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The most abundant plasma protein, human serum albumin (HSA), plays a key part in the body's antioxidant defense against reactive species. This study was aimed at correlating oxidant-induced chemical and structural effects on HSA. Despite the chemical modification induced by the oxidant hypochlorite, the native shape is preserved up to oxidant/HSA molar ratio <80, above which a structural transitio

The summed probability distribution of 162 radiocarbon dates from Gotland was analysed with reference to archaeological and environmental data in order to evaluate possible variations in settlement intensity on the island. The data indicated variations in demographic development on the island, with probably several different colonization events and external influences; the pioneer settlement reach

Gender inequality in human capital has been shown to be an important indicator of economic development, but has remained unexplored in a European history perspective. Using a new and large historical database on male and female literacy rates, new evidence is presented on the distribution of gender inequality in human capital in European regions in 1900 and 1960. An analysis is made of the distrib

Rapid climate warming has resulted in shrub expansion, mainly of erect deciduous shrubs in the Low Arctic, but the more extreme, sparsely vegetated, cold and dry High Arctic is generally considered to remain resistant to such shrub expansion in the next decades. Dwarf shrub dendrochronology may reveal climatological causes of past changes in growth, but is hindered at many High Arctic sites by sho

Rapporten är ett resultat av ett forskningsprojekt ”Fornsaker med landskapsarkeologiska perspektiv på Kullen” finansierat av Gyllenstiernska Krapperupstiftelsen 2015-2016. Det övergripande syftet var att beskriva och analysera fornsakssamlingen på Krapperup med avseende på föremålstyper, fyndplatser och fyndomständigheter. Accessionen av föremål skedde på initiativ baronen Carl Gyllenstierna främs

OBJECTIVE: To explore and quantify the relative strengths of the genetic contribution vs the contribution of modifiable environmental factors to severe osteoarthritis (OA) having progressed to total joint arthroplasty.DESIGN: Incident data from the Norwegian Arthroplasty Registry were linked with the Norwegian Twin Registry on the National ID-number in 2014 in a population-based prospective cohort

OBJECTIVE: To explore factors related to hand pain in persons with radiographic hand osteoarthritis (OA).METHODS: Persons in the Musculoskeletal Pain in Ullensaker Study with radiographic hand OA (≥1 joint with Kellgren/Lawrence grade ≥2) were included (n = 530). We examined the cross-sectional association between possible explanatory variables and hand pain in the entire sample and in 2 hand OA p

BACKGROUND: Widespread musculoskeletal pain (WSP) and obesity frequently co-occur and may have shared risk factors. We aimed to investigate whether four dichotomized risk factors individually or jointly increase the risk for the onset of WSP and onset of obesity.METHODS: Persons aged 34-76 years in 2004 living in Ullensaker municipality, Norway, responded to questionnaires in 2004 and 2010 (n = 15

Background: Production of second-generation bioethanol and other bulk chemicals by yeast fermentation requirescells that tolerate inhibitory lignocellulosic compounds at low pH. Saccharomyces cerevisiae displays high plasticitywith regard to inhibitor tolerance, and adaptation of cell populations to process conditions is essential for reachingefficient and robust fermentations.Results: In this stu

Mining, seen as a source of revenue in most developing countries, threatens seriously the environment. Mining impacts the water quality and one of the main problems of mining is acid mine drainage. Low pH and high concentration of heavy metals characterize acid mine drainage. When a stream is impacted by acid mine drainage both human activities and the ecological system are seriously affected. In