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Traceable calibration with 177Lu and comparison of activity meters at hospitals in Norway and Sweden

Introduction: The activity meter is used to determine the activity of delivered radiopharmaceuticals, administered activity to patients and reference activity when gamma-cameras are calibrated prior to imaged-based dosimetry. The aim is to describe a procedure for cross-calibration of activity meters at different clinical sites, and report on 177Lu activity results when using factory-set calibrati

Multireference Protonation Energetics of a Dimeric Model of Nitrogenase Iron-Sulfur Clusters

Characterizing the electronic structure of the iron-sulfur clusters in nitrogenase is necessary to understand their role in the nitrogen fixation process. One challenging task is to determine the protonation state of the intermediates in the nitrogen fixing cycle. Here, we use a dimeric iron-sulfur model to study relative energies of protonation at C, S, or Fe. Using a composite method based on co

Multiplicity of grain boundary structures and related energy variations

Ideal minimum-energy grain boundary (GB) structures are usually the only ones considered when characterizing GBs. This limited perspective provides an incomplete view of the possible structural variability of GBs. In the present study, phase field crystal (PFC) simulations are employed in a systematic search of GB states based on -surface sampling, demonstrating PFC to be a capable tool for this p

Different antibiotic treatments for group A streptococcal pharyngitis

Background: Antibiotics provide only modest benefit in treating sore throat, although their effectiveness increases in people with positive throat swabs for group A beta-haemolytic streptococci (GABHS). It is unclear which antibiotic is the best choice if antibiotics are indicated. This is an update of a review first published in 2010, and updated in 2013, 2016, and 2021. Objectives: To assess the

Broken bodies, places and objects : New perspectives on fragmentation in archaeology

Broken Bodies, Places and Objects demonstrates the breadth of fragmentation and fragment use in prehistory and history and provides an up-to-date insight into current archaeological thinking around the topic. A seal broken and shared by two trade parties, dog jaws accompanying the dead in Mesolithic burials, fragments of ancient warships commodified as souvenirs, parts of an ancient dynastic thron

ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition

High-risk neuroblastoma (NB) is a significant clinical challenge. MYCN and Anaplastic Lymphoma Kinase (ALK), which are often involved in high-risk NB, lead to increased replication stress in cancer cells, suggesting therapeutic strategies. We previously identified an ATR (ataxia telangiectasia and Rad3-related)/ALK inhibitor (ATRi/ALKi) combination as such a strategy in two independent genetically

Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the single-cell fecal parasitome in children with celiac disease autoimmunity : a randomized, double-blind placebo-controlled clinical trial

BACKGROUND: Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 positively affect the fecal bacteriome in children with celiac disease autoimmunity after 6 months of supplementation. The aim of the present investigation was to study the effects of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 on the single-cell parasitome, with a primary focus

Proteomic Determinants of Variation in Cholesterol Efflux : Observations from the Dallas Heart Study

High-density lipoproteins (HDLs) are promising targets for predicting and treating atherosclerotic cardiovascular disease (ASCVD), as they mediate removal of excess cholesterol from lipid-laden macrophages that accumulate in the vasculature. This functional property of HDLs, termed cholesterol efflux capacity (CEC), is inversely associated with ASCVD. HDLs are compositionally diverse, associating

Taxonomical lives : The making of social divisions in the Swedish press during the golden age of social democracy, 1945–76

This article investigates the media lives of a particular class taxonomy in the Swedish press from 1945 to 1976. Invented by the Central Bureau of Statistics in 1911, the ‘social group division’ system was abandoned in the early post-war period. Around the same time, however, it gained popularity in Swedish culture and political debate. While earlier research has noted that such bureaucratic class

Interferometric quantum control (IQC) by fs/ns rotational coherent anti-Stokes Raman spectroscopy (RCARS)

A new rotational coherent anti-Stokes Raman spectroscopy (RCARS) concept based on interferometric quantum control (IQC) is demonstrated. Two wavepackets originating from pure rotational states are created by a femtosecond stimulated rotational Raman interaction. The two Raman responses are instantly probed by a single-mode ns pulse generating two interfering RCARS polarizations. The resulting sign

DETERRENCE BY DENIAL AND RESILIENCE BUILDING

Deterrence and resilience are intimately connected. Deterrence is about understanding threats and using levers that might force an adversary to reconsider their objectives and actions against you. Resilience is about understanding yourself and the measures you can take to become a less attractive target, or to bounce back more quickly from a setback. This combination of deterrence and resilience h

ASYMMETRICAL CONFLICT IN THE INFORMATION DOMAIN—THE CASE OF RUSSIA

The deteriorating security environment in Europe due to the increasing conflict of interests between western democracies and Russia is now, after the Russian invasion of Ukraine, obvious to all. But the willingness of the Russian state to oppose and disrupt European security order and the sovereignty of other states is not new. One increasingly common way is using influence operations, often in co

A sense of seaweed : Consumer liking of bread and spreads with the addition of four different species of northern European seaweeds. A pilot study among Swedish consumers.

Current food systems pose one of the greatest health and environmental challenges of the 21st century. Expanded utilization of seaweed for food in Western societies seems like one promising measure in the transition toward sustainable food systems. However, introducing and expanding seaweed to new markets brings certain challenges, such as limited food acceptance and availability. In this pilot coCurrent food systems pose one of the greatest health and environmental challenges of the 21st century. Expanded utilization of seaweed for food in Western societies seems like one promising measure in the transition toward sustainable food systems. However, introducing and expanding seaweed to new markets brings certain challenges, such as limited food acceptance and availability. In this pilot co

Postmigrant Talks Experiences of Language Use in Swedish Academia Academic Migrants in Sweden

The authors take on a problem that many departments in Sweden, not least in the humanities, are dealing with right now: language. They show how social status in academia is decoupled from linguistic integration, at least if we understand status in terms of academic titles. Feelings of insufficiency and incompleteness are, however, prevalent, even among those whose Swedish proficiency is objectivel

Spina bifida global learning collaborative : Educating the next generation of clinicians, researchers, and advocates

PURPOSE: This project aimed to launch an international learning community to guide the development of a spina bifida (SB) curriculum for global health trainees.METHODS: Using a descriptive study design, a convenience sample of SB curricula were identified in 2022-23 by members of the Spina Bifida World Congress Outreach Committee and evaluated during a series of monthly Zoom calls to discuss SB ed

Engaging in Societal Collaboration Through Reflexivity : Experiences from a Cross-Disciplinary Pilot Course for Faculty

There is limited understanding of how education initiatives geared toward faculty and support staff can foster a capacity for long-term and integrated societal engagement and collaboration within higher education institutions. Using the experiences from a cross-disciplinary pilot course in Sweden, the current study aims to identify features that explicate how skills and academic rigor for engagingThere is limited understanding of how education initiatives geared toward faculty and support staff can foster a capacity for long-term and integrated societal engagement and collaboration within higher education institutions. Using the experiences from a cross-disciplinary pilot course in Sweden, the current study aims to identify features that explicate how skills and academic rigor for engaging

Co-designing with extreme users : a framework for user participation in design processes

The demand for user participation in design processes is increasing, and there is a need to formulate guidance on how to involve disabled users and their representative organisations. Their participation contributes an extreme user perspective to the design process. The aim of this study was to develop an empirically grounded framework for user participation in co-design processes, involving the u