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Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix.

Components derived from cartilage have been suggested to maintain the inflammation in joints in arthritis. Small leucine-rich repeat proteins (SLRPs) are structural components of cartilage important in organizing the meshwork of extracellular matrix components. It has recently been shown that the SLRP fibromodulin interacts with complement initiator C1q, leading to complement activation. The compl

Livsstil och livsföring i Simmels och Webers klassiska sociologi

Artikeln diskuterar hur begreppen livsstil och livsföring introducerades i sociologin. Bland annat visas på att begreppet livsstil intorducerades på bred front av Simmel i "Philosophie des Geldes" (1900). Avslutningsvis diskuteras några möjliga användningar av begreppen idag.

Hepatocellular Carcinoma Risk Factors and Disease Burden in a European Cohort: A Nested Case-Control Study.

Background: To date, no attempt has been made to systematically determine the apportionment of the hepatocellular carcinoma burden in Europe or North America among established risk factors.MethodsUsing data collected from 1992 to 2006, which included 4 409 809 person-years in the European Prospective Investigation into Cancer and nutrition (EPIC), we identified 125 case patients with hepatocellula

Incidence and survival rates in Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa.

Objective. To estimate the incidence of and survival rates for WG, microscopic polyangiitis (MPA), Churg-Strauss syndrome (CSS) and PAN within a defined population in southern Sweden. Methods. Cases were retrieved using hospital records and a serology database. All new cases of WG, MPA, CSS and PAN between 1997 and 2006 were included, provided they met pre-defined criteria, and were followed until

Freezing of Gait Questionnaire: validity and reliability of the Swedish version.

Background - Patient-reported assessments of freezing of gait (FOG) in Parkinson's disease (PD), such as the FOG questionnaire (FOGQ), are needed because FOG is difficult to assess objectively. However, the measurement properties of the FOGQ have been sparsely assessed. Aim - To assess the measurement properties of the Swedish FOGQ, and to explore relationships between FOGQ scores and other aspect

Menisk- och korsbandsskador

The treatment of meniscus tears and anterior cruciate ligament (ACL) injuries are mainly considered as symptomatic. Meniscus tears can be divided into traumatic and degenerative tears, with different outcomes. A displaced meniscus with a locked knee constitutes an acute indication for arthroscopic surgery. A degenerative tear with mechanical symptoms also represents an indication for surgery. The

Sources of increase in lowermost stratospheric sulphurous and carbonaceous aerosol background concentrations during 1999-2008 derived from CARIBIC flights

This study focuses on sulphurous and carbonaceous aerosol, the major constituents of particulate matter in the lowermost stratosphere (LMS), based on in situ measurements from 1999 to 2008. Aerosol particles in the size range of 0.082 mm were collected monthly during intercontinental flights with the CARIBIC passenger aircraft, presenting the first long-term study on carbonaceous aerosol in the LM