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DNA sequence variation can have different effects on the amino acid sequence of a protein, depending on what type of alteration is made and the position of it. While missense and nonsense variants can substitute one amino acid for another or lead to a premature stop codon respectively, synonymous variation does not directly alter the amino acid sequence of a protein. Though synonymous variants see
Flygindustrin närmar sig ett vägval där sektorn kommer behöva bestämma sig för vilken typ av framtida energimöjligheter den ska använda sig av. En väg är att även fortsättningsvis använda sig konventionellt flygbränsle vilket med stor sannolikhet kommer leda till fortsatt ökande utsläpp globalt, och den andra vägen leder sektorn till hållbart flygbränsle, vätgasdrift och batteridrivna elektriska fThe aviation sector is approaching a crossroad where the industry will have to decide on what path to take going forward in terms of its’ energy needs. One path continues with the usage of non-renewable fuel resources such as jet fuel with the clear potential that global emissions will continue to rise, whereas the other path leads to newer technologies such as sustainable aviation fuels, hydrogen
Serious violence that is connected to gangs has escalated drastically in Sweden in the past years. I argue that understanding the values and attractions of joining a criminal gang are crucial in order to prevent further recruitment. In order to successfully reintegrate previous gang members, increased knowledge of the exit-process is needed. Hence, this thesis is based on interviews with eight def
Vilken roll har kommuner i arbetet med att minska konsumtionsbaserade utsläpp? Beroende på vilket utsläppsperspektiv som tillämpas kan ett lands eller kommuns utsläpp av växthusgaser antingen minska eller öka. Det traditionella produktionsbaserade perspektivet räknar direkta utsläpp som sker inom det geografiska området. Det alternativa konsumtionsbaserade perspektivet inkluderar utsläpp som skerLocal governments (LG) have been given a key role in the work of reducing greenhouse gas (GHG) emissions. To find the local drivers of GHG emission LG can develop an inventory that accounts for all the emissions associated with the municipality. A fundamental difference concerns whether the inventory accounts for the emissions that occur within the geographical boundaries or if emissions from good
Special purpose acquisition companies (SPACs) are shell companies with no operational assets with the sole purpose of using the raised capital from the initial public offering (IPO) to acquire a private target firm within a predetermined time frame. This financial vehicle has in recent years surged in interest and media coverage. Nevertheless, the long-term performance of the SPACs post-merger is
Motion detection is an essential technology and it has numerous use-cases, such as security tracking, automated door opening systems, and IP cameras. Commonly, passive infrared sensors or radio frequency sensors are used for motion detection. However, this thesis focuses on performing motion detection using existing hardware at audio frequencies. Specifically, it aims to implement a motion detecti
Syfte: Syftet med arbetet är att jämföra byggmetoderna stolpverk och regelverk ur aspekterna tid, kostnad, materialåtgång, byggnadsmetoder, kompetens och design. Frågorna man ställde var: Frågeställning: Hur skiljer sig ett hus byggt med stolpverks metoden kontra ett likvärdigt hus byggt med regelverks metoden? Vilka för- och nackdelar finns det med stolpverkshus jämfört med regelverkshus? MeAim: The purpose of the work is to compare construction methods of timber framing and stud framing from the aspects of time, cost, material consumption, construction methods, competence and design. The questions asked were: Research questions: How does a house built with the timber frame method differ from an equivalent house built with the stud framing method? What are the advantages and disad
Introduction: Superfruits have been promoted as nutrient-rich food that can improve your health, however, many scientists argue that the validation of the term is based on exaggeration of the limited studies that are available. Background: The chemical composition of a food is complex and there are many substances that can affect the human body. One such group of substances are fatty acids (FAs),
Urban areas are responsible for a significant part of greenhouse gas emissions. Megacities, especially, have cumulative impacts due to different anthropogenic heat sources and urban heat island phenomena. It is therefore vital to replace fossil fuel burning heating sources with renewable sources in the current building stock. Renewable energy sources can be applied through building energy retrofit
The reason behind brain pericyte death in Alzheimer's disease Alzheimer's disease (AD) is a widespread neurodegenerative disorder with more than 46 million people living with AD worldwide. The most characteristic clinical symptoms of AD are memory loss and behavioural issues, affecting the daily life of those suffering from AD and their caregivers. Unfortunately, despite extensive researc
