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Every year, approximately 1 million new colorectal cancer (CRC) cases are diagnosed and about half a million people worldwide die due to this cancer. Known differences in CRC incidence rates are mainly attributed to differences in diet and other environmental factors represented, among others, by nutrition-related complex diseases (e.g. obesity and diabetes mellitus type II). Within the last years
BACKGROUND: Exposure to perfluorooctane sulfonate (PFOS) may potentially disturb fetal Leydig cell hormone production and male genital development. OBJECTIVES: We aimed to study the associations between levels of amniotic fluid PFOS, fetal steroid hormone, and insulin-like factor 3 (INSL3) and the prevalence of cryptorchidism and hypospadias. METHODS: Using the Danish National Patient Registry, we
Den svenska supply chain-panelen har under 2013 etablerats av forskare från Institutionen för teknisk ekonomi och logistik vid Lunds universitet LTH. Paneldeltagarna svarar på fyra enkla enkäter, kring olika supply chain-frågor. Den andra enkäten, som redovisas här, fokuserade hur företag arbetar med Sales & Operations Planning (S&OP). Analysen bygger på svar från 63 panelmedlemmar från o
Donor-reactive CD4(+) memory T cells threaten the survival of transplanted organs. In this study, we used anti-CD44 monoclonal antibody (mAb) to inhibit adoptively transferred B6-reactive CD4(+) memory T cells (BALB/c origin) and to induce tolerance of B6 hearts in nude mice. The median survival time (MST) of the grafts was 6 days in the isotype group, and more than 100 days in the group treated w
A new simulation method for nonuniform polymer solutions between planar surfaces at full chemical equilibrium is described. The technique uses a grid of points in a two-dimensional thermodynamic space, labeled by surface area and surface separations. Free energy differences between these points are determined via Bennett's optimized rates method in the canonical ensemble. Subsequently, loci of con
A critical factor in simultaneous saccharification and fermentation (SSF) is the selection of process temperature, which needs to be a compromise between the optimal temperature for enzymatic hydrolysis and that for fermentation. In the present work, isothermal and nonisothermal SSF was experimentally studied using pretreated spruce and arundo materials at a loading of 10% water insoluble solids,
Global climate change stands out from most environmental problems because it will span generations and force us to think in new ways about intergenerational fairness. It involves the delicate problem of complex coordination between countries on a truly global scale. As long as fossil fuels are too cheap, climate change policy will engage all major economies. The costs are high enough to make effic
Although capacity development has been identified as the means to substantially reduce global disaster losses, it is a challenge for external partners to facilitate the development of sustainable capacities for disaster risk reduction in disaster-prone countries. The purpose of this study is to investigate potential gaps between how leading professionals approach such capacity development and guid
We introduce a wide subclass F(X, w) of quasi-plurisubharmonic functions in a compact Kahler manifold, on which the complex Monge-Ampere operator is well defined and the convergence theorem is valid. We also prove that F(X, w) is a convex cone and includes all quasi-plurisubharmonic functions that are in the Cegrell class.
Background: Patient-reported outcome (PRO) instruments are used in all medical disciplines to evaluate patients with different diseases and also to follow results after treatments such as surgery. Currently there is no generally accepted and fully validated PRO instrument for the foot and ankle. Aims: To translate the New Zealand Ankle Questionnaire into a Swedish version, [the Self-Reported Foot
C3 and C5 convertases are central stages of the complement cascade since they converge the different initiation pathways, augment complement activation by an amplification loop and lead to a common terminal pathway resulting in the formation of the membrane attack complex. Several complement inhibitors attenuate convertase formation and/or accelerate dissociation of convertase complexes. Functiona
In the quest for efficiency improvement in heavy duty truck engines, waste heat recovery could play a valuable role. The evaporative cycle is a waste heat recovery technology aimed at improving efficiency and decreasing emissions. A humid air motor (HAM) uses the waste heat from the exhaust of the engine to humidify the inlet air; this humid air, with higher specific heat, reduces NOx emission to
The very first data from MAX-lab in Lund, Sweden on pion photoproduction at threshold energies are presented. The decrease of the total π+ yield in γ+12C, 27Al reactions below 200 MeV as well as the dσ/dΩ cross-section data essentially follow the predictions of an intranuclear-cascade model with an attractive potential for the pion–nucleus interaction. However, View the MathML source, cross-sectio
