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I väntan på Meryl Streep eller Typecasting i kommunal regi

Ekonomens roll är otydlig eftersom det är stor spridning i ekonomers uppgifter, förväntningar och handlingsutrymme. Otydligheten medför att transaktionskostnaderna i organisationen blir stora. Ett sätt att tydliggöra rollerna är att utgå från hur ekonomer interagerar med organisationen. Fyra rolltyper framträder.

Pressurized fluid extraction of bioactive compounds from Phormidium species

In the search for new functional ingredients with potential use in the food industry, extracts of unknown species of microalgae, such as Phormidium species have been studied. Three solvents of different polarities (i.e., hexane, ethanol, and water) have been used to obtain pressurized liquid extracts with different compositions. Moreover, extractions were performed at four different extraction tem

Stroke alters behavior of human skin-derived neural progenitors after transplantation adjacent to neurogenic area in rat brain

Background: Intracerebral transplantation of human induced pluripotent stem cells (iPSCs) can ameliorate behavioral deficits in animal models of stroke. How the ischemic lesion affects the survival of the transplanted cells, their proliferation, migration, differentiation, and function is only partly understood. Methods: Here we have assessed the influence of the stroke-induced injury on grafts of

A time projection chamber with GEM-based readout

For the International Large Detector concept at the planned International Linear Collider, the use of time projection chambers (TPC) with micro-pattern gas detector readout as the main tracking detector is investigated. In this paper, results from a prototype TPC, placed in a 1. T solenoidal field and read out with three independent Gas Electron Multiplier (GEM) based readout modules, are reported

Once upon a time in Västmanland-the power of narratives or how the "truth" unfolds

In 2014 a small fire started in a forest in central Sweden. Within a few days it developed into the largest wildfire in Sweden in the last 50 years. As the scale of the fire increased, so did the need for direction and coordination of the resources engaged in the response operation. Both official investigators and the research community have studied the challenges and come up with recommendations

Non-gastric H+/K+ ATPase is present in the microvillous membrane of the human placental syncytiotrophoblast

In humans, the non-gastric H+/K+ ATPase (ATP1AL1) has previously been shown to be expressed in the epithelia of skin, kidney and colon. In this study we tested the hypothesis that the non-gastric H+/K+ ATPase is localized to the syncytiotrophoblast, the transporting epithelium of the human placenta. Microvillous (MVM) and basal plasma membranes (BM) of the syncytiotrophoblast were isolated from te

Activity and protein expression of the Na+/H+ exchanger is reduced in syncytiotrophoblast microvillous plasma membranes isolated from preterm intrauterine growth restriction pregnancies

Regulation of syncytiotrophoblast intracellular pH is critical to optimum enzymatic and transport functions of the placenta. Previous studies of Na+/H+ exchanger (NHE) activity in the placenta from pregnancies complicated by intrauterine growth restriction (IUGR) have produced conflicting results. The possible role of altered placental pH regulation in the development of acidosis in some fetuses s

Influence of Fibers and Particle Size Distribution on Food Rheology

This chapter deals with the rheology of dietary fiber (DF) suspensions and how the microstructural properties influence it. The origin of the vegetable DF investigated was tomato, apple, carrot, potato, parsnip, and yacon.The amount and composition of the soluble/insoluble fiber have been measured for each type of fiber. For the insoluble part the microstructural properties such as form, degree of

Adaptation response surfaces for managing wheat under perturbed climate and CO2 in a Mediterranean environment

Adaptation of crops to climate change has to be addressed locally due to the variability of soil, climate and the specific socio-economic settings influencing farm management decisions. Adaptation of rainfed cropping systems in the Mediterranean is especially challenging due to the projected decline in precipitation in the coming decades, which will increase the risk of droughts. Methods that can

Intra- and interregional coregulation of opioid genes : broken symmetry in spinal circuits

Regulation of the formation and rewiring of neural circuits by neuropeptides may require coordinated production of these signaling molecules and their receptors that may be established at the transcriptional level. Here, we address this hypothesis by comparing absolute expression levels of opioid peptides with their receptors, the largest neuropeptide family, and by characterizing coexpression (tr

The effect of stator design on flowrate and velocity fields in a rotor-stator mixer—An experimental investigation

Rotor-stator mixers (RSMs) are available in different designs, e.g. with different number of stator slots and slot dimensions. However, the relationship between stator design and the RSM hydrodynamics is not well understood. Consequently, manufacturers still base design and stator screen recommendations on trial-and-error. This study reports experimental measurements of how the flowrate through th

Students for global oncology: Building a movement for student education and engagement in an emerging field

Program/Project Purpose: Increased recognition of the global cancer burden and inequalities in care and outcomes have led to the growing field of global oncology, focused on strengthening health systems to improve cancer prevention and care. Motivated students and trainees are in need of pathways to approach these challenges. In 2012, Harvard Medical students formed Students for Global Oncology (S

On allosteric modulation of P-type Cu(+)-ATPases

P-type ATPases perform active transport of various compounds across biological membranes and are crucial for ion homeostasis and the asymmetric composition of lipid bilayers. Although their functional cycle share principles of phosphoenzyme intermediates, P-type ATPases also show subclass-specific sequence motifs and structural elements that are linked to transport specificity and mechanistic modu

Defining HIV-1 transmission clusters based on sequence data : a systematic review and perspectives

Understanding HIV-1 transmission dynamics is relevant to both screening and intervention strategies of HIV-1 infection. Commonly, HIV-1 transmission chains are determined based on sequence similarity assessed either directly from a sequence alignment or by inferring a phylogenetic tree. This review is aimed at both nonexperts interested in understanding and interpreting studies of HIV-1 transmissi

Electronic structure of strongly correlated materials : From one-particle to many-body theory

One of the great challenges of modern condensed matter theory is to develop reliable and practical methods for describing the electronic structure of strongly correlated materials fully from first principles. It has been known for a long time that the widely used Kohn-Sham density functional theory within the local density approximation (LDA) often fails for these systems. This paper describes the

Constructive Alignment as a Means to Establish Information Literacy in the Curriculum

Constructive alignment is the pedagogical principal which connects learning goals and learning activities with assessment. Learning goals should inform the student about what they’ll know once they finish the course. Learning activities is what the student needs to do to fulfill the goals. The assessment measures to what degree the student reaches the learning goals. The principal of constructive

The effects of TTS-scopolamine, dimenhydrinate, lidocaine, and tocainide on motion sickness, vertigo, and nystagmus

The effects of TTS-scopolamine, dimenhydrinate, lidocaine, and tocainide on motion sickness and vertigo and on caloric and postrotatory nystagmus were evaluated in healthy volunteers. TTS-scopolamine was administered transdermally (delivering approximately 10 micrograms X h-1 scopolamine base) and 100 mg dimenhydrinate orally. Lidocaine and tocainide were administered intravenously (average plasma