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Allergic contact dermatitis from octylisothiazolinone

BACKGROUND: Octylisothiazolinone is a biocide that has been reported as a moderate, but rare contact allergen.OBJECTIVES: To investigate the occurrence of octylisothiazolinone contact allergy and allergic contact dermatitis diagnosed and registered in the Allergen Bank at Odense University Hospital during the past 20 years. Octylisothiazolinone has been used for targeted testing only.METHOD: All o

Risk Factors for Long-Term Contracture Recurrence after Collagenase Injection for Dupuytren Disease : A Prospective Cohort Study

In Dupuytren disease, little is known about the long-term outcomes of collagenase injection or risk factors for contracture recurrence. In this prospective study, 159 patients (242 fingers) with Dupuytren disease and active extension deficit (AED) ≥20° in a metacarpophalangeal (MCP) or proximal interphalangeal (PIP) joint were treated with collagenase injection during a 14-month period. At 5 years

Occupational contact dermatitis in painters : an analysis of patch test data from the Danish Contact Dermatitis Group

BACKGROUND: Painters are among the occupational groups that most commonly experience occupational contact dermatitis, but few investigations exist concerning this occupation.OBJECTIVES: To characterize painters with contact dermatitis and identify the most common allergens associated with the occupation. Materials and methods. All patch test results of 219 painters and 1095 matched controls regist

The influence of acetylsalicylic acid and alcohol on absorption kinetics of hen´s egg white in a human passive cutaneous anaphylaxis model

Background: Despite the well-known fact that acetylsalicylic acid (ASA) can induce anaphylaxis in patients susceptible to wheat-dependent exercise-induced anaphylaxis, few studies have sought to investigate the effects of cofactors on type-1 food allergy and none with ASA and hen’s egg and hen’s egg and alcohol combined. Methods and results: We applied the experimental model of ‘passive cutaneous

Antiviral treatment of a boy with EBV-associated hydroa vacciniforme

Hydroa vacciniforme is one of the rarest forms of photosensitivity disorders of the skin. Effective treatment options are scarce and mainly constitute of strict sun protection. Lately, hydroa vacciniforme has been associated with Epstein-Barr virus infection. We present a patient with hydroa vacciniforme and concomitant previous/chronic Epstein-Barr virus infection. In this case, antiviral treatme

The quest for ingested peanut protein in human serum

BACKGROUND: There is mounting evidence that systemic uptake of food allergens is key to triggering anaphylaxis. However, direct proof for this theory is still lacking. The purpose of this study was to quantify the absorption and to determine the absorption kinetics of immunoreactive peanut protein in relation to the allergic response in human.METHODS: Quantitative protein assays including mass spe

Effects of hypoxia on bronchial and alveolar epithelial cells linked to pathogenesis in chronic lung disorders

Introduction: Chronic lung disorders involve pathological alterations in the lung tissue with hypoxia as a consequence. Hypoxia may influence the release of inflammatory mediators and growth factors including vascular endothelial growth factor (VEGF) and prostaglandin (PG)E 2. The aim of this work was to investigate how hypoxia affects human lung epithelial cells in combination with profibrotic s

Modifying effect of gender on the prognostic value of clinicopathological factors and Ki67 expression in melanoma : a population-based cohort study

BACKGROUND: Malignant melanoma is the most deadly form of skin cancer. Female sex is known to have a protective effect on incidence, tumour characteristics, and mortality from melanoma. However, the potentially modifying effect of sex on the prognostic significance of clinicopathological and investigative factors is generally not taken into consideration in biomarker studies. In this study, we com

Modelling of motorcyclists' risky behaviour at an urban T-junction using generalised linear model : An exploratory study

Motorcyclists represent the greatest share of recorded traffic crashes and fatalities in Malaysia. The association between motorcyclists' behaviour and traffic conflict occurrence was assessed at a typical stop-regulated T-Junction in an urban area of Kuala Lumpur, Malaysia. Traffic activities were filmed over four months and the behaviour of motorcyclists entering the main road from the minor roa

Agreement and reliability of hepatic transient elastography in patients with chronic hepatitis C : A cross-sectional test-retest study

BACKGROUND AND AIMS: Transient elastography (TE) has largely replaced liver biopsy to evaluate fibrosis stage and cirrhosis in chronic hepatitis C. Previous studies have reported excellent reliability of TE but agreement metrics have not been reported. This study aimed to assess interrater agreement and reliability of repeated TE measurements.METHODS: Two operators performed TE independently, dire

High gas tightness ZrO2-added silicate glass sealant with low thermal stress for solid oxide fuel cells

A low leakage rate sealant of 10 wt% ZrO2-added CaO–K2O–Na2O–BaO silicate glass for SOFC has been studied. The structure of the sealant is stable at high temperatures with leakage rates less than 10−4 sccm∙cm−1, and no crystal except for ZrO2 is found in XRD analysis after heating at 800 °C for 100 h. ZrO2 is distributed in the glass matrix and plays a supporting role in avoiding over-softening at

Bumblebee flower constancy and pollen diversity over time

Bees often focus their foraging effort on a few or even a single flower species, even if other equally rewarding flower species are present. Although this phenomenon-called flower constancy-has been widely documented during single foraging trips, it is largely unknown if the behavior persists over longer time periods, especially under field conditions with large temporal variations of resources. W

Stabilization of evanescent wave propagation operators

This paper presents a stabilized scheme that solves the wave propagation problem in a general bianisotropic, stratified medium. The method utilizes the concept of propagators, i.e., the wave propagation operators that map the total tangential electric and magnetic fields from one plane in the slab to another. The scheme transforms the propagator approach into a scattering matrix form, where a spec

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Sagsbehandlerne i forvaltningen skal træffe afgørelser på et oplyst og objektivt grundlag og være i stand til at begrunde afgørelserne. De assisteres dog i stigende grad af beslutningsunderstøttende algoritmer, der er skabt til at generere output fremfor at tilvejebringe en forklaring. Denne udvikling kan effektivisere og for-bedre arbejdsgange, men kan også udfordre forvaltningsretlige krav til s