In recent years, the advent of experimental methods top robe gene expression profiles of cancer on a genome-wide scale has led to widespread use of supervised machine learning algorithms to characterize these profiles. The main applications of these analysis methods range from assigning functional classes of previously uncharacterized genes to classification and prediction of different cancer tiss

Herpes simplex virus (HSV) infected cells express on their surface a receptor with affinity to the Fc portion of immunoglobulin G (IgG). The influence of the infected host cell on the specificity of the receptor was investigated with radiolabeled human IgG Fc fragment and four animal IgGs (rabbit, dog, cow, and rat) and eight human and animal (primate, rabbit, dog, cow, and rat) fibroblastoid and

In this paper streamwise and transverse oscillations of a rigid circular cylinder in a rectangular channel are investigated using the Virtual Boundary method. Numerical study of the three-dimensional flow around the cylinder is done for the uniform Cartesian grid. All computations are performed at Reynolds numbers of Re=500 and 1000 based on the mean flow velocity. The Keulegan-Carpenter number (K

An in-depth photoionization study of the inner-valence electrons in HCl and DCl has been performed using synchrotron radiation. A series of photoelectron spectra of HCl were obtained at a resolution of 23 meV over the binding energy range 25-30.5 eV at various excitation energies and at two different electron collection angles relative to the plane of polarization of the undulator radiation. In ad

S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.

The role of attention in speeded Garner classification of concurrently presented auditory and visual signals was examined in 4 experiments. Within-trial interference (i.e., congruence effects) occurred regardless of the attentional demands of the task. Between-trials interference (i.e., Garner interference) occurred only under conditions of divided attention when making judgments about auditory si

Hypersecretion of airway mucus is a characteristic feature of chronic airway diseases like cystic fibrosis (CF) and leads via impairment of the muco-ciliary clearance and bacterial superinfection to respiratory failure. The major components of the mucus matrix forming family of mucins in the airways are MUC5AC and MUC5B. To investigate the expression of these glycoproteins in CF, immunohistochemis

Popular Abstract in Swedish Automatisk analys av programkod är ett kärnområde inom datavetenskap. Det mest typiska verktyget inom detta område är en kompilator som översätter källkod till maskinkod, men det finns många likartade verktyg, exempelvis översättning mellan språkdialekter, kontroll av kodkonventioner samt automatisk omstrukturering av kod. Eftersom dessa verktyg gör liknande analyser fiProcessing of programs is a core area in computer science. A compiler that translates source text to machine language is the most well-known kind of tool in this area, but there are numerous other kinds of related applications: source-to-source translators, refactoring tools, reengineering tools, metrics tools, consistency checkers, etc. These tools perform similar analyses and can therefore benef

Popular Abstract in Swedish Under det senaste decenniet har föräldrars intresse att välja fristående skolor för sina barn ökat markant. Läsåret 1998-99 gick, enligt Skolverket (1999), drygt 30 000 eller 3 % av grundskolans elever i fristående skolor. Det är emellertid en stor variation mellan landets kommuner. Trots den ringa andel som eleverna i fristående skolor utgör, har diskussionen om skolorAbstract Although the number of children attending private schools in Sweden is less than 4% of those attending compulsory schools, the debate of these schools has been intense. Apart from details as fees and funding, the role of education’ in the Swedish welfare system has been subject of much debate. In spite of the debate, in Sweden there is a lack of knowledge about private schools. The aim of

Individuals identified in the Swedish neonatal alpha1-antitrypsin (AAT) screening study were followed prospectively from their first to their eighteenth year of life. The aim of this study was to analyse the effect of environmental factors, i.e. active and passive smoking, and of clinical factors on lung function and the occurrence of respiratory symptoms in AAT-deficient adolescents. The study gr

A nonlinear dynamic handling model for a tractor-semitrailer combination vehicle is presented in this report. The equations of motion are derived from the fundamental equations of dynamics in Euler's formulation without approximations. The model is modular in the sense that it is easy to change axle configuration, tyre model, suspension model, or to add new features. The primary aim of the model i