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Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products
A new fragrance mix (FM II), with 6 frequently used chemicals not present in the currently used fragrance mix (FM I), was evaluated in 6 dermatological centres in Europe, as previously reported. In this publication, test results with the individual constituents and after repeated open application test (ROAT) of FM II are described. Furthermore, cosmetic products which had caused a contact dermatit
Revision of the Botanophila helviana species group (Diptera: Anthomyiidae) in Europe
Species of the Botanophila helviana species group are small, blackish anthomyiids known from temperate to subarctic (northern/elevated) parts of the Holarctic Region. Adult flies are anthophilous, obtaining pollen and nectar from various flowering plants. Preliminary evidence suggests that the larvae may attack developing seed heads of Ranunculus (Ranunculaceae). The male and female terminalia are
The geochemistry of the Sorvik granite - a TIB-1 granite
The Sorvik granite occurs as rounded massifs in the Revsund granite in central Sweden. The rock is medium-grained with rounded quartz crystals ('drop quartz') and occasional, sometimes albiterimmed megacrysts of K-feldspar. It is a faintly peraluminous 1-type granite with some A-type affinities showing a limited chemical variation. The SiO2 content normally varies between 68 and 77 weight%. The ro
Reductive openings of acetals: Explanation of regioselectivity in borane reductions by mechanistic studies
The mechanisms of regioselective reductive openings of acetals were investigated in several model systems by a combination of Hammett plots, kinetic experiments, density functional calculations, and B-11 NMR. The regioselectivity of borane reductions of cyclic acetals can be controlled by the choice of borane. Lewis acid activation of BH3 center dot NMe3 increases the reaction rate and renders the
How people with rheumatoid arthritis perceive leisure activities: a qualitative study.
Accuracy in multiangle light scattering measurements for molar mass and radius estimations. Model calculations and experiments.
Multiangle light scattering (MALS) is a well-established technique used to determine the size of macromolecules and particles. In this study, different extrapolation procedures used in MALS were investigated with regard to accuracy and robustness in the obtained molar mass and rms radius. Three different mathematical transformations of the light scattering function referred to as the Debye, Zimm,
Chewing and the dimension of the pharyngoesophageal segment
Masticatory efficiency was evaluated in 21 adults for four chewing parameters: mixing of a color-patterned chewing gum mass, shaping of a chewing gum mass, particle reduction of a silicone tablet, and number of chewing strokes before the first swallow of an almond. The results of these tests were correlated with the dimension of the pharyngoesophageal (PE) segment during swallow of liquid barium a
Mesoscopic fluctuations of the pairing gap
A description of mesoscopic fluctuations of the pairing gap in finite-sized quantum systems based on periodic orbit theory is presented. The size of the fluctuations are found to depend on quite general properties. We distinguish between systems where corresponding classical motion is regular or chaotic, and describe in detail fluctuations of the BCS gap as a function of the size of the system. Th
Liposarcoma: a population-based epidemiologic and prognostic study of features of 43 patients, including tumor DNA content
Different conceptions exist regarding the epidemiology and prognosis of liposarcoma, and several classification systems are in use. We analyzed a population-based, 25-year series of 43 patients with liposarcoma of the extremity or trunk wall. Follow-up was complete. The annual incidence was 0.12/10(5). The thigh was the most common location. One of 6 tumors was subcutaneous. Deep-seated tumors wer
Formation of Short-Lived Protein Aggregates Directly from the Coil in Two-State Folding
Recent results on the 102 residue protein U1A show that protein aggregation is not always slow and irreversible but may take place transiently in refolding studies on a millisecond time scale. In this study we observe a similar aggregation behavior with the classical two-state protein CI2. Since both U1A and CI2 appear to fold directly from the coil at low protein concentrations, it is likely that
The impact of glycosylation on HLA-DR1-restricted T cell recognition of type II collagen in a mouse model
Objective. Type 11 collagen (01) is a candidate autoantigen implicated in the pathogenesis of rheumatoid arthritis (RA). Posttranslational glycosylation of CII could alter intracellular antigen processing, leading to the development of autoimmune T cell responses. To address this possibility, we studied the intracellular processing of CII for presentation of the arthritogenic glycosylated epitope
More efficient estimation of plant biomass
Question: The optimal use of the point intercept method (PIM) for efficient estimation of plant biomass has not been addressed although PIM is a commonly used method in vegetation analysis. In this study we compare results achieved using PIM at a range of efforts, we assess a method for calculating these results that are new with PIM and we provide a formula for planning the optimal use of PIM. Lo
Inhibiting complement regulators in cancer immunotherapy with bispecific mAbs.
Psychosocial factors, lifestyle, and fetal growth - The added value of both pre- and post-natal assessments
Background: Psychosocial resources as well as lifestyle habits during pregnancy have been shown to effect the risk of having a small-for-gestational-age (SGA) child. Most previous studies are based on a single assessment of these exposures, which does not take into account the possibility of different effects during early add late stages of pregnancy. Methods: The impact of psychosocial and lifest
Strategies for the introduction of human papillomavirus vaccination: modelling the optimum age- and sex-specific pattern of vaccination in Finland
Phase III trials have demonstrated the efficacy of human papillomavirus (HPV) vaccines in preventing transient and persistent high-risk (hr) HPV infection and precancerous lesions. A mathematical model of HPV type 16 infection and progression to cervical cancer, parameterised to represent the infection in Finland, was used to explore the optimal age at vaccination and pattern of vaccine introducti
One World Archaeology Today.
A commentary about the meaning of "One World Archaeology" today and the future of the World Archaeological Congress (WAC).
Osteoporosis and the global competition for health care resources
Global aging superimposed on existing infectious diseases and trauma will aggravate competition for health care resources to diagnose and treat osteoporosis. Efforts to implement public health measures are needed, but the targeted approach to assessment and treatment of high-risk individuals must also be refined.