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Update to RIFM fragrance ingredient safety assessment, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol, CAS Registry Number 67801-20-1
Subtypes of Alzheimer's disease : questions, controversy, and meaning
The distribution of Alzheimer's disease (AD) tau pathology varies systematically and causes a diverse array of syndromes. This forum article provides a brief overview of key controversies in untangling the complexity of AD subtypes, explores potential causes of AD variability in the population, and discusses clinical relevance and future directions of research into AD heterogeneity.
RIFM fragrance ingredient safety assessment, trans-2-nonenal, CAS Registry Number 18829-56-6
Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure
The novel coronavirus SARS-CoV-2, which emerged in late 2019, has since spread around the world and infected hundreds of millions of people with coronavirus disease 2019 (COVID-19). While this viral species was unknown prior to January 2020, its similarity to other coronaviruses that infect humans has allowed for rapid insight into the mechanisms that it uses to infect human hosts, as well as the
Towards an Integration of Research on Teaching and Learning
ABSTRACT: The aim of this article is to present arguments for an integrated empirical research on teaching and learning based on previous research and the phenomenographic research tradition. From 1970 and for some years after, the main focus in phenomenographic research was on students’ approaches to and understanding of subject matter. Later, based on Variation theory and in the form of Learning
ICC Commentary: Article 8(2)(e)(viii)
ICC Commentary: Article 8(2)(e)(xii)
Self-employment : The significance of families for professional intentions and choice of company type
Purpose – The purpose of this paper is to examine the influence that family factors have on an individual’s intention to be self-employed. Design/methodology/approach – The authors selected, from Swedish national registers, all full siblings born between 1945 and 1960 and their biological children, who were born before 1985. The authors created one family database consisting of male individuals (n
A multi-surface model for ferroelectric ceramics - Application to cyclic electric loading with changing maximum amplitude
Depending on the maximum amplitude of externally applied cyclic electric fields, ferroelectric ceramics show minor or major hysteresis. The materials also show asymmetric butterfly hysteresis in a prepoled material. Aiming at capturing these behaviour in a phenomenological constitutive model, a multi-surface modelling approach for ferroelectrics is introduced. In this paper, with the note on the m
Interaction between pH and Cu toxicity on fungal and bacterial performance in soil
pH is an important parameter affecting heavy metal toxicity in soil. Bacterial and fungal growth, and respiration, during 60 days were determined in response to Cu additions (up to 32 mmol Cu kg-1 soil) in four soils with pH varying between 4.5 and 7.8. We hypothesized that at higher pH the toxic effect of Cu would decrease. In soil with pH 7.8, no negative effects on microbial growth were found u
A planning process map for solar buildings in urban environments
Our future built environment will not only consume energy, it will also produce (partly) its own energy need. Solar energy has been proven to be a valid strategy for producing on-site renewable energy. Planning for integrating solar energy in buildings involves many players and decision-making. In this article, a process map defining which decisions regarding solar energy needs to be discussed in
Duty to Prosecute or Extradite: Reflections on the Basis of States' Obligations Stemming from Violations of Jus Cogens Norms
The obligation to prosecute or extradite is a growing sensitive issue in international law. In the recent case Questions Relating to the Obligation to Prosecute or Extradite (Belgium v. Senegal), the International Court of Justice was confronted with determining a breach to the obligation to prosecute or extradite in relation to acts of torture set forth in Article 7(1) of the 1984 UN Convention A
In silico physicochemical characterization and comparison of two intrinsically disordered phosphoproteins : β-casein and acidic PRP-1
A coarse-grained model has been implemented using the Metropolis-Hastings Monte Carlo method to simulate β-casein and acidic proline-rich protein 1 (PRP-1). The aim of the study is to directly compare the properties and behavior of β-casein and PRP-1, in both bulk solution and in the presence of a negatively charged surface, in order to evaluate the possibility of using β-casein as a replacement f
The multielectron character of the S 2p → 4eg shape resonance in the SF6 molecule studied via detection of soft X-ray emission and neutral high-Rydberg fragments
We have studied the nature of the S 2p → 4eg shape resonance in the SF6 molecule by performing two different experiments. Soft X-ray emission spectra measured at the 4eg shape resonance reveal features that do not originate from the S 2p-1 states. One of the features can be assigned to the 6a1g → S 2p transition. The 6a1g orbital, which is empty in the molecular ground state, can be populated eith
Judicial Dialogue and the Making of International Law
A Dimension-Breaking Phenomenon for Water Waves with Weak Surface Tension
It is well known that the water-wave problem with weak surface tension has small-amplitude line solitary-wave solutions which to leading order are described by the nonlinear Schrödinger equation. The present paper contains an existence theory for three-dimensional periodically modulated solitary-wave solutions which have a solitary-wave profile in the direction of propagation and are periodic in t
Combinations of cereal β-glucans and probiotics can enhance the anti-inflammatory activity on host cells by a synergistic effect
The influence of oat and barley β-glucans on some features of diverse probiotic strains was investigated. Neither barley nor oat β-glucans supported the growth of any of the investigated strains when used as the sole carbon source in fermentation media. No protective effect by β-glucans was observed on bacterial survival to in vitro simulation of the human digestive tract. Moreover, the presence o
Combining the parabolic synthesis methodology with second-degree interpolation
The Parabolic Synthesis methodology is an approximation methodology for implementing unary functions, such as trigonometric functions, logarithms and square root, as well as binary functions, such as division, in hardware. Unary functions are extensively used in baseband for wireless/wireline communication, computer graphics, digital signal processing, robotics, astrophysics, fluid physics, games
The continental Si cycle and its impact on the ocean Si isotope budget
The silicon isotope composition of biogenic silica (δ30SiBSi) in the ocean is a function of the δ30Si of the available dissolved Si (DSi; H2SiO4), the degree of utilisation of the available DSi, and, for some organisms, the concentration of DSi. This makes δ30SiBSi in sediment archives a promising proxy for past DSi concentrations and utilisation. At steady-state, mean δ30SiBSi must equal a weight