The prognosis for children with high-risk neuroblastoma is often poor and survivors can suffer from severe side effects. Predictive preclinical models and novel therapeutic strategies for high-risk disease are therefore a clinical imperative. However, conventional cancer cell line-derived xenografts can deviate substantially from patient tumors in terms of their molecular and phenotypic features.

Background: Proliferative diabetic retinopathy is a major cause of visual impairment in working-age adults worldwide. Panretinal photocoagulation is a cornerstone in its management; however, it may include a range of side effects and complications, one of these being serous retinal detachment. To the best of our knowledge, this is the first report of the use of intravitreal injection of bevacizuma

Purpose: To examine test–retest reliability and construct validity of the Scandinavian version of the caregiver priorities and child health index of life with disabilities (CPCHILD) questionnaire for children with cerebral palsy (CP). Methods: Families were recruited in Sweden and Norway and stratified according to the gross motor function classification system levels I–V for children born 2000–20

Global comparative studies of the links between economic growth, carbon emissions and ecological footprints as well as social inequality demonstrate that current Western production and consumption patterns and welfare standards are incompatible with environmental limits and IPCC climate targets. To allow for catch-up' development in poorer countries, rich countries would need to ‘degrow’. Against

Summary: The study investigates the effect of physical activity (PA) on a composite score for fracture risk in pre-pubertal children. Low PA in children is related to the composite score for fracture risk and the pre-pubertal years seem to be a period when PA positively affects the score. Introduction: This study evaluates if PA in children is related to clustering of risk factors for fracture. Re

During the winter and spring of 2006, Denmark and Scandinavia faced its most serious crisis since World War II. The conflict started as a Danish newspaper published a number of cartoons, some of which portrayed the prophet Muhammad. After the Danish government rejected their requests to censor the media, Danish Islamists distributed these pictures to some senior political and religious figures in

In the wake of the Orange Revolution, Ukraine has witnessed a substantial growth in organized anti-Semitism. Central to this development is an organization, known as the Interregional Academy of Human Resources, better known by its Ukrainian acronym MAUP. It operates a well-connected political network that reaches the very top of the Ukrainian society. MAUP is the largest private university in Ukr

This paper offers an extensive literature review on the field of Resilience Engineering (RE), encompassing 472 contributions, including journal articles, conference proceedings and book chapters. Adopting the numbers of co-citations as a metric of conceptual proximity, this paper details the application of Factor Analysis and Multi-Dimensional Scaling, as groundbreaking means to extract relevant r

Canadians of Ukrainian descent constitute a significant part of the population of the Albertan capital. Among other things, their presence is felt in the public space as Ukrainian monuments constitute a part of the landscape. The article studies three key monuments, physical manifestations of the ideology of local Ukrainian nationalist elites in Edmonton: a 1973 monument to nationalist leader Roma

Collapse of the Communist system caused similar tendencies in sociopolitical development of the most former Warsaw Pact’s countries, and in particular led to an increase in ethnic nationalism. Mongolia is not an exception among them. Historically, ethnic nationalism was a means of decolonization in Asian countries. Then, in 1990s, it was used for de-Sovietization. In Mongolia, this trend began to