Human genetic studies support an inverse causal relationship between leukocyte telomere length (LTL) and coronary artery disease (CAD), but directionally mixed effects for LTL and diverse malignancies. Clonal hematopoiesis of indeterminate potential (CHIP), characterized by expansion of hematopoietic cells bearing leukemogenic mutations, predisposes both hematologic malignancy and CAD. TERT (which

Introduction: During the COVID-19 pandemic various degrees of lockdown were applied by countries around the world. It is considered that such measures have an adverse effect on mental health but the relationship of measure intensity with the mental health effect has not been thoroughly studied. Here we report data from the larger COMET-G study pertaining to this question. Material and Methods: Dur

Encounters between patients in homecare and nursing students are cultural events where students, in principle, are in unknown territory. This study illuminated how nursing students recount (inter)actions in social relations in Danish homecare settings, illustrated by students with a self-appointed immigrant background. The study consisted of semi-structured interviews with eight nursing students.

Premise: Floral scent is a complex trait that mediates many plant–insect interactions, but our understanding of how floral scent variation evolves, either independently or in concert with other traits, remains limited. Assessing variation in floral scent at multiple levels of biological organization and comparing patterns of variation in scent to variation in other floral traits can contribute to

Objective: The role of HIV exposure in determining growth among HIV-uninfected children is debated. We determined whether intrauterine HIV exposure influences linear growth in a cohort of Ethiopian children followed up to 18 months of age in public health facilities in Adama city, Ethiopia. Methods: Participants were offspring of pregnant women enrolled in a prospective cohort study that included

A search is presented for the production of a single top quark via left-handed flavour-changing neutral-current (FCNC) interactions of a top quark, a gluon and an up or charm quark. Two production processes are considered: u+ g→ t and c+ g→ t. The analysis is based on proton–proton collision data taken at a centre-of-mass energy of 13 TeV with the ATLAS detector at the LHC. The data set correspond

We consider a numerical approximation of a linear quadratic control problem constrained by the stochastic heat equation with nonhomogeneous Neumann boundary conditions. This involves a combination of distributed and boundary control, as well as both distributed and boundary noise. We apply the finite element method for the spatial discretization and the linear implicit Euler method for the tempora

The historical subclassification of diabetes into predominantly types 1 and 2 is well appreciated to inadequately capture the heterogeneity seen in patient presentations, disease course, response to therapy and disease complications. This review summarises proposed data-driven approaches to further refine diabetes subtypes using clinical phenotypes and/or genetic information. We highlight the bene

A new combination, Nephromopsis annae (Oxner) A.Thell & Divakar is proposed and the basionym Cetrariasubalpina Imshaug is preferred over the combination in Nephromopsis.

Fine quality coating materials for a variety of surfaces using environmentally friendly substrates are continuously in demand. A large proportion of acrylate derivatives, which are toxic and hazardous, were found in most of the coating formulations. Many efforts have been done to replace acrylate derivatives with other materials derived from renewable resources. In this work, several formulations

We present the first measurement of event-by-event fluctuations in the kaon sector in Pb – Pb collisions at sNN=2.76 TeV with the ALICE detector at the LHC. The robust fluctuation correlator νdyn is used to evaluate the magnitude of fluctuations of the relative yields of neutral and charged kaons, as well as the relative yields of charged kaons, as a function of collision centrality and selected k

Ongoing and future climate change will affect our built environment. It will have an impact on how we should design our structures to withstand the future environment. One important load when designing buildings in high latitudes and high elevations is the snow load, which in many countries is the governing load for roofs and other structural parts. A warmer climate may lead to a reduction in snow

The interaction of octanoic acid and its conjugate base sodium octanoate with α-cyclodextrin was studied by 1H NMR and isothermal titration calorimetry, respectively, at 298.15 K. The results are in agreement with a 1:1 stoichiometry in the complex. The binding of octanoate with α-cyclodextrin is characterized by a positive entropy, stressing the relevance of hydrophobic interactions. Based on the

This article presents the results of two studies of Higgs boson properties using the WW∗(→ eνμν) jj final state, based on a dataset corresponding to 36.1 fb - 1 of s=13 TeV proton–proton collisions recorded by the ATLAS experiment at the Large Hadron Collider. The first study targets Higgs boson production via gluon–gluon fusion and constrains the CP properties of the effective Higgs–gluon interac

Discrepancies in views of the Self are suggested to be negatively related to well-being (Higgins, 1987). In the present study, we used a novel concept, Personality Estimation Discrepancy (PED), to test this classic idea. PED is defined as the computed difference between how one view oneself (Self-Perceived Personality) and a standard Big Five test (IPIP-NEO-30). In a pre-registered (osf.io) UK onl

Material quality, and opportunities for multiple reprocessing, need to be considered when analysing the overall carbon footprint and energy efficiency of plastic products in life cycle assessments. This is rarely done today. This paper presents a case study evaluating a closed-loop recycling system involving a plastics manufacturer in Sweden which produces and reprocesses multiple-use plastic dini