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Structural and physicochemical studies on metal and porphyrin binding by the Bacillus subtilis ferrochelatase

The enzyme ferrochelatase (EC 4.99.1.1) is the terminal enzyme in the biosynthetic pathway of heme b and catalyzes the insertion of Fe(II) into protoporphyrin IX. In this dissertation ferrochelatase from Bacillus subtilis was studied. A new purification method via inclusion bodies was developed that enabled simple purification of recombinant enzyme without tags or modifications that might affect t

The Generalized Signal Detection Theory

Signal detection theory (SDT) and the Dual Process SDT (Yonelinas, 1994) are currently the most influential accounts of item variability in recognition memory. However, neither provides a sufficient account of differences in the familiarity distributions. Instead, this phenomenon is accounted for by the idea of encoding variability (Wixted, 2007) or an additional retrieval process (Yonelinas, 2001

Cooling vest incorporated with phase change materials (PCMs): how much benefit is there?

The aim of this study was to investigate torso cooling benefit of various PCM vests in a simulated warm environment (Ta= 34 °C, RH=56 %, Va=0.4 m/s). A pre-wetted cotton torso fabric skin was used to simulate sweating on a thermal manikin (Tmanikin=34 °C). Six conditions were tested: nude fabric skin (Fabric Skin), Vest A without (VA) and with frozen gels with a melting temperature (Tm) of 0 °C (V

Process Control—Past, Present, and Future

This paper gives a perspective on the development of process control from the early development and the emergence of the automation industry to today's computer-controlled systems. Some speculations on future developments are also given.