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Path-Planning Algorithms for a Levitating Planar Motion System

Multi-agent pathfinding (MAPF) is becoming increasingly interesting because of its role in complex systems, such as warehouse sorting, search-and-rescue missions and autonomous vehicles. Another application for path planning is within production in industry when more advanced solutions than conveyor belts are developed. One such advanced transportation system is the XPlanar system, which is produc

Amide functionalization of sialic acid – a synthesis towards kinetic studies

Sialinsyra är ett samlingsnamn för enkla sockerarter som har en ryggrad bestående av 9 kol, med bland annat en karboxylsyra och en glycerolsvans. Sialinsyra förekommer naturligt i kroppen hos däggdjur. Hos människan är Neu5Ac den mest förekommande sialinsyran, och när man refererar ospecifikt till sialinsyra brukar det vara Neu5Ac som avses. Neu5Ac går att hitta i änden av de kolhydratkedjor som Sialic acids are a family of 9-carbon sugars which contain a carboxyl group and a glycerol chain. Neu5Ac is the most common sialic acid in humans and occurs at the terminal position of glycoconjugates covering the cell surface. Neu5Ac is involved in several different processes in the human body and plays an important role in several physiological conditions and pathogenic diseases. Sialic acid is

Vässla – The Cost of Ambition

This case explores the rise and challenges of Vässla, a Swedish electric micromobility startup that positioned itself as a premium, sustainable alternative to gas-powered scooters. Despite strong brand differentiation, consumer demand, and initial success, Vässla faced operational difficulties and financial instability. Set in 2019, this case challenges students to assess whether Vässla’s brand st

Machine Learning for Mortality Risk Prediction: A Study on Cohort Data

This thesis explores the application of machine learning techniques to predict mortality risk using data from the Swedish Adoption/Twin Study of Aging (SATSA). Through the development and evaluation of multiple supervised learning models, including Random Forest and Histogram Gradient Boosting classifiers, the study examines mortality predictors across 10-year and 20-year timeframes. The models ac

Method Development for PKM2 Activity Analysis in Cancer-Associated Signaling Pathways

Introduction: PARP14 belongs to the superfamily of PARPs that perform ADP-ribosylation of target proteins. The enzyme is involved in many cellular processes, including regulation of glycolysis, protein degradation, and genomic reparation. Background: PKM2 has been shown to be regulated indirectly by PARP14 to promote the Warburg effect. This describes an alternative glycolysis that cancer cells a

Attityder till ADHD i socialt arbete: en kvalitativ analys

This study focuses on attitudes towards ADHD in social work amongst social workers diagnosed with ADHD, their managers, and their colleagues. The study consists of six semi-structured interviews, done mostly over video calls. Two of the participants are social workers diagnosed with ADHD and four of the participants are managers who have co-workers that have been diagnosed with ADHD. The result ha

Motstridigheter i handlingsutrymmet - Yrkesverksamma socialarbetares upplevelser i arbetet med papperslösa klienter

This study aims to gain knowledge about social workers' experience of their work with undocumented clients and their perception of their room of action about their experiences with this client group. The study is of qualitative orientation and it’s been carried out through semi-structured interviews. The interviews were carried out with five social workers in different workplaces including non

Design and synthesis of 1,3-functionalized 2-propanol derivatives towards small blood-brain barrier permeable galectin-3 inhibitors

De senaste 50 åren har antalet äldre i det svenska samhället mer än fördubblats. Trenden är densamma runtom i världen - människor lever generellt längre nu än förr. Samtidigt som vi får glädjas över att få spendera mer tid med våra älskade innebär denna högre ålder samtidigt en ökad risk för vissa sjukdomar. En av dessa åldersrelaterade sjukdomar är demens, vilket idag ca 140 000 personer i SverigIn 2022, approximately 32 million patients worldwide suffered from Alzheimer’s disease dementia. In addition to this, about 380 million people carried the biomarkers indicating Alzheimer’s, while displaying little to no symptoms. These people, however, always live with the risk of the disease progressing - making the development of a drug that can slow down or stop progression an endeavour of glob

Kyrkan som "försvann"

I ett av världens mest sekulariserade länder, Sverige, har kyrkans historia och närvaro lämnat tydliga spår i våra städer och på vår landsbygd. Det kollektiva samhället och den kyrkliga gemenskapen har i stor utsträckning ersatts av individualism, vilket har bidragit till att förändra kyrkans roll och funktion. Kyrkan, och dess förutsättningar att bedriva verksamhet, står idag inför vissa utmaning

"Jag skulle bara vilja ta med dig hem och bara ta hand om dig" - En kvalitativ studie om känslomässiga utmaningar och hanteringsstrategier på kvinnojourer i Sverige

There are numerous women’s shelters in Sweden that offer protection and support to female victims of domestic violence. The purpose of this study was to investigate the emotional challenges faced by professionals working in these shelters, which may affect their performance and well-being. The study aimed to identify methods of promoting effective professional work and preventing emotional burnout

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This thesis begins by briefly discussing translation in general, identifying some of the problems involved in the linguistic activity. Then it seeks to explain what is involved in translation relating to film and television, i.e. subtitling. Finally, a comparison will be made between the Spanish speech in the Mexican film, Como agua para chocolate - directed by Alfonso Arau in 1992 and based on hi

Incestens påverkan på kvinnors relationer och självkänsla

Incest against children is a widespread social problem as it causes extensive psychological and physical harm to the child. Previous research has shown that the most harmful form of incest is the one that occurs between fathers and daughters. Therefore, this study aimed to investigate women's experiences of being subjected to incest and how it has affected their relationships and self-esteem.