Gene-lifestyle interactions have been suggested to contribute to the development of type 2 diabetes. Glucose levels 2 h after a standard 75-g glucose challenge are used to diagnose diabetes and are associated with both genetic and lifestyle factors. However, whether these factors interact to determine 2-h glucose levels is unknown. We meta-analyzed single nucleotide polymorphism (SNP) X BMI and SN

A highly selective, interference free biosensor for the measurement of fructose in real syrup samples was developed. The assay is based on the phosphorylation of D(-)fructose to fructose-6-phosphate by hexokinase and subsequent conversion of fructose-6-phosphate to fructose-1,6-biphosphate by fructose-6-phosphate-kinase. The heat liberated in the second reaction is monitored using an enzyme thermi

The PHENIX experiment has measured the production of pi(0)s in Au + Au collisions at root S-NN = 200 GeV. The new data offer a fourfold increase in recorded luminosity, providing higher precision and a larger reach in transverse momentum, p(T), to 20 GeV/c. The production ratio of eta/pi(0) is 0.46 +/- 0.01(stat) +/- 0.05(syst), constant with p(T) and collision centrality. The observed ratio is co

The distribution and orientation of energy inside jets is predicted to be an experimental handle on colour connections between the hard-scatter quarks and gluons initiating the jets. This Letter presents a measurement of the distribution of one such variable, the jet pull angle. The pull angle is measured for jets produced in t (t) over bar events with one W boson decaying leptonically and the oth

Genetic markers can be used as instrumental variables, in an analogous way to randomization in a clinical trial, to estimate the causal relationship between a phenotype and an outcome variable. Our purpose is to extend the existing methods for such Mendelian randomization studies to the context of multiple genetic markers measured in multiple studies, based on the analysis of individual participan

Context. The solution of the nonlocal thermodynamical equilibrium (non-LTE) radiative transfer equation usually relies on stationary iterative methods, which may falsely converge in some cases. Furthermore, these methods are often unable to handle large-scale systems, such as molecular spectra emerging from, for example, cool stellar atmospheres. Aims. Our objective is to develop a new method, whi

Popular Abstract in SwedishBarn till föräldrar med psykisk ohälsa är en eftersatt grupp. Syftet med denna studie är att studera pedagogers utveckling som kompletterande anknytningsperson i relation till en tre-årig fortbildning.Fortbildnigen ägde rum samtidigt som pedagogerna arbetade och innehöll teorier om barns utveckling, nämligen anknytningsteori, affektteori samt Sterns teori om barns självuChildren whose parents suffer from mental illness are a neglected group. The child´s need of a secure predictable grown up, is not always compatible with the parents abilities to care for the child. The objective in the thesis is to study and analyse preschool teacher´s development in relation to an in-service training for a period of three years and to study the development of the teacher´s work

Background: Propionibacterium acnes is a commensal of human skin but is also known to be involved in certain diseases, such as acne vulgaris and infections of orthopaedic implants. Treatment of these conditions is complicated by increased resistance to antibiotics and/or biofilm formation of P. acnes bacteria. P. acnes can be infected by bacteriophages, but until recently little has been known abo

We propose a new model that accounts for the asymmetric response of volatility to positive (`good news') and negative (`bad news') shocks in economic time series – the so-called leverage effect. In the past, asymmetric powers of errors in the conditionally heteroskedastic models have been used to capture this effect. Our model is using the gamma difference representation of the generalized Laplace

This Letter presents a search at the LHC for s-channel single top-quark production in proton-proton collisions at a centre-of-mass energy of 8 TeV. The analyzed data set was recorded by the ATLAS detector and corresponds to an integrated luminosity of 20.3 fb(-1). Selected events contain one charged lepton, large missing transverse momentum and exactly two b-tagged jets. A multivariate event class

Objective. The goal with this study was to evaluate the analytical performance of a new cystatin C immunoassay (Tina-quant (R) a Cystatin C, Roche Diagnostics GmbH). The evaluation was carried out at four centers according to a standardized protocol. Material and methods. The Tina-quant (R) a Cystatin C is a latex particle-enhanced immunoturbidimetric assay. Roche cobas (R) 6000, MODULAR ANALYTICS

The evolution of the nuclear shell structure in the region of the neutron-rich shell-breaking nucleus Mg-32 has been the subject of considerable interest. We present here the first determination of the overlap of the ground and two first excited states in Mg-31 with a neutron coupled to the ground state in Mg-30 based on studies of its isobaric analog resonances in Al-31. The excitation function f