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Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains one of the deadliest infectious diseases worldwide. In 2023, it accounted for approximately 1.25 million deaths, including 161,000 among individuals living with HIV, making it the leading cause of death from a single infectious agent. The growing prevalence of multidrug-resistant TB (MDR-TB) further complicates treatment and contribu
A substantial external force transmitted to the brain may cause a severe traumatic brain injury (sTBI) , resulting in structural brain damage and/or functional impairment. Despite progress in management, traumatic brain injury remains a major cause of severe disability and death. This thesis evaluates treatment strategies and novel interventions in children and adults with sTBI and comprises the f
We build on the predictive processing framework to show that intelligent behaviour is adaptive control, driven by accurate prediction and uncertainty reduction in dynamic environments with limited information. We argue that adaptive control arises through a process of re-concretisation, where learned abstractions are grounded in new situations via embodiment. We use this as an explanation of why A
Mitochondria are most known as producers of ATP and for their metabolic functions in eukaryotic cells. However, these are not the only roles of these organelles, as they also have the means to communicate with the nucleus. These signals going from mitochondria to the cell nucleus are termed mitochondrial retrograde signaling or regulation (MRR). In Arabidopsis thaliana, the master regulator of MRR
Sloth moths are highly-specialized for a life in a very close relationship with sloths – the adults live in the sloth fur and the larvae feed on the sloth faeces. They belong to the pyralid subfamily Chrysauginae (Insecta: Lepidoptera: Pyralidae). Although Pyralidae have been a focus of several molecular phylogenetic studies, including a few Chrysauginae genera, so far none of the three sloth moth
This paper contributes to ongoing debates on inclusive place branding by introducing a feminist ethics of care approach. While existing research often treats inclusion as a strategic or instrumental move, aimed at enhancing collaboration or democratic legitimacy, it is rarely framed as an ethical imperative. Moreover, prevailing human-centred perspectives tend to marginalize non-human and environm
Research aimThis paper examines place brand communication in marginalised urban areascharacterised by low levels of attractiveness to residents, visitors and investment. Most previous research on marginalised places has focused on issues such as crime prevention and securitydevelopment, rather than on branding and attractiveness. The aim of this research is to explore the roleof place branding eff
Corpus linguistic studies have shown that lexicon varies according to linguistic register, and cognitive studies have demonstrated that lexical aspects play a significant role in determining the veracity of people’s accounts. Both lines of research underpin the present study, where the aim is to explore how overall lexical properties (lexical density and lexical diversity, and noun, verb, and adje
This study explores how listeners use verb constructions to describe everyday sounds. It considers (i) how the verb constructions provide Gestalt to events in the form of activities, processes and states, and (ii) how the constructions correspond to different aspects of a soundscape (sound sources, acoustic properties, and listener reactions). We found that verb constructions primarily describe so
Heart failure is a global health concern whose burden is increasing as our population ages. Early diagnosis and accurate prognosis are critical for improving outcomes, highlighting the need for novel methods that can better identify and elucidate the pathophysiology of heart failure. The cardinal symptom of heart failure is exercise intolerance, yet most cardiac imaging is performed at rest, poten
The Council of Europe has very recently adopted the Framework Convention on Artificial Intelligence and Human Rights, Democracy and the Rule of Law. This article provides an initial analysis of the CoE AI Convention. It emphasizes the necessity of understanding the CoE AI Convention within the context of its adoption as an international treaty negotiated within the Council of Europe. This context
Based on more than thirty years' fieldwork, this book aims to increase the understanding of music played on elaborate wooden floats which form vital components in Japanese festivals with a religious dimension. The focus is on float-festivals in Aichi prefecture in central Japan; but wider perspectives, international as well as national, also come into play.Float-festivals date back several centuriThis book aims to increase the understanding of festival music in Japan. It is based on more than thirty years of fieldwork. Close study of one local festival in the town of Taketoyo is combined with a wider comparative analysis that covers most of the of the Aichi prefecture in central Japan. All these festivals are float-festivals. Charged with spiritual power, the floats serve as mobile shrines
The conductivity and stability of anion exchange membranes (AEMs) may be significantly enhanced by attaching the cations to the polymer backbones via flexible side chains. Here, we have tethered polydimethylfluorene with the bicyclic “cage-like” N-methylquinuclidinium (PdF-Qui) and the monocyclic N,N-dimethylpiperidinium (PdF-Pip) cations, respectively, via flexible side chains and studied key AEM
PurposeAdvanced wastewater treatment (AWT) methods, such as the use of ozone (O3) and granular activated carbon (GAC), have been shown to mitigate toxic impacts on receiving waters. However, life cycle assessments (LCAs) on AWT technologies commonly evaluate toxicity through chemical analysis and conclude that the increased toxicity caused by operational inputs exceeds the reduction in toxicity vi
This thesis develops an application-oriented framework to identify and predict residential demand-side flexibility from the temporal structure of electricity use, rather than energy totals. We construct structure-based, price-aligned labels that track shifts between peak and off-peak hours, and train three complementary models: a next-day behavioral classifier (M1) for short-horizon operations, a
