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The effect to knock on the heat transfer in a spark-ignition engines : Cars temperature measurements in the thermal boundary layer combined with heat-flux measurements

The temperature in the thermal boundary layer close to the combustion chamber wall was measured under knocking and non-knocking conditions using dual-broadband rotational coherent anti-Stokes Raman Scattering (CARS). A horseshoe-shaped combustion extension was employed to get an optical access to the region near the combustion chamber wall. Time-resolved measurements of the cylinder pressure (at t

Spatially Distributed Hydrological Modelling : Wetness Derived from Digital Elevation Models to Estimate Peatland Carbon

To study the hydrology of peatlands and explore wetness distribution is difficultmainly due to the complexity of the surface of peatlands, and also due to the presence of permafrost underlain peatlands in the arctic regions. I have chosen the area called Stordalen mire in the arctic region in northern Sweden for my study.In this thesis, I aimed to study spatially distributed hydrological modelling

Fourfold higher tundra volatile emissions due to arctic summer warming

Biogenic volatile organic compounds (BVOCs), which are mainly emitted by vegetation, may create either positive or negative climate forcing feedbacks. In the Subarctic, BVOC emissions are highly responsive to temperature, but the effects of climatic warming on BVOC emissions have not been assessed in more extreme arctic ecosystems. The Arctic undergoes rapid climate change, with air temperatures i

Climate sensitivity of shrub growth across the tundra biome

Rapid climate warming in the tundra biome has been linked to increasing shrub dominance. Shrub expansion can modify climate by altering surface albedo, energy and water balance, and permafrost, yet the drivers of shrub growth remain poorly understood. Dendroecological data consisting of multi-decadal time series of annual shrub growth provide an underused resource to explore climate-growth relatio

Treatment with a GnRH receptor agonist, but not the GnRH receptor antagonist degarelix, induces atherosclerotic plaque instability in ApoE-/- mice

Androgen-deprivation therapy (ADT) for prostate cancer has been associated with increased risk for development of cardiovascular events and recent pooled analyses of randomized intervention trials suggest that this primarily is the case for patients with pre-existing cardiovascular disease treated with gonadotropin-releasing hormone receptor (GnRH-R) agonists. In the present study we investigated

Fighting Off Wound Pathogens in Horses with Honeybee Lactic Acid Bacteria

In the global perspective of antibiotic resistance, it is urgent to find potent topical antibiotics for the use in human and animal infection. Healing of equine wounds, particularly in the limbs, is difficult due to hydrostatic factors and exposure to environmental contaminants, which can lead to heavy bio-burden/biofilm formation and sometimes to infection. Therefore, antibiotics are often prescr

Chemical penetration enhancers in stratum corneum - Relation between molecular effects and barrier function

Skin is attractive for drug therapy because it offers an easily accessible route without first-pass metabolism. Transdermal drug delivery is also associated with high patient compliance and through the site of application, the drug delivery can be locally directed. However, to succeed with transdermal drug delivery it is often required to overcome the low permeability of the upper layer of the ski

Reliability, validity and clinical correlates of the Quality of Life in Alzheimer's disease (QoL-AD) scale in medical inpatients

Background: There is a lack of standardisation in quality of life (QoL) measurements to be used in older multimorbid patients. An ideal QoL measurement should be reliable, valid, subjective, multidimensional, feasible and generic. We hypothesised that the QoL-AD (Quality of Life in Alzheimer's Disease) scale could have these properties. Our aim was to determine the psychometric properties and clin

Moonlighting of Helicobacter pylori catalase protects against complement-mediated killing by utilising the host molecule vitronectin

Helicobacter pylori is an important human pathogen and a common cause of peptic ulcers and gastric cancer. Despite H. pylori provoking strong innate and adaptive immune responses, the bacterium is able to successfully establish long-term infections. Vitronectin (Vn), a component of both the extracellular matrix and plasma, is involved in many physiological processes, including regulation of the co