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Higher plasma IL-6 and PTX3 are associated with worse survival in left heart failure with pulmonary hypertension

Introduction: Left heart failure (LHF) is commonly complicated by pulmonary hypertension (PH), increasing morbidity and mortality. The present study aimed to evaluate the prognostic value of inflammatory proteins in LHF with PH (LHF-PH). Materials and methods: The levels of 65 plasma proteins, analysed with proximity extension assay, were compared between healthy controls (n = 20), patients with L

Swedish occupational therapists’ views and experiences regarding use of the ADL-taxonomy in clinical practice.

Bakgrund: Enligt klinisk forskning visar ADL-taxonomin hög validitet och reliabilitet, men det finns inga studier kring svenska arbetsterapeuters erfarenheter av att använda ADL-taxonomin som bedömningsinstrument i sitt kliniska arbete. Det är viktigt att studera användarnas erfarenheter och synpunkter för att förbättra implementering av evidensbaserade metoder såsom ADL-taxonomin. Syfte: SyfBackground: The ADL-taxonomy as an assessment instrument shows high validity and reliability in the clinical research, but there is no study about occupational therapists’ experiences of using the ADL-taxonomy in clinical practice. It is important to study the users’ experiences and views to improve implementation of evidence-based methods such as the ADL-taxonomy. Aim: The aim of this study i

Begreppet rättssäkerhet och betydelsen av begreppet i den offentliga debatten om anonyma vittnen

Frågan om anonyma vittnen har länge varit föremål för debatt i den juridiska världen. Är det en rättssäker åtgärd att införa ett system med anonyma vittnen? Hur skulle ett sådant system, om det infördes, överensstämma med de rättssäkerhetsgarantier som tillstår den tilltalade i rättsprocessen? Tidigare forskning kring anonyma vittnen har fokuserat på rättssäkerheten och försökt nå en slutsats krinThe issue on anonymous witnesses has in Sweden been frequently discus-sed in the legal debate over the years. Is it according to the rule of law to impose such a system? How does a system of anonymous witnesses con-form with the principles of the rule of law given to the accused during a hearing? Past research has centered the discussion around the rule of law and the effects an imposition of a sy

Karyatider. Kontext, funktion och innebörd från arkaisk till hellenistisk tid.

This paper examines caryatides in Greek architecture from the Archaic period to the Hellenistic period. The focus of this study is the functions, contexts, and symbolic meanings of the caryatides. Regarding the contexts, the caryatides were first used in the archaic period on the Cnidian treasury and, shortly thereafter on the Siphnian treasury, both in Delphi. In the classical period, the caryati

Röekillorna unsealed – an osteological analysis of the seal remains at Röekillorna Spring

Zooarchaeological studies have played a crucial role in understanding the pre-historic societies of Scania. The analysis of animal remains from archaeological sites has provided insights into the subsistence strategies, economic practices, and cultural beliefs of the people who lived in the region. Remains from horse, dog, wild boar, and man are commonly observed in offering and burial contexts. D

Canossa Castle and Azuchi Castle: A comparative study of the castle-building phenomenon in Italy and Japan

This thesis aims at evaluating the castle-building phenomenon in Italy and Japan through a comparative study of Canossa Castle in Italy and Azuchi Castle in Japan. By comparing Canossa Castle and Azuchi Castle, this thesis firstly investigates the definition of the word castle in Italian, Japanese and English to understand how languages influence the understanding of this phenomenon. By using pr

Between a Rune Stone and a Hard Place: Deconstructing Mass Media Influence on Knowledge Production in Viking Age Archaeogenetic Publications

The archaeological traditions of the Viking Age have a complex history. Some of it has been nationalist in orientation, at times constructing proud historical narratives reflecting ownership in and continuity of the past. These narratives conflict with increasing population diversity in the Scandinavian nations, where contemporary identity politics grapple with real and imagined realities of im

Arbetsterapeuters samkonstruktion med barn med autismspektrumdiagnos för att främja deras delaktighet i interventioner

Bakgrund: Barn ska få vara delaktiga och få anpassat stöd för att uttrycka sig i sin intervention. Barn med autismspektrumdiagnos (ASD) har ofta en annorlunda sensorisk process, vilket kan påverka delaktighet i aktiviteter. Det saknas information kring hur arbetsterapeuter samkonstruerar med barnet som klient i interventioner. Syfte: Att undersöka hur arbetsterapeuters samkonstruktion sker med barBackground: Children must receive tailored support to participate and express themselves in their care. Children with autism spectrum disorder (ASD) commonly have a different sensory process, which can affect participation in activities. There is a lack of information regarding how occupational therapists collaborate with children as clients in interventions. Purpose: To investigate how occupation

Early onset ataxia with comorbid myoclonus and epilepsy : A disease spectrum with shared molecular pathways and cortico-thalamo-cerebellar network involvement

