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Transient evolution of the heat transfer and the vapor film thickness at the drop impact in the regime of film boiling

When a drop impinges onto a wall heated above the Leidenfrost temperature, a very thin vapor film is formed at the interface between the liquid and the solid substrate. This vapor layer modifies the impact behavior of the drop and induces a significant decrease in heat transfer. A model is proposed for the growth of this vapor layer and its resistance to the heat transfer. The main assumptions are

Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration

Alzheimer's disease (AD) is pathologically characterized by the accumulation of amyloid-β (Aβ) plaques, neurofibrillary tangles and widespread neuronal loss in the brain. In recent years, blood biomarkers have emerged as a realistic prospect to highlight accumulating pathology for secondary prevention trials. Neurofilament light chain (NfL), a marker of axonal degeneration, is robustly elevated in

Membrane-protein crystals for neutron diffraction

Neutron macromolecular crystallography (NMX) has the potential to provide the experimental input to address unresolved aspects of transport mechanisms and protonation in membrane proteins. However, despite this clear scientific motivation, the practical challenges of obtaining crystals that are large enough to make NMX feasible have so far been prohibitive. Here, the potential impact on feasibilit

Breathing-motion induced interplay effects for stereotactic body radiotherapy of liver tumours using flattening-filter free volumetric modulated arc therapy

The purpose of this study was to investigate breathing-motion induced interplay effects for stereotactic body radiotherapy (SBRT) of liver tumours treated with flattening-filter free (FFF) volumetric modulated arc therapy (VMAT). Ten patients previously treated with liver SBRT were included in this study. All patients had four-dimensional computed tomography (4DCT) scans acquired prior to treatmen

Trends in morbidity : national statistics on sickness claims among the working population in Sweden, 1892–1954

In this article national statistics from Swedish sickness funds are analysed from 1892 to 1954. The study is intended to provide better knowledge of changes in sickness claims, and to contribute to the discussion of morbidity trends. National statistics on sickness benefits are available from 1892, and are studied until the introduction of mandatory health insurance in 1955. Membership of Swedish

A forgotten plague : Dysentery in Sweden, 1750-1900

Dysentery, or rödsot, as the disease was previously known in Sweden, continues to be a major scourge in developing countries. However, the disease has almost disappeared in the West. Very different circumstances prevailed before infectious diseases declined as some of the major causes of death during the 19th century. In that era, 10,000 people could die of dysentery in a single year in Sweden. Th

Low Postseroconversion CD4+ T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection

A positive correlation between virus evolutionary rate and disease progression has been shown for human immunodeficiency virus type 1 (HIV-1) infection. Much less is known about HIV-2, the second causative agent of AIDS. We analyzed 528 HIV-2 env V1-C3 sequences generated from longitudinal plasma samples that were collected from 16 study participants during a median observation time of 7.9 years (

Collective quantum phase slips in multiple nanowire junctions

Realization of robust coherent quantum phase slips represents a significant experimental challenge. Here we propose a design consisting of multiple nanowire junctions to realize a phase-slip flux qubit. It admits good tunability provided by gate voltages applied on superconducting islands separating nanowire junctions. In addition, the gates and junctions can be identical to or distinct from each

AXIN1 in Plasma or Serum Is a Potential New Biomarker for Endometriosis

Although endometriosis is considered an inflammatory disease, no reliable diagnostic biomarkers exist for use in clinical practice. The aim was to investigate the inflammatory profile in endometriosis using an exploratory approach of inflammation-related proteins. Patients with laparoscopy-verified endometriosis (N = 172), women with microscopic colitis (N = 50), healthy controls (N = 31), and age

Implementation of Quiet Areas in Sweden

The notion of quiet areas has received increasing attention within the EU in recent years. The EU Environmental Noise Directive (END) of 2002 stipulates that member states should map existing quiet areas and formulate strategies to keep these quiet. Quiet areas could play an important role in balancing densified urban development by ensuring access to relative quietness and associated health benef

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking behaviour-related traits. We tested up to 235,116 single nucleotide variants (SNVs) on the exome-array for association with smoking initiation, cigarettes per day, pack-years, and sm

Röda skor på kistan : Samspelet mellan mikroriter, trostolkning och livstydning

This article is the author's trial lecture for appointment as Reader in practical theology, held on 3 November 2016. The article is based on the author's own research and practical work with funerals for more than thirty years, but also on secondary research. The article shows the interplay between micro rituals, interpretations of faith, and interpretations of life. The article briefly discusses

Images of the North : An imagological analysis of Nordic noir book covers in Greece and Spain

Although Scandinavia is arguably peripheral in the global literary system, it nevertheless holds a surprisingly prominent position in the field of translation, Swedish and Danish being among the ten most translated languages in the world (Lindqvist, 2015). What literature is selected for translation and introduction into new linguistic contexts is not a coincidence, but has to do with economic fac

Stroke management — recent advances and residual challenges

The past year saw progress in acute treatment of ischaemic stroke, but large inequalities in stroke services were revealed, warranting strategical initiatives to improve treatment access. Reclassification of stroke as a disease of the nervous system in the WHO International Classification of Diseases 11th revision is likely to help such initiatives.

From Mundane to Socially Significant Consumption : An Analysis of How Foodie Identity Work Spurs Market Formation

How does dull turn into cool? Every now and then new markets emerge and consumption that used to be mundane and insignificant transforms into something socially significant. Using the theoretical lens of cultural system transformation, this research set out to analyze how consumers, through their identity work, unintentionally transform a market by negotiating its symbolic boundaries and expanding

Consumer decision-making of slow moving consumer goods in the age of multi-channels

Currently, consumer decision-making is influenced by the spread of technology that has made multi-channel retailing possible. Multi-channel retailing can be defined as a retailer using a combination of separate and independent channels without any overlap for promoting and selling products and services. This study contributes to three research streams: consumer decision-making, multi-channel retai

Combination therapy targeting the elevated interleukin-6 level reduces invasive migration of BRAF inhibitor-resistant melanoma cells

The identification of novel antimetastatic therapeutic targets is necessary for improved treatment of patients with acquired BRAF inhibitor-resistant (BRAFi-R) melanoma, in whom metastasis is a major concern. Our present study focused on the identification of such targets to explore novel antimetastatic therapeutic options for BRAFi-R melanoma patients. We confirmed the development of BRAFi resist