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EULAR Points to Consider (PtC) for designing, analysing and reporting of studies with work participation as an outcome domain in patients with inflammatory arthritis
Background: Clinical studies with work participation (WP) as an outcome domain pose particular methodological challenges that hamper interpretation, comparison between studies and meta-analyses. Objectives: To develop Points to Consider (PtC) for design, analysis and reporting of studies of patients with inflammatory arthritis that include WP as a primary or secondary outcome domain. Methods: The
Late Quaternary Dynamics of Arctic Biota from Ancient Environmental Genomics
During the last glacial–interglacial cycle, Arctic biotas experienced substantial climatic changes, yet the nature, extent and rate of their responses are not fully understood1–8. Here we report a large-scale environmental DNA metagenomic study of ancient plant and mammal communities, analysing 535 permafrost and lake sediment samples from across the Arctic spanning the past 50,000 years. Furtherm
Time to reconsider : Have the 2015 FIGO and 2017 Swedish intrapartum cardiotocogram classifications led us from Charybdis to Scylla?
In 2015, FIGO revised the 1987 intrapartum cardiotocography (CTG) classification (FIGO1987). A less radical FIGO2015 version was introduced in Sweden 2017 (SWE2017). Now, post hoc simulation studies show that FIGO2015 and SWE2017 are less reliable than (a modified) FIGO1987. FIGO2015 shows significantly better interobserver agreement for normal CTG traces than FIGO1987, but significantly worse for
The rapid transition from campus to online teaching–how are students’ perception of learning experiences affected?
The COVID-19 pandemic caused a global disruption to higher education, especially in engineering education, where many teaching and learning activities are difficult or impossible to conduct online. This study examines the changes in the students’ experiences of this disruption using a 26-item process-oriented course experience questionnaire (CEQ) that was already in use in the Faculty of Engineeri
Changing land cover as a driver of surface water browning
Streams, rivers and lakes across wide areas of the Northern hemisphere have been subject to an increase in water color over the last decades. This increase, also known as browning, is a result of rising dissolved organic matter (DOM) and iron (Fe) concentrations in the water. Over the years, browning has received ample attention due to its impact on the structure and function of freshwater ecosyst
The green economy and the Nordic welfare state : Reconceptualizing green economy narratives from a Nordic perspective
The green economy with its aim to combine ecological and economic objectives has gained in both significance and political contestation in recent years. In this working paper for the NOWAGG project we revisit the literature on the green economy to understand its implications from a Nordic perspective. Our ambition is to improve the conceptualization of different approaches to green the economy by
SENSory re-learning of the UPPer limb (SENSUPP) after stroke : development and description of a novel intervention using the TIDieR checklist
Background: Sensorimotor impairments of upper limb (UL) are common after stroke, leading to difficulty to use the UL in daily life. Even though many have sensory impairments in the UL, specific sensory training is often lacking in stroke rehabilitation. Thus, the aim of this paper is to provide a detailed description of the novel intervention “SENSory re-learning of the UPPer limb after stroke (SE
Improvement of platelet respiration by cell-permeable succinate in diabetic patients treated with statins
Diabetes mellitus (DM) is the most severe metabolic disease that reached the level of a global pandemic and is associated with high cardiovascular morbidity. Statins are the first-line lipid- lowering therapy in diabetic patients with or without a history of atherosclerotic disease. Although well tolerated, chronic treatment may result in side effects that lead to treatment interruption. Mitochond
A double-edged sword : Unrecognized cryptic diversity and taxonomic impediment in Eois (Lepidoptera, Geometridae)
The genus Eois Hübner (Geometridae: Larentiinae) comprises 254 valid species. Being a hyperdiverse genus, Eois potentially includes many undescribed cryptic species and embodies a problematic taxonomic scenario. The actual diversity of Eois is greatly underestimated and the Neotropical fauna needs to be well known since it figures as one of the most threatened terrestrial ecosystem. In the present