OBJECTIVES: Early onset ataxia (EOA) concerns a heterogeneous disease group, often presenting with other comorbid phenotypes such as myoclonus and epilepsy. Due to genetic and phenotypic heterogeneity, it can be difficult to identify the underlying gene defect from the clinical symptoms. The pathological mechanisms underlying comorbid EOA phenotypes remain largely unknown. The aim of this study is

GlassesValidator : A data quality tool for eye tracking glasses

According to the proposal for a minimum reporting guideline for an eye tracking study by Holmqvist et al. (2022), the accuracy (in degrees) of eye tracking data should be reported. Currently, there is no easy way to determine accuracy for wearable eye tracking recordings. To enable determining the accuracy quickly and easily, we have produced a simple validation procedure using a printable poster

Commentary on "Fatal cardiac air embolism after CT-guided percutaneous needle lung biopsy medical complication or medical malpractice?"

To differentiate between medical malpractice and expected, but rare, medical complication in a medicolegal autopsy context is often difficult. Such an assessment requires knowledge about the clinical practice associated with the procedure at hand, and that findings of the autopsy, including medical relevant information such as patient chart, radiological imaging, and statements from witnesses abou

Incorporating Sustainability into Organizational Culture: An Exploration of Challenges and Solutions in the Swedish Banking Sector

Sustainability has emerged as a critical aspect of business operations globally, encompassing environmental impact, social responsibility, and governance factors. With its ability to allocate financial resources, the banking sector plays a unique role in achieving global sustainability goals. This makes it vital for banks to prioritize sustainability and embed it as a core value due to customer de

Sociala normer rörande sexualitet i kvinnors personliga berättelser

The aim of this study was to explore how personal stories describe social norms when speaking of sexuality. Data was collected through a qualitative thematic analysis of the book Flickan och skammen written by Katarina Wennstam. The book contains six personal stories of women who have been exposed to sexual violence at some point in their life. The results of the study show that social norms have

"Det är ett annat Skellefte" - En socialantropologisk studie om skelleftebornas hem i förändring

I Skellefteå sker i dagsläget en omfattande samhällsomvandling till följd av nya befolkningsmål och etableringen av bilbatterifabriken Northvolt. Det ställs därför höga krav på den sociala infrastrukturen med avseende på intensiteten i omvandlingen, något som väcker frågor om stadens förmåga att utvecklas socialt hållbart och omvandlingens påverkan på lokalbefolkningen. Syftet med uppsatsen ämnar

Kvasiregeringen och dess medborgare: En socialantropologisk studie om kåren och programföreningarna vid Samhällsvetenskapliga fakulteten

This study explores the dynamics between the student union and programme associations at Lund University's Faculty of Social Sciences. Examining the perspectives of programme association representatives on the union and themselves, it investigates the union's challenges, the political tensions between the organisations and the way in which they may serve as a microcosm reflecting broader s

"Det här är inte ditt fel och vi ska lägga ansvaret där det behöver ligga" - En diskurspsykologisk analys av de professionellas tal om ungdomar med kopplingar till kriminalitet och ansvar för målgruppen

The aim of this thesis is to examine the professionals’ views on young offenders and responsibility for the target group. We have chosen to interview social workers who work within the public sector and have direct contact with young offenders. Discursive psychology was used to analyse our empirical material in order to highlight the interpretative repertoires permeating through the professionals’

"Ibland kan vi inte göra det jobbet vi behöver göra, ska göra och måste göra" - En kvalitativ intervjustudie om desinformationskampanjen som påstår att socialtjänsten tar barn och dess påverkan på socialsekreterares arbete

The aim of this study was to explore how Swedish social workers were affected by the disinformation campaign claiming that social services take children. The study explored how social workers were affected by this in their work revolving around meetings with clients and assessments. We used a qualitative method with semi-structured interviews. The result is based on interviews with seven Swedish s

Role of serotype and virulence determinants of Streptococcus pyogenes biofilm bacteria in internalization and persistence in epithelial cells in vitro.

Streptococcus pyogenes causes a multitude of local and systemic infections, the most common being pharyngitis in children. Recurrent pharyngeal infections are common and are thought to be due to the re-emergence of intracellular GAS upon completion of antibiotic treatment. The role of colonizing biofilm bacteria in this process is not fully clear. Here, live respiratory epithelial cells were inoc

In Vivo Profiling of the Vascular Cell Surface Proteome in Murine Models of Bacteremia

Vascular dysfunction is a hallmark of systemic inflammatory responses such as bacterial sepsis. The luminal surface of the blood vessels is coated with a dense layer of glycans and proteoglycans, collectively known as the glycocalyx. Surface associated glycoproteins of endothelial origin, or derived from pericytes, intravascular leukocytes, and plasma, are other important components of the glycoca