BACKGROUND: The value of CT at the time of diagnosis for patients with cutaneous head and neck melanoma clinically asymptomatic for metastatic disease is unclear. METHODS: A retrospective medical chart review was performed on 198 consecutive patients identified with primary T1b-T4b head and neck melanoma clinically asymptomatic for metastatic disease referred for sentinel lymph node biopsy proceduBACKGROUND: The value of CT at the time of diagnosis for patients with cutaneous head and neck melanoma clinically asymptomatic for metastatic disease is unclear.METHODS: A retrospective medical chart review was performed on 198 consecutive patients identified with primary T1b-T4b head and neck melanoma clinically asymptomatic for metastatic disease referred for sentinel lymph node biopsy procedur

Objective: A pay for performance programme was introduced in 2009 by a Swedish county with 1.6 million inhabitants. A process measure with payment linked to coding for medication reviews among the elderly was adopted. We assessed the association with inappropriate medication for five years after baseline.Design and setting: Observational study that compared medication for elderly patients enrolled

Myndigheten för vård- och omsorgsanalys (Vårdanalys) har vänt sig till professor Anders Anell vid Lunds universitet för att genomföra fallstudier av primärvården i fyra länder: Danmark, Norge, Nederländerna och Storbritannien. Denna promemoria är hans redovisning av arbetet och är ett underlag till Vårdanalys rapport En primär angelägenhet. Kunskapsunderlag för en stärkt primärvård med patienten i

Social interactions are rarely random. In some instances, animals exhibit homophily or heterophily, the tendency to interact with similar or dissimilar conspecifics, respectively. Genetic homophily and heterophily influence the evolutionary dynamics of populations, because they potentially affect sexual and social selection. Here, we investigate the link between social interactions and allele freq

BACKGROUND: The 65-kD isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes. We hypothesized that alum-formulated GAD65 (GAD-alum) can preserve beta-cell function in patients with recent-onset type 1 diabetes. METHODS: We studied 334 patients, 10 to 20 years of age, with type 1 diabetes, fasting C-peptide levels of more than 0.3 ng per milliliter (0.1 nmol per li

In order to understand the ecological effects of climate change it is essential to forecast suitable areas for species in the future. However, species' ability to reach potentially suitable areas is also critical for species survival. These 'range-shift' abilities can be studied using life-history traits related to four range-shift stages: emigration, movement, establishment, and proliferation. He

In this paper, we introduce the concept of spatially coupled turbo-like codes (SC-TCs) as the spatial coupling of a number of turbo-like code ensembles. In particular, we consider the spatial coupling of parallel concatenated codes, introduced by Berrou et al., and that of serially concatenated codes (SCCs), introduced by Benedetto et al. Furthermore, we propose two extensions of braided convoluti

This paper aims to contribute to the knowledge on how the concept of ‘collaboration’ is being produced and reproduced – and filled with meaning – as it is articulated in news content and opinion articles about the organisation of knowledge production within higher education in Sweden. We build on a textual analysis on the public discussion in the aftermath of the announcement of the research polic

This dissertation acknowledges that accountability of educators for the grades they assign is a part of the foundation for a meritocratic society, based on fairness in judging merit and, therefore, in assigning grades. In this view, any grade obtained by any student must be both reliable and valid. This, in turn, implies that the process of assessment of students’ work on which the grade is based

Brain pericytes not only maintain the anatomical, biochemical and immune blood-brain barrier, but display features of mesenchymal stem cells (MSCs) in vitro. MSCs have pro-regenerative properties attributed to their secretome. However, whether also brain pericytes possess such pro-regenerative capacities is largely unknown. Here we characterize the secretome and microvesicle (MV) release of human