Aims Immediate treatment with a loading dose of clopidogrel at diagnosis of ST-segment elevation myocardial infarction (STEMI) is recommended by ESC/AHA/ACC guidelines in patients eligible for primary percutaneous coronary intervention (PCI). However, the evidence for this practice is scarce. Methods and results All patients who underwent PCI for STEMI in Sweden between 2003 and 2008 were identifi

Binding of platelet-derived growth factor (PDGF) to its receptors leads to the activation of members of the Src family of protein tyrosine kinases. We show here that Fyn, a member of the Src family, is phosphorylated on Tyr28 in the unique N-terminal part of the molecule after interaction with the intracellular domain of the PDGF beta-receptor. Activated Fyn furthermore undergoes autophosphorylati

This dissertation is concerned with the empirical and theoretical aspects of polarity item licensing in Swedish. I argue that polarity items are semantically sensitive to evaluability, a concept that refers to the possibility of accepting or rejecting a clause as true in a communicative exchange. Clauses are either evaluable or non-evaluable. According to the present hypothesis, non-evaluable clau

The Flinders Sensitive Line (FSL) rat is a genetic animal model of depression that displays characteristics similar to those of depressed patients including lower body weight, decreased appetite and reduced REM sleep latency. Hypothalamic neuropeptides such as orexin/hypocretin, melanin-concentrating hormone (MCH) and cocaine and amphetamine regulated transcript (CART), that are involved in the re

Reviews the video, This one moment: Skills for everyday mindfulness by M. M. Linehan (2003). Marsha Linehan is well known as the developer of Dialectical Behavior Therapy (DBT), a comprehensive treatment for borderline personality disorder (BPD). In "This One Moment," Linehan explains, with easy-to-follow and creative examples, how to be more fully in the present. She divides her instructions into

Overview over some recurrent themes in the poetry of Swedish writer Lars Gustafsson

BACKGROUND: Both chronic obstructive pulmonary disease (COPD) and tuberculosis (TB) primarily affect the lungs and are major causes of morbidity and mortality worldwide. COPD and TB have common risk factors such as smoking, low socioeconomic status and dysregulation of host defence functions. COPD is a prevalent co-morbid condition, especially in elderly with TB but in contrast to other diseases k

Depression and anxiety disorders are increasing among the general population in the Western world. Individuals may need several kinds of treatment in order to maintain health, such as cognitive behavioural therapy (CBT) and drug treatment. However, having an everyday life that "works" is also important, suggesting a need for interventions based on activities that facilitate a satisfying everyday l

Data are reported on atmospheric mercury flux measured by a lidar system at a chlor-alkali plant located in central Italy. Two mercury sources were identified over the electrolytic cell rooms. A flux value of 36 g h-1 was determined during the daytime while at night the value increase to 56 g h-1. The mercury emitted into the atmosphere was found to be 4 g per 1000 kg of chlorine produced. Atmosph

In. this study, particle image velocimetry (PIV) is used to investigate the physical process of separated flow in a square channel roughened with periodically transverse ribs on one wall. The ribs obstruct the channel by 15% of its height and are arranged 12 rib heights apart. The Reynolds number based on the bulk-mean velocity and the corresponding hydraulic diameter of the channel, is fixed at 2

A prevailing question in phytoplankton research addresses changes of genetic diversity in the face of huge population sizes and apparently unlimited dispersal capabilities. We investigated population genetic structure of the pennate planktonic marine diatom Pseudo-nitzschia multistriata at the LTER station MareChiara in the Gulf of Naples (Italy) over four consecutive years and explored possible c

Abul-Kasim K, Brizzi M, Petersson J. Hyperdense middle cerebral artery sign is an ominous prognostic marker despite optimal workflow. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2009.01277.x. (c) 2009 The Authors Journal compilation (c) 2009 Blackwell Munksgaard.Objectives - To evaluate the association between the hyperdense middle cerebral artery sign (HMCAS) and the functional outcome on one han