Objective: To evaluate aggrecanase activity after traumatic knee injury in a rat model by measuring the level of aggrecanase-generated Ala-Arg-Gly-aggrecan (ARG-aggrecan) fragments in synovial fluid, and compare with ARG-aggrecan release into joint fluid following human knee injury. To evaluate the effect of small molecule inhibitors on induced aggrecanase activity in the rat model. Method: An enz

The use of household electricity and domestic hot water has been measured for 72 apartments in an apartment building located in the south of Sweden. The measurements were carried out with samples every 6 s, a tenfold increase in resolution compared to available published data, during a measurement period of five days, in the winter season, including a weekend. The influence of the time resolution

BACKGROUND: Brain injury is considered the main cause of death in patients who are hospitalized after cardiac arrest (CA). Induced hypothermia is recommended as neuroprotective treatment after (CA) but may affect prognostic parameters. We evaluated the effect of delayed neurological prognostication on the mode of death in hypothermia-treated CA-survivors. STUDY DESIGN: Retrospective study at a Swe

Abstract in Uncoded languages U ranijim viktimološkim istraživanjima naglašene su jednostrane slike kategorije „žrtva“ i „zločinac“. Istraživači su isticali važnost priča i usmjerili fokus analize na priče o viktimizaciji, ali istraživači nisu analizirali poslijeratne intervjue kao arenu gdje se odigrava borba za status žrtve. Ovim člankom pokušava se popuniti ta praznina analiziranjem priča 27 osPrevious research on victimhood often has presented a one-sided picture of the “victim” and “perpetrator”. Researchers have emphasized the importance of narratives and they have focused on narratives about victimhood, but a researcher has not analyzed post-war interviews as a competition for victimhood. This article tries to fill this gap using stories told by survivors of the Bosnian war during t

We study analytically the tracer particle mobility in single-file systems with distributed friction constants. Our system serves as a prototype for nonequilibrium, heterogeneous, strongly interacting Brownian systems. The long time dynamics for such a single-file setup belongs to the same universality class as the Rouse model with dissimilar beads. The friction constants are drawn from a density r

Purpose: To explore how the rehabilitation plan influences the rehabilitation process and its outcome in people with late effects of polio participating in an individualised goal-oriented interdisciplinary rehabilitation programme. Methods: Four women and two men with late effects of polio were interviewed before rehabilitation, at discharge, and at follow-up. Data were analysed according to the c

We investigated test to retest reliability and intraindividual variability of Romberg ratios in quiet stance posturography. Thirty-six healthy young adults (17 males, 19 females aged 15-38 years) were divided into 3 groups with different time-intervals between consecutive trials (20min, 3h and 24h respectively). Each group performed 5 posturography recordings in a randomized order of eyes open (EO

We describe the possibility to create solid-like protein samples whose structural and mechanical properties can be varied and tailored over an extremely large range in a very controlled way through an arrested spinodal decomposition process. We use aqueous lysozyme solutions as a model globular protein system. A combination of video microscopy, small-angle neutron and X-ray scattering and reverse

Breast-cancer-derived cell lines are an important sample source for cancer proteomics and can be classified on the basis of transcriptomic analysis into subgroups corresponding to the molecular subtypes observed in mammary tumors. This study describes a tridimensional fractionation method that allows high sequence coverage and proteome-wide estimation of protein expression levels. This workflow ha

The genus Klyngon Hansson is revised and expanded to include 13 species, 11 of which are newly described: K. albicornis, K. aulacis, K. brasilense, K. copaiferae, K. costalimai, K. gibberum, K. guimaraesi, K. hortense, K. pegosoma, K. petalon, K. serjaniae. The inclusion of the new species necessitates a change of the morphological definition of the genus and diagnostic characters are modified or

Accurate characterization of the astrometric errors in the forthcoming Gaia catalogue is essential for making optimal use of the data. Using small-scale numerical simulations of the astrometric solution, we investigate the expected spatial correlation between the astrometric errors of stars as function of their angular separation. Extrapolating to the full-scale solution for the final Gala catalog

In exploratory high-dimensional data analysis, local intrinsic dimension estimation can sometimes be used in order to discriminate between data sets sampled from different low-dimensional structures. Global intrinsic dimension estimators can in many cases be adapted to local estimation, but this leads to problems with high negative bias or high variance. We introduce a method that exploits the cur

Double-differential dijet cross-sections measured in pp collisions at the LHC with a 7 TeV centre-of-mass energy are presented as functions of dijet mass and half the rapidity separation of the two highest-p(T) jets. These measurements are obtained using data corresponding to an integrated luminosity of 4.5 fb(-1), recorded by the ATLAS detector in 2011. The data are corrected for detector effects

Three sets of research criteria are available for diagnosis of Alzheimer's disease in subjects with mild cognitive impairment: the International Working Group-1, International Working Group-2, and National Institute of Aging-Alzheimer Association criteria. We compared the prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage according to these criteria. Subjects wi

Aquatic habitats are usually structured by light attenuation with depth resulting in different microalgal communities, each one adapted to a certain light regime by their specific pigment composition. Several taxa contain pigments restricted to one phylogenetic group, making them useful as marker pigments in phytoplankton community studies. The nuisance and invasive freshwater microalga Gonyostomu

Abstract in UndeterminedAccording to cognitive models, negative post-event processing rumination is a key maintaining factor in social anxiety disorder (SAD). Analogue research has supported the differentiation of self-focus into different modes of self-focused attention with distinct effects on rumination in depression and social anxiety. The purpose of this study was to replicate these effects w

This study evaluated a technique to allow the long-term monitoring of individual fishes of known sex in the wild using sex confirmation in close proximity to the reproductive period combined with individual tagging. Hundreds of partially migratory roach Rutilus rutilus were tagged with passive integrated transponders (PIT) following sex determination in spring and various performance measures were

The causes for malignant progression of disseminated tumors and the reasons recurrence rates differ in women with different breast cancer subtypes are unknown. Here, we report novel mechanisms of tumor plasticity that are mandated by microenvironmental factors and show that recurrence rates are not strictly due to cell-intrinsic properties. Specifically, outgrowth of the same population of incipie