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Vascular cellular adhesion molecule-1 (VCAM-1) expression in mice retinal vessels is affected by both hyperglycemia and hyperlipidemia.

BACKGROUND: Inflammation has been proposed to be important in the pathogenesis of diabetic retinopathy. An early feature of inflammation is the release of cytokines leading to increased expression of endothelial activation markers such as vascular cellular adhesion molecule-1 (VCAM-1). Here we investigated the impact of diabetes and dyslipidemia on VCAM-1 expression in mouse retinal vessels, as we

What Drives Exports? Empirical Evidence at the Firm Level

The aim of this thesis is to the understand how firms engage in exporting, particularly in consideration of three aspects—product type, past trade experience, and investments in innovation activities. It consists of one introductory chapter and three independent papers relating to determinants of firms’ exporting. Chapter 2 investigates the distance effect on the exporting of homogeneous and diff

Psykisk ohälsa, folkhälsa och medikalisering: har det egentligen någon betydelse vilket hälsobegrepp som används? [Poor mental health, public health and medicalization: is it of any significance which health concepts are used?].

The World Health Organization suggests mental ill health in terms of depres- sion soon to be the highest-ranking disease problem in the Western part of the world. However, some critics argue that the alarming reports on mental ill health have their ground in the methods of inquiry themselves and refer to medicalization as an important issue. The aim of this article is to explore and illuminate the

Disease status, costs and quality of life of patients with rheumatoid arthritis in France: The ECO-PR Study.

OBJECTIVE: To investigate resource consumption and quality of life (utility) in a sample of patients covering the full spectrum of the disease, modalities of patient management and geographic areas. METHODS: Information on demographics, disease parameters, work capacity and resource consumption (in the past 1, 3 or 12months depending on the resource) was collected in an anonymous mail survey from

Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.

BACKGROUND: The Tensin family of intracellular proteins (Tensin1, -2, -3 and -4) are thought to act as links between the extracellular matrix and the cytoskeleton, and thereby mediate signaling for cell shape and motility. Dysregulation of Tensin expression has previously been implicated in human cancer. Here, we have for the first time evaluated the significance of all four Tensins in a study of