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Carbohydrates are involved in many cellular processes, and most biomolecules are glycosylated. Thesemodifications are used in biological systems as information carriers, helping regulate organization on the cell surfaceand interactions between cells and the environment. Galectins are a family of carbohydrate binding proteins thatbind to polysaccharides containing a galactose. Galectins have the abCarbohydrates are involved in many cellular processes, and most biomolecules are glycosylated. Thesemodifications are used in biological systems as information carriers, helping regulate organization on the cell surfaceand interactions between cells and the environment. Galectins are a family of carbohydrate binding proteins thatbind to polysaccharides containing a galactose. Galectins have the ab

WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Technology for cardiac output (CO) and blood volume measurements has been developed based on blood dilution with a small bolus of physiologic body temperature saline, which, after transcardiopulmonary mixing, is detected with ultrasound sensors attached to an extracorporeal arteriovenous loop using existing

This paper presents measurements of tt¯ production in association with additional b-jets in pp collisions at the LHC at a centre-of-mass energy of 13 TeV. The data were recorded with the ATLAS detector and correspond to an integrated luminosity of 36.1 fb −1 . Fiducial cross-section measurements are performed in the dilepton and lepton-plus-jets tt¯ decay channels. Results are presented at particl

The concentrations of high- and low-density-lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conducted a multi-ancestry genome-wide gene–smoking interaction study in 133,805 individuals with follow-up in an additional 253,467 individuals. Combined meta-analyses identified 13 new loci assoc

The pseudorapidity density of charged particles, d N ch / d η, in p–Pb collisions has been measured at a centre-of-mass energy per nucleon–nucleon pair of sNN = 8.16 TeV at mid-pseudorapidity for non-single-diffractive events. The results cover 3.6 units of pseudorapidity, | η| < 1.8. The d N ch / d η value is 19.1 ± 0.7 at | η| < 0.5. This quantity divided by ⟨ N part ⟩ / 2 is 4.73 ± 0.20 , where

We compared three different Graphical User Interfaces (GUI) that we have designed and implemented to enable human supervision of an unmanned ship. Our findings indicate that a 3D GUI presented either on a screen or in a Virtual Reality (VR) setting provides several objective and subjective benefits compared to a Baseline GUI representing traditional tools.

Numerical dating and geomorphic studies on alluvial sediment were undertaken in the uppermost reaches of the Dunajec River catchment in the northern foreland of the Tatra Mountains of Poland. Successions of alluvial deposits in river terraces and alluvial fans are common in this region. In particular, alluvial fans deposited a thick succession of sediment in the intramontane Orawa-Nowy Targ Depres

Various paleoclimatic records have been used to reconstruct the hydrologic history of the Altiplano, relating this history to past variability of the South American summer monsoon. Prior studies of the southern Altiplano, the location of the world's largest salt flat, the Salar de Uyuni, and its neighbor, the Salar de Coipasa, generally agree in their reconstructions of the climate history of the

Syftet med nuvarande arbetet är att genomföra en klinisk fallstudie som utvärderar begreppet Dynamisk-ElectroEnhanced Chemotherapy ™ (D-EECT). Tio patienter med plavocellkarcinom, åtta med bröstcancer och fem patienter med var och en som presenterade en annan typ av tumör, infördes i försöken initierade av fem olika cancercentra. Alla patienter fick Bleomycin och 2-3 behandlingstider med IQWave ™ The aim of the present work is to perform a clinical case study evaluating the concept of Dynamic-ElectroEnhanced Chemotherapy™ (D-EECT). Ten patients with squamous cell carcinoma, eight with breast cancer and five patients with each presenting a different type of tumour, were entered in the trials initiated by five different cancer centres. All the patients were given Bleomycin and 2 to 3 treatme

Den fackliga organisationsgradens utveckling i Sverige redovisas till och med 2018 (+ uppdatering t o m 2019), det vill säga andelen löntagare som är medlemmar i ett fackförbund. Denna rapport innehåller (1) en grundlig beskrivning av utvecklingen när det gäller organisationsgrad (på både fack- och arbetsgivarsidan), kollektivavtalstäckning och andra förändringar av partsmodellen; (2) en analys av

In this work, we have determined the energy of the S1 state of the carotenoid spheroidene. The energy of this state is 13,400 ± 90 cm-1 at both 293 K and 186 K, showing that there is no temperature-induced shift of the S1 level. A discrepancy of about 800 cm-1 between the S1 energy determined here and that obtained from previous fluorescence and resonance Raman measurements is explained in terms o

A search for Higgs boson pair production in the bb¯ WW * decay mode is performed in the bb¯ ℓνqq final state using 36.1 fb −1 of proton-proton collision data at a centre-of-mass energy of 13 TeV recorded with the ATLAS detector at the Large Hadron Collider. No evidence of events beyond the background expectation is found. Upper limits on the non-resonant pp → HH production cross section of 10 pb a

Inflammatory myofibroblastic tumour (IMT) is a soft tissue tumour primarily affecting children and young adults. Approximately 50% of IMTs have gene fusions involving the receptor tyrosine kinase (RTK)-encoding ALK gene, providing a molecular rationale for treating IMT patients with unresectable tumours with tyrosine kinase inhibitors (TKI). However, a subset of IMT instead displays fusions affect