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The CD40 Receptor - Target,Tool and Technology

Popular Abstract in Swedish Vårt immunförsvar arbetar konstant med att skydda kroppen från olika föremål, t. ex. bakterier, virus, gifter och cancertumörer, som kan orsaka skada eller sjukdom. För att kunna försvara kroppen mot sådana föremål så har immunförsvaret tillgång till flera, oerhört effektiva, vapen. Det viktigt att immunförsvaret känner igen, och endast angriper, skadliga föremål, så atCD40 is a cell surface receptor of pivotal importance that is expressed on several of the cells in the immune system. It is critical for many important events, such as T cell dependent B cell activation, isotype switching, somatic mutation and generation of B cell memory. The central role of CD40 in the immune system makes it an ideal target for antibody based immunotherapy. This led us to charact

Continuous-Time Identification of SISO Systems using Laguerre Functions

This paper looks at the problem of estimating the coefficients of a continuous-time transfer function given samples of its input and output data. We first prove that any nth-order continuous-time transfer function can be written as a fraction of the form /spl Sigma//sub k=0//sup n/b~/sub k/L/sub k/(s)//spl Sigma//sub k=0//sup n/a~/sub k/L/sub k/(s), where L/sub k/(s) denotes the continuous-time La

Effect of Turbulence on HCCI Combustion

This paper presents large eddy simulation (LES) and experimental studies of the combustion process of ethanol/air mixture in an experimental optical HCCI engine. The fuel is injected to the intake port manifolds to generate uniform fuel/air mixture in the cylinder. Two different piston shapes, one with a flat disc and one with a square bowl, were employed to generate different in-cylinder turbulen