This article explores how policy-makers are managing scientific uncertainty in policy-making. This is done through a case study of the Swedish climate change policy process from 1975 to 2007, based on interviews and an extensive review of official publications and documents. The study shows that scientific uncertainty played a very marginal role in the development of Swedish climate politics. When

Satisfaction with the outcome of treatment is a widely used outcome measure but information about the determinants of patient satisfaction after surgery for central spinal stenosis (CSS) are lacking. The aim of the study was to analyze determinants of patient satisfaction 1 year after surgery for CSS without degenerative spondylolisthesis (DS).

In adults, the size of the left atria (LA) has important prognostic information. In obese adults, adolescents and children enlargement of LA have been observed. This has not been investigated on a population-based level in young children. We therefore assessed if total body fat mass (TBF), abdominal fat, and body fat distribution were related to LA diameter. Cross-sectional study of 244 children (

This paper uses a modified dictator game to investigate the relationship between response times and social preferences. We find that faster subjects more often chose the option with the highest payoff for themselves. Moreover, our within-analysis reveals that, for a given individual, payoff maximizing choices are reached quicker than choices expressing social preferences

Information about genetic variation has been collected for some 20 years into registries, known as locus specific databases (LSDBs), which nowadays often contain information in addition to the actual genetic variation. Several issues have to be taken into account when considering establishing and maintaining LSDBs and these have been discussed previously in a number of articles describing guidelin

Psychosocial stress in adulthood is associated with a higher risk of type 2 diabetes, possibly mediated by behavioural and physiological factors. However, it is unknown whether low stress resilience earlier in life is related to subsequent development of type 2 diabetes. We examined whether low stress resilience in late adolescence is associated with an increased risk of type 2 diabetes in adultho

TCF7L2 harbors the variant with the strongest effect on type 2 diabetes (T2D) identified to date, yet the molecular mechanism as to how variation in the gene increases the risk for developing T2D remains elusive. The phenotypic changes associated with the risk genotype suggest that T2D arises as a consequence of reduced islet mass and/or impaired function, and it has become clear that TCF7L2 plays

Post-operative renal dysfunction after cardiac surgery is not uncommon and can lead to adverse outcome. The ability to accurately monitor renal function is therefore important. Cystatin C is known to be a sensitive marker of the glomerular filtration rate (GFR), but it has not been fully evaluated in cardiac surgery. Iohexol clearance is considered a reliable reference method for the determination

The applicability of manufacturing planning and control methods differs between environments. This paper explains the fit between the planning environment and material and capacity planning on the detailed material planning and shop floor control levels. The study is based on a conceptual discussion and a survey of 84 Swedish manufacturing companies. Results show the use of planning methods and th

The present investigation describes some mental causal models used in incident reports. Some of the models (e.g., single-cause models) are simpler than others (e.g., causal-tree models). The models are also associated with different ways of explaining an incident or accident and with different recommendations for increasing the safety of a system. In study 1, incident reports from Swedish nuclear

It has long been recognized that arterial inflammation plays a key role in the development of atherosclerosis. More recent evidence has suggested that this inflammation is modulated by autoimmune responses against modified self-antigens, such as oxidized low-density lipoprotein, in the vascular wall. However, the role of the immune system in atherosclerosis appears to be more complex than in class

The first results from the stopped beam RISING experimental campaign performed at the GSI laboratory in Darmstadt, Germany, are presented. RISING (Rare ISotope Investigations at GSI) constitutes a major new experimental program in European nuclear structure physics research aimed at using relativistic energy (typically around 1 GeV per nucleon) projectile fragmentation reactions to populate nuclei

Essä om författarens arbete med att restaurera och rekonstruera G W Pabsts stumfilmsklassiker Den glädjelösa gatan (Die Freudluse Gasse, 1925) och hur det påverkat synen på filmens historia och utveckling av berättartekniken.

Pancreatic islets have a central role in blood glucose homeostasis. In addition to insulin-producing beta-cells and glucagon-secreting alpha-cells, the islets contain somatostatin-releasing delta-cells(1). Somatostatin is a powerful inhibitor of insulin and glucagon secretion(2). It is normally secreted in response to glucose(3) and there is evidence suggesting its release becomes perturbed in dia

The thesis concerns risk and safety in manufacturing companies in a developing country. Risk and safety is viewed as integral to the social relations between management and labour. The Malaysian case presents a historical conjuncture of this conflict theme, which is very different from that of its Western genesis. On this basis, the primary objective of the thesis is defined as an effort to escape

The pheromone-mediated upwind flight of male turnip moths was observed in a flight tunnel at different times of day under conditions of a light-dark (LD) cycle, constant darkness (DD), and a shifted photoperiod. Under both LD and DD conditions, a significantly larger number of males flew to the pheromone during both the scotophase and the subjective scotophase than during the photophase and the su