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Current cancer treatments are associated with high mortality because anticancer drugs are highly toxic and have numerous side effects. Human α-lactalbumin Made Lethal to Tumour cells (HAMLET) is protein-lipid complex that kills tumor cells and spares healthy differentiated cells. HAMLET interacts with a broad range of cellular targets. Our group has shown that the cell death induced by HAMLET can
Denna uppsats undersöker en radikal och aktivistisk del av funktionshinderrörelsen. Den beskriver hur de gör motstånd, mot vad de gör motstånd och hur de ser på sin rörelse. Uppsatsen är en kvalitativ intervjustudie med fem funkisaktivister och har en motstånds- och cripteoretisk ansats. Intervjupersonerna riktar kritik mot stora delar av funktionshinderrörelsen som de menar är för individfokusera
Efficient use of energy becomes increasingly important in the modern society, with climate change as a driving factor. Short term production planning for district heating networks is motivated by a customer demand that varies according to a daily cycle, but which is directly dependent on changes in temperature and customer behaviour. The planning involves challenges in modeling of production unit
This report investigates why more people are killed in house fires in Finland than in Sweden. The report is divided into five different steps, which are comparison of building regulations for fire protection, statistics for fatal fires in both Finland and Sweden, identification of risk factors in fatal fires, existence and development for each identified risk factor in both Finland and Sweden. The
When designing and implementing a prototype supporting inter-destination media synchronization – synchronized playback between multiple devices receiving the same stream – there are a lot of aspects that need to be considered, especially when working with unmanaged networks. Not only is a proper streaming protocol essential, but also a way to obtain and maintain the synchronization of the clocks o
In the years prior to what became known as the Arab Spring, regional public opinion strongly favored Hezbollah due to its principled commitment to the liberation of Palestine. As popular upheavals swept through the Arab Middle East in 2011, this sentiment continued as the movement gave its support to the initial uprisings. However, as the protests reached Syria the image of Hezbollah as a champion
Direct Fastening tools are popular for quick fastenings in concrete and steel by propelling the nail with gun powder, gas or electricity. Because of this the users hand needs to absorb a shock caused by the recoil when a setting is performed. The link between the recoil and its effect on the user is essentially unexplored. This makes it hard to design an optimum handle for a direct fastening tool
The following study aims to examine the structuring functions of migration in relation to globalization, and how these affect the subject. Through interviewing six persons with the experience of migration and living without documents in Malmö, I have analysed the interviewees’ narratives in relation to a global context. This is a qualitative study produced through a narrative method, with the inte
De senaste åren har sjukskrivningarna ökat i Sverige, enligt SCB (2015), vilket påverkar både individ och organisation negativt. Samtidigt råder en träningstrend där träning och kost prioriteras av allt fler i vardagen för att förbättra eller bibehålla sin hälsa. Eftersom sjukfrånvaro är ett samhällsproblem och träning anses generera flera positiva effekter, finner vi det intressant att undersöka
This thesis investigates the media discourse of the Swedish party Feminist Initiative in conjunction with the election to the European Parliament, and the general national election, in May and September 2014. Through the methods of narrative analysis and critical discourse analysis, it identifies the dominating media approaches and attitudes towards the party, and analyses what norms and structure
Integrated reporting is an approach to corporate reporting that seeks to integrate significant financial and non-financial information and demonstrate how they are connected to each other. By doing so, integrated reporting is expected to lead to integrated thinking and decision-making, reflecting how an organisation impacts and is impacted by the economic, social and environmental context in which
Om inte statusen på Sveriges byggnadsbestånd förbättras kommer miljömålet ”God bebyggd miljö” inte kunna uppfyllas. Då miljömålet beaktar många aspekter måste ett holistiskt synsätt gälla vid genomförandet av åtgärder i byggnadsbeståndet. För att kunna göra detta måste en dialog föras kring viktiga aspekter på byggnadens samtliga områden mellan inblandade parter. Om en parameter ändras riskerar de
Thymidine kinase 1 from tomato (ToTK1) is a newly discovered deoxyribonucleoside kinase (dNK) that has been subject to study due to its in vitro and in vivo properties making it an interesting suicide gene candidate for the treatment of brain tumors. The ToTK1 phosphorylates the nucleoside analogue 3-azido-2,3-dideoxythymidine (azidothymidine, AZT) equally well as its natural substrate thymidine (
This study investigates the impact of the Network Code on Capacity Allocation (CACM) on the merchant approach to interconnector development. It also situates CACM in the context of the EU, analysing the progress it makes towards a functioning single market for electricity across European Member States. Known as the Internal Energy Market (IEM), the EU has worked to achieve a single market for over
I denna uppsats undersöks hur klarspråksarbetet organiseras på en mindre svensk kommun utan anställda språkvetare, i termer av institutionella ramar och lokala villkor. Syftet är också att undersöka hur man refererar till klarspråk när man tar fram ett myndighetsdokument, i detta fall en äldreomsorgsplan. Undersökningen är en kvalitativ fallstudie med en kommuni-kationsetnografisk ansats, där fält
India continuously receives a significant number of refugees from neighbouring countries and non. Lacking a proper framework for protection, the government assigned the mandate to UNHCR, thus putting in place a system with the same purpose. Yet, hierarchisation of Indian society on the basis of fixed gender roles, and other institutions in place create conditions of structural violence, particular
Within last four decades, smoking has become a major problem for the Chinese People’s Republic (hereafter: China) as there are annually approximately 1.2 million smoke-related deaths. There are several bans by the national and local governments that have been introduced during the last decade (in years 2008, 2011 and 2014) and bans thus can be said to have a certain tradition. The purpose of the t
Julia Arvidson Hållbarhetsredovisning – Ett verktyg för förbättrat hållbarhetsarbete? Hållbarhetsredovisning har på kort tid vuxit fram som en självklar komponent i ett sunt och hållbart företagande. Nya EU-direktiv ställer krav på fler företag att redovisa för sin verksamhets ekonomiska, miljömässiga och sociala påverkan. Då antalet redovisande företag kommer att öka både i Sverige och i EuropSustainability reporting has emerged as a common practice of 21st-century business. A sustainability report is a report published by an organization that presents the economic, environmental and social impacts caused by its activities. The Global Reporting Initiative (GRI) is a non-profit organization with the mission to promote the transition to a sustainable global economy by providing a framewo
