Parkinson's disease (PD) is a complex neurodegenerative disorder in which both rare and common genetic variants contribute to disease risk. Multiple genes have been reported to be linked to monogenic PD but these only explain a fraction of the observed familial aggregation. Rare variants in RIC3 have been suggested to be associated with PD in the Indian population. However, replication studies yie

The present article is situated in an unexplored embodied geography with re-lation to Gender Studies and Alternative Feminist Pedagogies: the department of Santander in Colombia, located in the north eastern part of the country. It presents the results of empirical application of the autobiographical method created with the aim of considering possibilities to decolonize learning pro-cesses in univ

The reflections compiled in this chapter emerge from the two fieldwork investigations conducted in Brazil (2016) and Colombia (2015). The first one, carried out in the favelas of Rio de Janeiro, aims to understand and analyse the nature and the impacts of police violence, as well as resistance emerging in that context, based on women’s testimonies. The second one has been implemented with the coll

Bacterial endotoxin is a potent inflammatory antigen abundant in the human intestine. Endotoxins circulate in the blood at low concentrations in all healthy individuals. Elevated levels of circulatory endotoxins may cause inflammation with the development of chronic disease, either affecting metabolism, neurological disease, or resistance to viral and bacterial infections. The most important endot

Stories are being increasingly recognised for their potential as creators, not only depicters, of change. As such, they are receiving greater interest within sustainability science, not least in the approaches specifically focused on transformative processes of co-creation. But while highly powerful, stories are confined by both inherent and external frameworks that, if not acknowledged, limit the

Aim: Macroecological analyses provide valuable insights into factors that influence how parasites are distributed across space and among hosts. Amid large uncertainties that arise when generalizing from local and regional findings, hierarchical approaches applied to global datasets are required to determine whether drivers of parasite infection patterns vary across scales. We assessed global patte

Insect migration redistributes enormous quantities of biomass, nutrients and species globally. A subset of insect migrants perform extreme long-distance journeys, requiring specialized morphological, physiological and behavioral adaptations. The migratory globe skimmer dragonfly (Pantala flavescens) is hypothesized to migrate from India across the Indian Ocean to East Africa in the autumn, with a

Purpose: Endwall film cooling protects vane endwall by coolant coverage, especially at the leading edge (LE) region and vane-pressure side (PS) junction region. Strong flow impingement and complex vortexaa structures on the vane endwall cause difficulties for coolant flows to cover properly. This work aims at a full-scale arrangement of film cooling holes on the endwall which improves coolant effi

Background: Functional head impulse test (fHIT) tests the ability of the vestibulo-ocular reflex (VOR) to allow visual perception during head movements. Our previous study showed that active head movements to the side with a vestibular lesion generated a dynamic visual performance that were as good as during movements to the intact side. Objective: To examine the differences in eye position during

Grundskolan i Sverige har sedan 1962 haft den form den har idag och innehållet har styrts av läroplaner och kursplaner. De har förnyats och omformulerats under åren och Sverige har hittills haft fem olika läroplaner. I denna uppsats har jag undersökt diskursen gällande kön och genus med fokus på musikämnet i läroplaner och kursplaner. Jag har även undersökt en del kringmaterial. Jag har gjort en k

This practice-based PhD project investigates the conditions for a pedagogy of the utopian image in contemporary art and film. It starts from the premise that there is a need for new political and social visions and scenarios. The project asks what role art and artist film, both as a medium and as a social activity, can play in experimenting with and sketching such visions and scenarios – a process

Background and aims: Neurotensin (NT) is an intestinal peptide released after fat ingestion, which regulates appetite and facilitates lipid absorption. Elevated plasma levels of its stable precursor pro-neurotensin (pro-NT) are associated with type 2 diabetes, obesity and cardiovascular mortality in adult populations; no data on pro-NT and metabolic disease are available in children. Aim of the st

This article provides a rationale for inner transformation as a key and hitherto underresearched dimension of sustainability transformations. Inner transformation relates to various aspects of human existence and interactions such as consciousness, mindsets, values, worldviews, beliefs, spirituality and human–nature connectedness. The article draws on Meadows’ leverage points approach, as places t

Background: Totally implantable venous access devices (TIVADs) have improved the quality of life for seriously ill and cancer patients. These devices represent a convenient option when long-term venous access is indicated. The Subclavian and Internal Jugular Veins are the vessels of choice for catheterization [1]. However, if it is not possible to catheterize them, an alternative vein should be so

Introduction and aim: Air pollution, a major environmental threat to human health, contributes to the premature deaths of millions of people worldwide. Cooking with solid fuels, such as charcoal and wood, in low-and middle-income countries generates very high emissions of particulate matter within and near the household as a result of their inefficient combustion. Women are especially exposed, as

We systematically investigate the complexity of counting subgraph patterns modulo fixed integers. For example, it is known that the parity of the number of k-matchings can be determined in polynomial time by a simple reduction to the determinant. We generalize this to an nf(t,s)-time algorithm to compute modulo 2t the number of subgraph occurrences of patterns that are s vertices away from being m