Optimization of an engineered IgG binding protein domain with calcium dependent behavior for mild antibody purification
Antibodies have become immensely important reagents within biomolecular research and analysis as well as in medicine. Monoclonal antibodies are the largest class of biological drugs and with an increasing number of therapeutic antibodies approved for clinical use the need for efficient purification strategies is vast. Today, most antibodies are purified using affinity chromatography based on Prote
