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B-1a cells are innate-like lymphocytes that develop primarily during fetal and neonatal life, whereas adult bone marrow (BM) hematopoietic stem cells (HSCs) preferentially give rise to follicular B-2 cells. Functioning at the interface of the innate and adaptive immune systems, B-1a cells provide a non-redundant first line of defense prior to the temporally delayed establishment of a B-2 cell resp
In this paper, we present a study for the identification of stancerelated features in text data from social media. Based on our previous work on stance and our findings on stance patterns, we detected stance-related characteristics in a data set from Twitter and Facebook. We extracted various corpus-, quantitative- and computational-based features that proved to be significant for six stance categ
Bakteriesläktet Aerococcus består av åtta arter av s.k. Grampositiva kocker. Den första arten, A. viridans, beskrevs 1953 och kopplingar gjordes mellan den och en allvarlig sjukdom hos hummer. Det skulle dröja åtskilliga decennier innan nästa aerokockart, A. urinae, upptäcktes. Denna kopplades till urinvägsinfektioner (UVI) och bakteriemi, dvs. växt av bakterier i blodet, hos människa. Därefter haThe genus Aerococcus comprises eight species of Gram-positive cocci. The incidence and the clinical importance of aerococcal infections have been underestimated in the past, due to species identification difficulties. In our first study, we evaluated the usefulness of MALDI-TOF MS as a species identification method for aerococci and found that it had a high sensitivity and specificity. Two populat
Glucocorticoid treatment, a major cause of drug-induced osteoporosis and fractures, is widely used to treat inflammatory conditions and diseases. By contrast, mechanical loading increases bone mass and decreases fracture risk. With these relationships in mind, we investigated whether mechanical loading interacts with GC treatment in bone. Three-month-old female C57BL/6 mice were treated with high-
Circulating vitamin B6 levels have been found to be inversely associated with lung cancer. Most studies have focused on the B6 form pyridoxal 5′-phosphate (PLP), a direct biomarker influenced by inflammation and other factors. Using a functional B6 marker allows further investigation of the potential role of vitamin B6 status in the pathogenesis of lung cancer. We prospectively evaluated the assoc
Background: Diastolic dysfunction (DD) is increasingly common. However, its metabolic determinants are poorly known. This study aims to determine which metabolic and inflammatory features predict DD in initially healthy adults. Methods: We prospectively analyzed the association between metabolic features and DD in 728 initially healthy adults aged 30–60 from Eastern France enrolled in the STANISLA
Background: Participation in everyday life and society is generally seen as essential for health-related outcomes and acknowledged to affect older people’s well-being. Aims: To investigate if aspects of performance- and togetherness-related participation influence on mortality among very old single living people in Sweden. Methods: ENABLE-AGE Survey Study data involving single-living participants
Objective: To explore conditions influencing long-term participation in social and leisure activities among people who have had a stroke. Methods: This study had a qualitative design, using a grounded theory methodology. Data collection was based on in-depth interviews performed 15 years after a first-ever stroke with 10 persons recruited from a population-based stroke cohort in Sweden. The study
Background: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy might be an optional treatment, through desensitization to egg allergen. Objectives: To determine the efficacy and safety of oral and sublingual immunotherapy in children and adults with immunoglobulin E (IgE)-mediated egg allergy as compared to a placebo treatmen
Background: As a renewable energy solution, photovoltaics (PVs) are crucial in the transition to a more sustainable energy system. Besides large PV installations, household adoption of PVs will be an important contribution to this transition. However, the adoption of PVs on a household level faces many barriers, with gathering and understanding information being one of the major barriers. The aim
Summary: The Fracture Liaison Service (FLS) Consensus Meeting endorsed by the International Osteoporosis Foundation (IOF), Asian Federation of Osteoporosis Societies (AFOS), and Asia Pacific Osteoporosis Foundation (APOF) was hosted by the Taiwanese Osteoporosis Association on October 14, 2017. International and domestic experts reviewed the 13 Best Practice Framework (BPF) standards and concluded
The deactivation of a diesel SCR (Selective Catalytic Reduction) catalyst by impregnation with CaSO4 was studied. The loss in activity after 2729 h of use on the engine was lower than when deactivated by impregnation. This was the case even if the amount of Ca in the catalyst was high after use on the engine. In the used catalyst a surface layer of CaSO4 was built up on the monolith during use. Th
