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Novel metric “Implenarity” for characterization of shape and defectiveness : The case of CFRP hole quality

Image Processing is rapidly expanding as a technique for object and defect analysis because of the high ease of its coupling to automation and IT solutions. Yet, issues with transferability of the measurement approaches and metrics currently used in mechanical systems often remain unsolved. Study reports on the developed approach for shape and defectiveness characterization by combining Delaunay t

Software development and innovation : Exploring the software shift in innovation in Swedish firms

A number of scholars and industry professionals have claimed that there has been a ‘software-biased shift’ in the nature and direction of innovation, in that software development is a core part of innovation activities in firms across a wide array of industries. Empirical firm-level evidence of such a shift is still scant. In this paper, we employ new and unique firm-level survey data on the frequ

Simulation of the response of the Solid State Neutron Detector for the European Spallation Source

The characteristics of the Solid-state Neutron Detector, under development for neutron-scattering measurements at the European Spallation Source, have been simulated with a Geant4-based computer code. The code models the interactions of thermal neutrons and ionising radiation in the 6Li-doped scintillating glass of the detector, the production of scintillation light and the transport of optical, s

High-resolution assessment of environmental benefits of dockless bike-sharing systems based on transaction data

Dockless bike-sharing systems (DLBS) have gained much popularity due to their environmentally friendly features. This study puts forward a distinctive framework for assessing the environmental influences of DLBS in high resolution based on DLBS transaction data. The proposed framework firstly estimates the transport mode substituted by DLBS for each recorded bike-sharing trip by utilizing the rout

Meta-analysis of prospective studies evaluating breast cancer detection and interval cancer rates for digital breast tomosynthesis versus mammography population screening

Introduction: Breast cancer (BC) screening using digital breast tomosynthesis (DBT) has been shown to increase cancer detection compared with mammography; however, it is unknown whether DBT impacts interval cancer rate (ICR). Methods: We systematically identified prospective DBT studies reporting data on screen-detected and interval BCs to perform a study-level meta-analysis of the comparative eff

Orientational Ambiguity in Septin Coiled Coils and its Structural Basis

Septins are an example of subtle molecular recognition whereby different paralogues must correctly assemble into functional filaments important for essential cellular events such as cytokinesis. Most possess C-terminal domains capable of forming coiled coils which are believed to be involved in filament formation and bundling. Here, we report an integrated structural approach which aims to unravel

An enhanced multi-fiber reconstruction technique using adaptive gradient directions coupled with MoNCW model in diffusion MRI

In this paper, we introduced a novel approach for generating unit gradient vectors named as adaptive gradient directions (AGD) for reconstructing single and decussating (crossing or kissing) white matter fibers in brain. The present study is focusing on reconstruction process of brain's white matter fibers but not dealing with data acquisition where scanning is performed. The gradient vectors used

Predictors of mortality in patients with different apolipoprotein E genotypes—a 20-year follow-up of Alzheimer’s disease.

Background: To identify apolipoprotein E (APOE)-specific factors that may predict life expectancy after a diagnosis of Alzheimer’s disease (AD). Method: The Swedish Alzheimer Treatment Study (SATS) is a prospective, observational, clinical-practice-based, multicentre study that includes 999 participants diagnosed with mild-to-moderate AD at the start of cholinesterase inhibitor (ChEI) therapy (tim

Waist circumference and a body shape index and prostate cancer risk and mortality

We recently found a negative association between body mass index (BMI) and the risk of localised prostate cancer (PCa), no association with advanced PCa, and a positive association with PCa‐specific mortality. In a 15% subpopulation of that study, we here investigated the measures of abdominal adiposity including waist circumference (WC) and A Body Shape Index (ABSI) in relation to PCa risk and mo

Vocational Outcomes of the Individual Placement and Support Model in Subgroups of Diagnoses, Substance Abuse, and Forensic Conditions : A Systematic Review and Analysis of Pooled Original Data

Purpose: To investigate the effect of Individual Placement and Support (IPS) according to diagnoses of schizophrenia, bipolar disorder, major depression, substance use disorders, or forensic psychiatric conditions. Methods: A systematic search of the literature was conducted in June 2017 and repeated in December 2020. The systematic review included 13 studies. Analyses of pooled original data were

Putting Trust into Antitrust? Competition Policy and Data-Driven Platforms

Anti-competitive notions, it seems, are increasingly informing the critical debate on a data-driven economy organised into scalable digital platforms. Issues of market definitions, how to value personal data on multisided platforms, and how to detect and regulate misuses of dominant positions have become key nomenclature on the battlefield of addressing fairness in our contemporary digital societi

Towards system oriented innovation policy evaluation? Evidence from EU28 member states

Many years after the introduction of the innovation system concept in innovation policy design, it is still not clear whether innovation policy evaluation practices follow a system approach. Building on evaluation and innovation studies, this article develops the concept 'system oriented innovation policy evaluation’ based on four attributes (coverage, perspective, temporality and expertise). The

In-Motion-App for remote General Movement Assessment : A multi-site observational study

Objectives To determine whether videos taken by parents of their infants' spontaneous movements were in accordance with required standards in the In-Motion-App, and whether the videos could be remotely scored by a trained General Movement Assessment (GMA) observer. Additionally, to assess the feasibility of using home-based video recordings for automated tracking of spontaneous movements, and to e

The prognostic impact of the tumour stroma fraction : A machine learning-based analysis in 16 human solid tumour types

Background: The development of a reactive tumour stroma is a hallmark of tumour progression and pronounced tumour stroma is generally considered to be associated with clinical aggressiveness. The variability between tumour types regarding stroma fraction, and its prognosis associations, have not been systematically analysed. Methods: Using an objective machine-learning method we quantified the tum

Valuable aspects of home rehabilitation in Sweden : Experiences from older adults

Background and aim: Home rehabilitation is an increasing service in many countries due to the aging population. The body of knowledge in home rehabilitation is growing but results are inconsistent, and there is still lack of knowledge from user perspectives to guide practice and home rehabilitation programs. The purpose of this study was to explore valuable aspects of home rehabilitation experienc