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Aim: The purpose of this study was to investigate the relationship between maximum oxygen uptake (VO2PEAK) and body fat in young children on a population-based level. Methods: Participants were 586 children (311 boys and 275 girls) aged 6.8 +/- 0.4 years, recruited from a population-based cohort. VO2PEAK was measured by indirect calorimetry during a maximal exercise test. Percent body fat (BF%) wa
Background: Activating KRAS and BRAF mutations predict unresponsiveness to EGFR-targeting therapies in colorectal cancer (CRC), but their prognostic value needs further validation. In this study, we investigated the impact of KRAS codons 12 and 13, and BRAF mutations on survival from CRC, overall and stratified by sex, in a large prospective cohort study. Methods: KRAS codons 12 and 13, and BRAF m
Written submissions or comments as a response on an EIS (Environmental Impact Statement) rank as one of the most common forms of public participation. Within public participation research there appears to be an international dearth of knowledge concerning such written submissions. The possible impact of such responses on an EIS is - with few exceptions - seldom put in focus. The aim in the present
Soot particles can be formed in hydrocarbon flames as a result of an inefficient combustion process. The particles are near-spherical, and at later stages in the soot growth process, they form chainlike sparse aggregates. When applying optical diagnostic methods, this aggregation influences the evaluation of soot properties based on assumptions of isolated particles. In this paper an efficient and
Prevention and control of infectious diseases is seriously hampered by an increasing prevalence of bacteria that are resistant towards conventional antibiotics. Resistant bacteria are often the root cause of infections that trigger the complex clinical syndrome called sepsis, which is a concern for high morbidity and mortality. Despite extensive basic research and clinical studies, treatment of se
Objectives To describe clinical history and ultrasound findings in patients with tubal carcinoma. Methods Patients with a histological diagnosis of tubal cancer who had undergone preoperative ultrasound examination were identified from the databases of 13 ultrasound centers. The tumors were described by the principal investigator at each contributing center on the basis of ultrasound images, ultra
Previous research has found that weak institutions can hamper investment and alter patterns of trade. However, little is known about the impact of institutional quality on offshoring. This lack of knowledge is surprising, given that offshoring has become an important part of many firms' internationalization strategies. This study uses detailed firm-level data for the 1997-2005 period to examine th
Biobank samples stored in biobanks give researchers and respiratory healthcare institutions access to datasets of analytes valuable for both diagnostic and research practices. The usefulness of these samples in clinical decision-making is highly dependent on their quality and integrity. New procedures that better preserve sample integrity and reduce degradation are being developed to meet the need
We determine relative photoemission time delays between valence electrons in different noble gas atoms (Ar, Ne and He) in an energy range between 31 and 37 eV. The atoms are ionized by an attosecond pulse train synchronized with an infrared laser field and the delays are measured using an interferometric technique. We compare our results with calculations using the random phase approximation with
A unified description of solvation in dielectric media characterized by a static relative permittivity e is presented. The approach is based on probability distributions representing fluctuating dipole moments and electric fields and goes beyond the traditional mean-field approach. In addition to reproducing some standard results, we present an expression for the solvation free energy of a dielect
The surface and near-surface chemical composition of BiFe0.5Mn0.5O3 has been studied using a combination of low photon energy synchrotron photoemission spectroscopy, and a newly developed maximum entropy finite element model from which it is possible to extract the depth dependent chemical composition. In the uppermost few unit cells, an overabundance of Bi, and a deficiency of Fe and Mn are obser
Mutations in pancreatic duodenal homeobox 1 (PDX-1) can cause a monogenic form of diabetes (maturity onset diabetes of the young 4) in humans, and silencing Pdx-1 in pancreatic β-cells of mice causes diabetes. However, it is not established whether epigenetic alterations of PDX-1 influence type 2 diabetes (T2D) in humans. Here we analyzed mRNA expression and DNA methylation of PDX-1 in human pancr
We assessed the relative merits of two approaches for including polarization effects in classical force fields for the sulfate anion. One of the approaches is the explicit shell model for atomic polarization and the other is an implicit dielectric continuum representation of the electronic polarization, wherein the polarizability density is spatially uniform. Both the solvation and ion association
The major assumption made is that language as a natural system is both self-organising and self-referential. Compared to common syntactic-semantic approaches, the present approach is ecological and builds on the unambiguous identification of textual agents and agencies together with their objectives. Because information transaction cannot be studied without an emphasis on the text producer’s text
Popular Abstract in Swedish Enbart i Sverige drabbas tusentals personer årligen, kvinnor som män, av plötsligt cirkulationsbortfall (akut ischemi) i ett ben till följd av blodpropp i en artär. Tillståndet är akut och innebär ett direkt hot mot såväl liv som lem. Personer som drabbas är ofta äldre, och de har ofta många andra sjukdomar med sig i bagaget. För att rädda benet, och patienten, krävs aBackground: Acute ischemia of the lower limb is a vascular emergency associated with amputation and death. Patients suffering from acute limb ischemia are usually elderly, and multiple comorbidities are often present. Intra-arterial thrombolysis is, perhaps, the most important minimal-invasive treatment option available today. Although uncontrolled hemorrhage is a dreaded complication, it is consi
The development and assessment of spectrum management methods for the copper access network are usually conducted under the assumption of accurate channel information. Acquiring such information implies, in practice, estimation of the crosstalk coupling functions between the twisted-pair lines in the access network. This type of estimation is not supported or required by current digital subscriber
Results are presented of a search for supersymmetric particles in events with large missing transverse momentum and at least one heavy flavour jet candidate in root s = 7 TeV proton proton collisions. In a data sample corresponding to an integrated luminosity of 35 pb(-1) recorded by the ATLAS experiment at the Large Hadron Collider, no significant excess is observed with respect to the prediction
Jet cross sections have been measured for the first time in proton-proton collisions at a centre-of-mass energy of 7 TeV using the ATLAS detector. The measurement uses an integrated luminosity of 17 nb(-1) recorded at the Large Hadron Collider. The anti-k(t) algorithm is used to identify jets, with two jet resolution parameters, R = 0.4 and 0.6. The dominant uncertainty comes from the jet energy s