Mantle cell lymphoma (MCL) with Myc aberrations has previously been shown to be associated with poor survival and worse response to current treatment strategies. This study aims to investigate the association between Myc overexpression and clinical outcome and to identify drugs targeting MCL with Myc alterations. Data from the two patient cohorts BLISS and N-MCL2/3 was analyzed, and the associatio
Plantera skog i hagen eller på vetefältet? Att börja använda marken i stor skala i form av jordbruk, städer och nedhuggning av skog var en förutsättning till att den mänskliga civilisationen skulle uppstå, men det har inte kommit utan konsekvenser för planeten. Att använda marken på ett hållbart sätt är avgörande för att bemöta de stora miljöproblemen i världen som klimatförändringar och förlustenThe environmental effects, not least on biodiversity, of land use and land use change provide major challenges when sustainability goals are to be met along with demand for production and other ecosystem services. Here I systematically review literature on one major land use change, from agriculture to forest, and the implications for biodiversity. The aim is to provide information for land use de
Online dating is growing rapidly within society. In the light of the covid-19 pandemic, the popular online dating app Tinder provides a new social setting for dating and romantic relationships. There is some debate whether online dating apps liquify (devolves) love - as proposed by Zygmunt Bauman - or make dating more accessible and efficient. This thesis aims to understand and create knowledge of
Title: “With Great Freedom Comes Great Responsibility” - A Qualitative Study of Managers’ and Their Respective Employees’ Experiences of Mandatory Remote Work and Relationships in this Work Setting Authors: Anna Rebeka Dinnyes & Siri McGarvey Supervisor: Monika Müller, Lund University, Sweden Examiner: Stefan Sveningsson, Lund University, Sweden Course: BUSN49, Degree Project in Master’s P
This thesis investigates the quantization of field theories using the functional integral formalism. Gauge invariance necessitates a gauge-fixing procedure that chooses a unique field configuration from each gauge orbit. Faddeev and Popov suggested an adjustment to the action that implements gauge fixing in this framework, however it has been found that this procedure fails to uniquely fix the gau
Vi har testat en av teorierna för kvanttermodynamik med Hubbard-Holstein modellen på en dimer. Resultaten visar att effekten av fjädern är att utjämna de typiska kännetecknen i arbetet utfört av systemet. Vi har sett att systemet kan agera som ett batteri som kan laddas. Vi såg också att det var viktigt vilken ordning vi ändrade parametrarna i systemet, som vi förväntade oss av klassisk termodynamThe goal of this project is to characterize the quantum thermodynamics of a Hubbard-Holstein dimer. We explore how the standard formalism of quantum thermodynamics behaves in the context many-body physics. To this end, the simplest possible lattice model which includes electron and electron-phonon interactions is used, namely the Hubbard-Holstein dimer. The system is time evolved using exact diago
Syfte: Undersöka om det går att utläsa någon variation i företags goodwillnedskrivning år 2019 och 2020 då åren har präglats av både en låg- och högkonjunktur. Metod: Studien har genomförts med en utvärderingsmetodik och kvantitativ metod. Datainsamlingen består utav företags årsredovisningar där utvalda poster har använts för analyskapitlet. Teoretiska perspektiv: Referensramen består av tidigaPurpose: Examine whether there is a difference in companies’ impairment of goodwill in the years 2019 and 2020 as the years have been characterized by both a recession and an economic boom. Methodology: This study has implemented an evaluative approach with the aid of quantitative method. The data was collected from annual reports where selected entries have been used in the analysis chapter. Th
Swedish youth-centres are characterized by their vision of being a “meeting place for all”. To fulfil this vision, inclusion has become a relevant concept and tool for those working within these centres. This thesis is based on interviews with seven youth-workers and managers within youth-centres in a large Swedish municipality. The aim of the study is to investigate how youth-workers and managers
Antal fordon i trafiken börjar bli allt fler och fler. Detta leder till att vägar behöver underhållas emellanåt. För att åtgärda vägarna så krävs det vägarbetare på plats, 90% av dessa vägarbetare känner oro dagligen på sitt jobb. Anledningen till deras oro är att många trafikanter inte tar någon hänsyn till vägarbetare, de kör aggressivt, hänsynslöst och över hastighetsgränsen. Under åren 2003-20The number of vehicles in traffic is increasing. This means that roads need to be maintained regularly. To repair the roads, road workers are required on site. Ninety percent of these road workers feel anxious daily at their work. The reason for their concern is that many road users do not pay any attention to road workers, they drive aggressively, ruthlessly and over the speed limit. During the y
Over the last decades, the Swedish insurance industry has seen decreased entry barriers due to deregulation and emerging new technologies, which have the potential to disturb the stagnated and consolidated competitive landscape of the industry. Initiated by newcomers like American insurance startup Lemonade, and later Swedish Hedvig among others, there is an increased push toward digitalization, t
