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We study the characteristic polynomial pn(x)=∏j=1n(|zj|-x) where the zj are drawn from the Mittag–Leffler ensemble, i.e. a two-dimensional determinantal point process which generalizes the Ginibre point process. We obtain precise large n asymptotics for the moment generating function E[euπIm\,lnpn(r)eaRe\,lnpn(r)], in the case where r is in the bulk, u ϵ R and a ϵ N. This expectation involves an n
This paper discusses how language training for refugees is implemented by the local authorities in Finland and Sweden. The responsibility, production and financing of this specific integration service, language training, is distributed over a multitude of actors in a multidimensional governance structure. We apply a conceptual framework based on intergovernmental relations and conflictual policy p
Direct neural conversion of endogenous non-neuronal cells, such as resident glia, into therapeutic neurons has emerged as a promising strategy for brain repair, aiming to restore lost or damaged neurons. Proof-of-concept has been obtained from animal studies, yet these models do not efficiently recapitulate the complexity of the human brain, and further refinement is necessary before clinical tran
The effective material response as observed at a macro level is a manifestation of the material microstructure and lower scale processes. Due to their distinct atomic arrangement, compared to bulk material, grain boundaries significantly affect the electrical properties of metals. However, a scale-bridging understanding of the associated microstructure–property relation remains elusive so that phe
Aim Heritability of cough has not yet been studied. We aimed to evaluate if individuals with cough are more likely to have offspring who develop cough, and if these associations differ by type of cough (productive/nonproductive). Methods The RHINESSA Generation Study (Respiratory Health In Northern Europe, Spain and Australia) includes 7155 parents (initially aged 30–54) answering detailed questio
Inquiries into properties of brain structure and function have progressed due to developments in magnetic resonance imaging (MRI). To sustain progress in investigating and quantifying neuroanatomical details in vivo, the reliability and validity of brain measurements are paramount. Quality control (QC) is a set of procedures for mitigating errors and ensuring the validity and reliability of brain
This chapter aims to examine the impact of the international anticorruption agenda on the business and investment climate and legal culture in Uzbekistan. In undertaking this task, I specifically emphasise the daily life of anticorruption laws, policies, and agencies in Uzbekistan in order to understand how domestic institutions and actors perceive, interpret, negotiate, and challenge global antic
INTRODUCTION: We aimed to assess the impact of cholinesterase inhibitors (ChEIs) and memantine on cognition, major adverse cardiovascular events (MACE) and mortality in dementia with Lewy bodies (DLB). METHODS: A total of 1,095 incident DLB patients from the Swedish Registry on cognitive/dementia disorders were included. Using an inverse probability of treatment weighting, the effect of initiating
STUDY QUESTION: Can human pre- and peri-pubertal testicular cells obtained from childhood cancer patients, previously treated with chemotherapy, form testicular organoids (TOs)? SUMMARY ANSWER: Organoid formation from testicular tissue collected from childhood cancer patients positively correlates with SRY-Box transcription factor 9 (SOX9) expression in Sertoli cells, which in turn negatively corr
Introduction: Infective endocarditis (IE) is a challenging diagnosis to suspect and to confirm. The purpose of this study was to clarify how often IE is suspected already on hospital admission, which clinical signs trigger the physicians’ suspicions and to investigate if the empirical treatment is adequate. Methods: A retrospective observational study of cases with definitive IE, during 2018–2019
Functional amyloids formed by the protein FapC in Pseudomonas bacteria are key structural components of Pseudomonas biofilms, which mediate chronic infections and also contribute to antimicrobial resistance. Here, we combine kinetic experiments with mechanistic modelling to probe the role of surfaces in FapC functional amyloid formation. We find that nucleation of new fibrils is predominantly hete
Background and objective: This publication represents a summary of the updated 2024 European Association of Urology (EAU) guidelines for non–muscle-invasive bladder cancer (NMIBC), TaT1, and carcinoma in situ. The information presented herein is limited to urothelial carcinoma, unless specified otherwise. The aim is to provide practical recommendations on the clinical management of NMIBC with a fo
Lead-free hybrid metal halide phosphors/crystals showing self-trapped exciton (STE) emission have been recently explored for thermography due to the strong temperature dependence of their photoluminescence (PL) lifetime (τ). However, realizing high-spatial-resolution thermography using polycrystalline powders or crystals presents a challenge. Moreover, the underlying mechanism of temperature-depen
The quality of lake ice is of uppermost importance for ice safety and under-iceecology, but its temporal and spatial variability is largely unknown. Here weconducted a coordinated lake ice quality sampling campaign across theNorthern Hemisphere during one of the warmest winters since 1880 and showthat lake ice during 2020/2021 commonly consisted of unstable white ice, attimes contributing up to 10
The future of AIS conferences, thrown into sharp relief by virtual innovations during the pandemic and the subsequent return to face-to-face conferences, is debated in this special issue. This editorial introduces the seven papers contained in the special issue and provides the context for the debate on the future of conferences in the AIS Community as well as pinpointing key contributions made by
