The aim of this study was to translate and adapt the Sydney Swallow Questionnaire to Swedish conditions and to evaluate the validity and test-retest reliability of the Swedish translation in patients with oropharyngeal dysphagia and in healthy controls.

We performed a genome-wide association study on 1,292 individuals with abdominal aortic aneurysms (AAAs) and 30,503 controls from Iceland and The Netherlands, with a follow-up of top markers in up to 3,267 individuals with AAAs and 7,451 controls. The A allele of rs7025486 on 9q33 was found to associate with AAA, with an odds ratio (OR) of 1.21 and P = 4.6 x 10(-10). In tests for association with

We verified an active uptake of kleptoplastids in the toxic and bloom-forming dinoflagellates of the genus Dinophysis from its preferred prey, the ciliate Myrionecta rubra, using a quantitative real-time PCR technique. During a 65 d starvation/feeding experiment with Dinophysis caudata, changes in plastid 16S rRNA, plastid autofluorescence and plastid/nuclear DNA ratio through the cell cycle were

Objectives: To perform a genome-wide association study (GWAS) using the Immunochip array in 3,420 cases of ischemic stroke and 6,821 controls, followed by a meta-analysis with data from more than 14,000 additional ischemic stroke cases. Methods: Using the Immunochip, we genotyped 3,420 ischemic stroke cases and 6,821 controls. After imputation we meta-analyzed the results with imputed GWAS data fr

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Intervju: "När vi andra ser gungor, rutschbanor och berg- och dalbanor ser Ann-Marie Pendrill mängder av tillfällen att uppleva, prata om och räkna med fysik. – Fysik är ett lekfullt ämne."

Expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate with favourable clinicopathological parameters and prognosis in several cancer diseases. The aim of this study was to examine the expression and prognostic ability of RBM3 in patients with testicular non-seminomatous germ cell tumours (NSGCT).

The present Comite´ Europe´en de Normalisation (CEN) and International Organization for Standardization (ISO) standards for safety, protective and occupational footwear EN ISO 20344–20347 classify footwear as cold protective by a pass/fail test where the limits are set for an allowed 10 °C temperature drop inside the footwear during 30 min at a temperature gradient of ~40 °C. It is questionable if

To obtain insights into the coupling between community composition, diversity and community function, bacterioplankton assemblages from the Gulf of Trieste (Northern Adriatic Sea) were exposed to increasing environmental stress throughout 2 wk in continuous seawater cultures to construct communities differing in composition and diversity. The assemblages were exposed to (1) decreased temperature,

The life-history parameters of most living organisms are modified by fluctuations in environmental conditions. The impact of environmental autocorrelation on population persistence is well understood in single species systems. However, in multi-species communities the impact of stochasticity is complicated by the possibility of different species having differing intrinsic responses to the environm

To explore interactions between climate and peatland hydrology, Scots pine (Pinus sylvestris L.) growing at four raised bogs in southern Sweden were subject to a dendroclimatological study. Radial tree growth reflecting climate and water table fluctuations over multiannual periods was detected as significant negative correlations between tree-ring width (TRW) chronologies and the preceding one to

The neurobiological basis and temporal dynamics of communicative language processing pose important yet unresolved questions. It has previously been suggested that comprehension of the communicative function of an utterance, i.e. the so-called speech act, is supported by an ensemble of neural networks, comprising lexico-semantic, action and mirror neuron as well as theory of mind circuits, all act

Zoophilous flowers often transmit olfactory signals to attract pollinators. In plants with unisexual flowers, such signals are usually similar between the sexes because attraction of the same animal to both male and female flowers is essential for conspecific pollen transfer. Here, we present a remarkable example of sexual dimorphism in floral signal observed in reproductively highly specialized c

Effects of land use changes are starting to be included in estimates of life-cycle greenhouse gas (GHG) emissions, so-called carbon footprints (CFs), from food production. Their omission can lead to serious underestimates, particularly for meat. Here we estimate emissions from the conversion of forest to pasture in the Legal Amazon Region (LAR) of Brazil and present a model to distribute the emiss

Popular Abstract in Swedish De senaste årtiondena har det diskuteras om det finns anledning till oro när det gäller mannens reproduktionsfunktion. Vissa forskningsresultat tyder på att spermieantalet har minskat och fler män har diagnostiserats med testikelcancer och medfödda missbildningar av könsorganen än tidigare. Om detta beror på genetiska faktorer, livsstil eller miljöfaktorer, eller alla tAndrogens regulate male reproductive function and their effects are mediated through the androgen receptor (AR). The AR gene contains a polymorphic CAG repeat, encoding a stretch of glutamines, affecting the transcriptional activity of the AR. Prostate specific antigen (PSA) is a downstream target and is commonly used in the screening of prostate cancer. The relationship between CAG number and mal

The degradation of live plant biomass in fungus gardens of leaf-cutting ants is poorly characterised but fundamental for understanding the mutual advantages and efficiency of this obligate nutritional symbiosis. Controversies about the extent to which the garden-symbiont Leucocoprinus gongylophorus degrades cellulose have hampered our understanding of the selection forces that induced large scale