A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure
The enoyl-acyl carrier protein (ACP) reductase (ENR) is a key enzyme within the bacterial fatty-acid synthesis pathway. It has been demonstrated that small-molecule inhibitors carrying the diphenylether (DPE) scaffold bear a great potential for the development of highly specific and effective drugs against this enzyme class. Interestingly, different substitution patterns of the DPE scaffold have b
Lasting effects of parental death during childhood: evidence from Sweden
This study looks at the effect of losing a parent before the age of 16 on adult income, educational attainment, and health. Using detailed data from the Swedish registers and several methodological strategies, we follow to adulthood individuals born between 1968 and 1981 and observe their later-life outcomes.The results suggest that, in line with previous research, losing a parent during childhood
Variations within simple models for structure-soil interaction
The dynamic response of blocks sitting on a half-space is considered. Buildings and other structures placed on or within the ground influence the transmission of seismic waves. Hence, the presence of a building will have an impact on the dynamic response of neighbouring buildings. Furthermore, obstacles such as concrete blocks lead to wave scattering that may be beneficial or unfavourable for the
Evaluation of Model-Based Iterative Reconstruction in Abdominal Computed Tomography Imaging at Two Different Dose Levels
The purpose of this study was to qualitatively evaluate recently introduced Model-based iterative reconstruction method (IMR) and routinely used iterative reconstruction algorithm iDose4 to investigate future dose reduction possibilities for abdominal CT exams. The study contained data from 34 patients who underwent abdominal CT in SkåneUniversityHospital Lund, Sweden. A low-dose scan (CTDIvol3.4
Echocardiographic assessment of chamber size and ventricular function during the first year after heart transplantation
AIMS: Detecting changes in ventricular function after orthotopic heart transplantation (OHT) using transthoracic echocardiography (TTE) is important but interpretation of findings is complicated by lack of data on early graft adaptation. We sought to evaluate echocardiographic measures of ventricular size and function the first year following OHT including speckle tracking derived strain. We also
Mixed methods assessment of impact on health awareness in adult childhood cancer survivors after viewing their personalized digital treatment summary and follow-up recommendations
Background: The survival rate after childhood cancer has improved to 80%. The majority of childhood cancer survivors (CCS) will experience late complications which require follow up care, including access to their individual cancer treatment summary. The need to understand CCS needs and preferences in terms of ways to receive information e.g. digitally, becomes important. This study aims to throug
Om att möta klimathotet genom att minska antalet människor
Realism of mammography tissue patches simulated using perlin noise : A forced choice reading study
Software breast phantoms are central to the optimization of breast imaging, where in many cases the use of real images would be inefficient - or impossible. Establishing the realism of such phantoms is critical. For this study, patches of simulated breast tissue with different composition - fatty, scattered, heterogenous and dense tissue - were generated using a method based on Perlin noise. The c
Update of clothing database for existing and new Western clothing ensembles, including effects of posture, body and air movement : Report on manikin measurements for ASHRAE 1760-TRP.
ASHRAE Research Project RP-1760 aimed to update thedatabase of western clothing as used in ANSI/ASHRAE Stan-dard 55-2013, Thermal Environmental Conditions for HumanOccupancy (ASHRAE 2013a), ISO Standard 7730-2005,Ergonomics of the Thermal Environment—Analytical Deter-mination and Interpretation of Thermal Comfort Using Calcu-lation of the PMV and PPD Indices and Local ThermalComfort Criteria (ISO
The Nordic Paradox. Professionals’ Discussions about Gender Equality and Intimate Partner Violence against Women in Sweden
Intimate partner violence against women (IPVAW) is a global public health issue often assumed to be associated with gender inequality. The so-called Nordic Paradox, the apparently contradictory co-existence of high levels of IPVAW and of gender equality in Nordic countries, has not been adequately explained. This study explores discussions about how this apparent paradox can be understood among 30