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Ny tid för uroxen

Vad innebär domesticeringen egentligen för en djurart – och vad krävs för att den återigen skulle kunna ses som ”ursprunglig” eller vild? Kan den utdöda uroxen återskapas?

Adaptive heterosubtypic immunity to low pathogenic avian influenza viruses in experimentally infected mallards

Mallards are widely recognized as reservoirs for Influenza A viruses (IAV); however, host factors that might prompt seasonality and trends in subtype diversity of IAV such as adaptive heterosubtypic immunity (HSI) are not well understood. To investigate this, we inoculated mallards with a prevailing H3N8 low pathogenic avian influenza virus (LPAIV) subtype in waterfowl to determine if prior infect

Symptom trajectory and symptom burden in older people with multimorbidity, secondary outcome from the RCT AGe-FIT study

AIM: The aim of this study was to follow the symptom trajectory of community-dwelling older people with multimorbidity and to explore the effect on symptom burden from an ambulatory geriatric care unit, based on comprehensive geriatric assessment.BACKGROUND: Older community-dwelling people with multimorbidity suffer from a high symptom burden with a wide range of co-occurring symptoms often result

Note from the field : Applying a ‘human rights cognitive style’ in the Raoul Wallenberg Institute’s work on human rights education with universities

This note draws on both the Raoul Wallenberg Institute’s (RWI) international cooperation programmes with universities to advance human rights education and the concepts of a ‘human rights cognitive style’ and ‘local cognitive style’ as developed by Benjamin Gregg in his recent theory of The Human Rights State (2016). We analyse how to facilitate positive attitudinal change towards human rights acr

G protein-coupled Estrogen Receptor 1 (GPER1)/GPR30 Increases ERK1/2 Activity Through PDZ-dependent and -independent Mechanisms

G protein-coupled receptor 30 (GPR30), also called G protein-coupled estrogen receptor 1 (GPER1), is thought to play important roles in breast cancer and cardiometabolic regulation, but many questions remain about ligand activation, effector coupling, and subcellular localization. We showed recently that GPR30 interacts through the C-terminal type I PDZ motif with SAP97 and protein kinase A (PKA)-

Long-Term Cognitive Decline in Dementia with Lewy Bodies in a Large Multicenter, International Cohort

Background/Objective: The aim of this study was to describe the rate and clinical predictors of cognitive decline in dementia with Lewy bodies (DLB), and compare the findings with Alzheimer's disease (AD) and Parkinson's disease dementia (PDD) patients. Methods: Longitudinal scores for the Mini-Mental State Examination (MMSE) in 1,290 patients (835 DLB, 198 PDD, and 257 AD) were available from 18

The Multi-Blade Boron-10-based neutron detector for high intensity neutron reflectometry at ESS

The Multi-Blade is a Boron-10-based gaseous detector introduced to face the challenge arising in neutron reflectometry at pulsed neutron sources. Neutron reflectometers are the most challenging instruments in terms of instantaneous counting rate and spatial resolution. This detector has been designed to cope with the requirements set for the reflectometers at the upcoming European Spallation Sourc

Auditory Feedback Regulation of Perturbed Stance in Stroke Patients

The effect of auditory input on impaired postural control perturbations was evaluated in two groups of stroke patients participating in a rehabilitation programme after a recent (< 12 months) and single episode of stroke, or less recent (> 12 months), and multiple episodes of stroke. Auditory input took the form of feedback signals generated by the forces actuated by the feet on a force platform i

Clinical aspects of eye tracking test

The eye tracking test is today a well established part of clinical otoneurological examination. In the present paper some applications of the test in evaluating of the level of lesion within the vestibular system are reviewed.

Visually evoked slow eye movements, visual-vestibular interaction, and infratentorial lesions

The maximum velocity gain of smooth pursuit and optokinetic, vestibular, and optovestibular slow phases was examined in 15 patients with pontine, 10 with medullary, 10 with cerebellar, and 5 with combined cerebello-brain stem disorders. Marked dissociations were observed between smooth pursuit and optokinetic slow phases, especially in medullary disease. A cerebellar deficit enhanced slow phase ve

On the metallicity dependence of the [Y/Mg]–age relation for solar-type stars

Several recent studies of solar twins in the solar neighbourhood have shown a tight correlation between various elemental abundances and age, in particular [Y/Mg]. If this relation is real and valid for other types of stars as well as elsewhere in the Galaxy, it would provide a very powerful tool to derive ages of stars without the need to resort to determining their masses (evolutionary stage) ve