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Små molekyler med stor inverkan - interferon alfas roll i Systemisk Lupus Erythematosus (SLE) Systemisk Lupus Erythematosus är en autoimmun sjukdom där immunförsvaret attackerar kroppens egna vävnader. Detta leder till en kronisk inflammation som kan yttra sig i en rad olika manifestationer beroende på var inflammationen sker. Sjukdomsaktiviteten går i perioder, dvs att den går upp i skov där patSystemic Lupus Erythematosus (SLE) is an autoimmune disease where the immune system is attacking the body and its tissues. This leads to a chronic inflammation that can affect different parts of the body and therefore present itself in a vast variety of symptoms. Depending on the activity of the disease it can go up in flares where the patients experience symptoms and then go down into recession.

Synchrotron and Free Electron Laser (FEL) light is becoming an increasingly sought after tool for almost all scientific research aspects. MAX IV Laboratory introduced the first 4th generation light source that provides the brightest synchrotron light in the world. Since all of the experiments at MAX IV rely only on Insertion Device (ID) radiation, the need for improving ID technology has subsequen

In this thesis work, experiments have been carried out to study the behavior of radio frequency power amplifier which is the one of the largest power consumers in a user equipment which is a mobile phone in this case. A CMW-500 which is a Rohde and Schwarz equipment has been used to emulate the base station. A user equipment has been chosen that operates in accordance with cat12 LTE. The input pat

Studiens syfte är att undersöka hur fiollärare jobbar för att motivera sina elever och vilka faktorer elever själva anser har betydelse för deras motivation vad gäller musicerande. Studien syftar också till att undersöka vilka egenskaper elever eftersöker hos en motiverande lärare. Utifrån tidigare forskning och litteratur kring motivationsarbete och övning, samt resultatet av intervjuer med fioll

Morfologiska likheter med asbest tillsammans med toxikologiska studier i celler och försöksdjur har väckt oro för de potentiella hälsoriskerna om nanotrådar kan bli luftburna och inandas vid hantering. Nanotrådar växta på substrat genom epitaxi kan riskera att skadas under hantering vid förberedelse för analys i mikroskop och detta examensarbete ämnar undersöka huruvida nanotrådar eller fragment a

Neural networks have an increasingly important role in the financial market, by offering a solution to stationarity and non-linearity whilst also providing robustness and predictive power. Options and option pricing are a fundamental area of interest in the daily activities of investment banks, hedge funds and trading firms in the financial market. Implied volatility is the focal point of these op

On April 25, 1983, STERN, a renowned German magazine, held a press conference attended by more than 200 journalists and 27 television crews from all around the world. On that day, STERN announced that it had obtained private diaries of Adolf Hitler through a confidential source and intended to publish them. The Hamburg based magazine had already signed several contracts with various European magaz

Jämställdheten mellan kvinnor och män i arbetslivet är en viktig del i arbetet mot ett mer jämställt samhälle. Denna uppsats syftar till att utreda hur Sverige har valt att tolka begreppet positiv särbehandling. Positiv särbehandling tillåter särbehandling, i de fall det är ett steg till att främja jämställdheten mellan kvinnor och män på arbetsplatsen. Begreppet är dock vagt formulerat. Detta innEquality between women and men in the workplace is important when working towards an equal society. This essay aims to investigate how Sweden has interpreted the exemption from discrimination called positive action. The concept is based on EU law and is formulated to promote equality between men and women at the workplace. This possibility for using positive action is, however, composed vaguely. T

December 2nd 2016 it was established that Oatly had a new co-owner, China Resources, a partnership that went against not only their own core values but also the values of their oat followers. However, it was not until 2019 the media storm drew in. Oatly owned the spotlight and the debates continued whether Oatly could be trusted or if boycott was the best decision. Oatly however, answered the crit

Multidimensional integrals are used in many areas of physics; electrodynamics, quantum mechanics and statistical physics, to name a few. Many integrals can not be solved analytically, but can instead be approximated numerically. VEGAS is a Monte Carlo integration algorithm, which specializes it in approximating multidimensional integrals. By treating each integration variable independently, VEGAS

Chile is one of the countries in South American working to achieve energy independence by introducing renewables energy to reduce its greenhouse gas emissions from conventional energy sources. Chile has a variety of water resources from the North to the South, where most of these resources are comprehended by short rivers that are exploited to produce hydro-electric power. Chile has a huge number

Syfte: Arbetets syfte var att undersöka hur medarbetare upplever deras chefers ledarskap och användning av olika grupper av påverkanstaktiker. Vidare var vi intresserade om detta påverkades eller modulerades något av chefernas egen ålder eller kön. Vidare ville vi även få en fördjupad förståelse hur denna relation mellan medarbetare, chef och påverkanstaktik påverkar medarbetarnas egenupplevda motPurpose: The purpose of this study was to generate an understanding of how followers experience their boss’s leadership as well as their use of different groups of influence tactics. Furthermore, we were interested in researching if this was affected or modulated by either the boss’s gender or age. We further wanted to generate a deeper understanding how the relation between follower and boss and

On November 17th, 2017, Electronic Arts, an American gaming company, publishes one of the most anticipated games of the year: Star Wars Battlefront 2. It is a first- and third-person shooter video game based on the Star Wars universe, with both single and multiplayer aspects. Upon its release, the game, in its beta stage, was heavily criticized. The criticism was regarding the status of the game’s

In this degree project, automatic live comments of the events in a football game are generated in text format. The events are detected using machine learning, where CNNs are fit using audio recordings and player positions of games. Suitable features are extracted, where several models are fit to detect different types of events. The results indicate that the detections of sound powers and referee

The combination of item non response and cluster analysis is a field which has not been explored to its full extent. This study aims to investigate which consequences a data set with missing values has on the algorithm of cluster analysis and which model for imputation should be suggested in order to minimize standard error and the optimal number of clusters. Basing our research on principal compo

Due to anthropogenically created climate change, global cities are facing inundation by rising sea levels. This study aimed to fill knowledge gaps in understanding the exposure of urban infrastructure such as roads, railways, buildings and parks to sea-level rise (SLR) scenarios, and how this would affect local populations. Three economic hubs, namely London (United Kingdom), Bangkok (Thailand) an

Phosphate is fundamental for optimal growth and reproduction for plants. However, due to low solubility, not all phosphorus in the soil is available to the plant. It has recently been discovered that plants can take up complex phosphate-containing organic compounds, such as phospholipids. This depends on membrane transporters, more specifically lipid flippases. In the model plant Arabidopsis, the