This chapter deals with the need to intentionally support staff in developing evidence-based skills. While formal teaching has a place, most activity will be mentor based. We present a suggested minimum skill set and discuss ways of maintaining developments.

We report on a study of the room-temperature nonlinear charge transport properties of three-terminal junction devices made from graphene. We demonstrate that the graphene three terminal junction devices show a rectification characteristic, namely, when voltages V-L V and V-R -V are applied to the left and the right terminal in a push-pull configuration, the voltage output from the central terminal

Emerging knowledge of the role of atheroprotective immune responses in modulating inflammation and tissue repair in atherosclerotic lesions has provided promising opportunities to develop novel therapies directly targeting the disease process in the artery wall. Regulatory T (Treg) cells have a protective role through release of anti-inflammatory cytokines and suppression of auto-reactive effector

BACKGROUND: Although several studies have investigated the association of the Mediterranean diet with overall mortality or risk of specific cancers, data on overall cancer risk are sparse. METHODS: We examined the association between adherence to Mediterranean dietary pattern and overall cancer risk using data from the European Prospective Investigation Into Cancer and nutrition, a multi-centre pr

Introduction The intensity and duration of childhood cancer treatment may disrupt psychosocial development and thereby cause difficulties in transition into adulthood. The study objective was to assess social outcomes in early adulthood after successful treatment for childhood acute myeloid leukemia (AML), Wilms tumor (WT) and infratentorial astrocytoma (IA). Methods Nordic patients treated for AM

Heat transfer and pressure drop characteristics of a hybrid nanofluid mixture containing alumina nanoparticles and multi-walled carbon nanotubes (MWCNTs) were experimentally investigated in a chevron corrugated-plate heat exchanger. A MWCNT/water nanofluid with a volume concentration of 0.0111% and an Al2O3/water nanofluid with a volume concentration of 1.89% were mixed at a volume ratio of 1:2.5.

A search is presented for pair production of a new heavy quark (Q) that decays into aW boson and a light quark (q) in the final state where one W boson decays leptonically (to an electron or muon plus a neutrino) and the other W boson decays hadronically. The analysis is performed using an integrated luminosity of 20.3 fb(-1) of pp collisions at root s = 8 TeV collected by the ATLAS detector at th

Aims Biogeographical evidence suggests a strong link between climate and patterns of species diversity, and climate change is known to cause range shifts. However, there is little understanding of how shifts affect community composition and we lack empirical evidence of recent impacts of climate change on the diversity of vertebrates. Using a long-term comprehensive dataset on bird abundance, we e

Rate control of atrial fibrillation (AF) is a main treatment modality. However, data are scarce on the relative efficacy of calcium channel blockers and 13 blockers or between drugs within each class. The purpose of the present study was to compare the effect of 4 rate-reducing, once-daily drug regimens on the ventricular heart rate and arrhythmia-related symptoms in patients with permanent AF. We

This study develops a term structure model for VIX futures. Instead of deriving the VIX futures price from a model for the instantaneous variance of the S&P 500 or a model for the VIX, the VIX futures price dynamics are specified exogenously. The empirical features of VIX futures returns (positive skewness, excess kurtosis, and a decreasing volatility term structure for longer term expirations

The psychometric properties of the Child PTSD Symptom Scale (CPSS) were examined in 2 samples. Sample 1 (N 185, ages 6–17 years) consisted of children recruited from hospitals after accidental injury, assault, and road traffic trauma, and assessed 6 months posttrauma. Sample 2 (N 68, ages 6–17 years) comprised treatment-seeking children who had experienced diverse traumas. In both samples psychome

Although flying insects have limited visual acuity (approx. 1°) and relatively small brains, many species pursue tiny targets against cluttered backgrounds with high success. Our previous computational model, inspired by electrophysiological recordings from insect 'small target motion detector' (STMD) neurons, did not account for several key properties described from the biological system. These i

To investigate whether preoperative retinal function measured by full-field ERG and multifocal ERG is correlated to postoperative visual acuity after macular hole surgery.

Benchmarking is becoming a more and more commonly used method for quality assurance and enhancement in higher education today. The aim of this study was to explore the impact and value of benchmarking e-learning in universities. Two European benchmarking initiatives, E-xcellence+ through the European Association of Distance Teaching Universities [EADTU] and an e-learning benchmarking exercise thro

Background: Self-injury, a manifestation of severe psychological distress, is increased in cancer-bereaved youths. Little is known about the potential influence on the risk for self-injury of factors that could be clinically relevant to and modifiable by the health-care professionals involved in the care of the dying parent. Methods: In a nationwide population-based anonymous study, 622 (73.1%) yo

The preservative methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is a well-known sensitiser and present in most baseline series since at least 20 years. The proportions of MCI/MI are 3:1. MI alone has been used as a preservative in occupational and household products, and cosmetics since less than 10 years. MCI/MI tested at 100 ppm fails to detect a significant percentage of contact-all

The New Zealand emissions trading scheme (NZ ETS) is one of the first national-level GHG trading schemes outside Europe. It is also unique in its design and comprehensive sectoral coverage, including forestry. This paper provides an ex-post-assessment of market behavior in the NZ ETS in its first phase (2008-2012). Findings are based on quantitative evidence on prices and units, as well as qualita

Objective: Compare the impact of two interventions, a web-based support and a folder support, for young persons who care for people who suffer from mental illness. Methods: This study was a randomized control trial, following the CONSORT statements, which compared the impact of two interventions. Primary outcome variable was stress, and secondary outcome variables were caring situation, general se

We introduce a new solution concept to problems with externalities, which is the first in the literature to take into account economic, regulatory and physical stability aspects of network problems in the very same model. A new class of cooperative games is defined where the worth of a coalition depends on the behavior of other players and on the state of nature as well. We allow for coalitions to