. In this paper, functional size measurements are empirically evaluated by applying them to a recently completed project. Two establi

Agricultural Productivity in Burkina Faso: The Role of Gender and Risk Attitudes

This study analyzes how risk attitudes influence the agricultural productivity of men and women in a sub- Saharan African country, Burkina Faso. By using a large representative panel survey of farmers, the results show that as female farmers increase risk taking, the productivity of female-owned plots goes down. The study controls for various socio-economic factors and explores how the diversity oThis study analyzes how risk attitudes influence the agricultural productivity of men and women in a sub- Saharan African country, Burkina Faso. By using a large representative panel survey of farmers, the results show that as female farmers increase risk taking, the productivity of female-owned plots goes down. The study controls for various socio-economic factors and explores how the diversity o

Assemblage-democracy : Reconceptualising democracy through material resource governance

This article furthers political geographic thinking on democracy by generating and employing a conceptualisation of ‘assemblage-democracy’. Bringing an assemblage perspective to democratic thinking brings to the fore three key dimensions: the co-constitution of material and non-material connections; connectivity and associations, in particular engagement with multiple heterogeneous ‘minoritarian’

Decarbonizing capital : Investment, divestment and the qualification of carbon assets

Private investment capital is now widely regarded as strategically significant to the governance of climate change. A dedicated and dynamic carbon finance sector has emerged that features techniques and practices for decarbonizing capital, facilitating investment in low-carbon projects and enterprises or enabling divestment from high-carbon firms and sectors. We bring together and develop the conc

Solving Exact Cover Instances with Molecular-Motor-Powered Network-Based Biocomputation

Information processing by traditional, serial electronic processors consumes an ever-increasing part of the global electricity supply. An alternative, highly energy efficient, parallel computing paradigm is network-based biocomputation (NBC). In NBC a given combinatorial problem is encoded into a nanofabricated, modular network. Parallel exploration of the network by a very large number of indepen

REM-Predominant Obstructive Sleep Apnea in Patients with Coronary Artery Disease

Obstructive sleep apnea (OSA) is common in adults with coronary artery disease (CAD). OSA that occurs predominantly during rapid-eye movement (REM) sleep has been identified as a specific phenotype (REM-predominant OSA) in sleep clinic cohorts. We aimed to examine the association of REM-predominant OSA with excessive sleepiness, functional outcomes, mood, and quality of life in a CAD cohort, of wh

Introduction : Rigour and relevance in European entrepreneurship research

This introduction provides an overview and commentary on the main chapters in the book. The book presents contemporary examples of European research that embrace both rigour and relevance. In doing so, the book demonstrates that both rigour and relevance is alive in entrepreneurship research. Many of the following chapters address agendas that are influenced by pragmatic questions as much as theor