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Prokaryotic Argonaute proteins (pAgos) from the long-A clade are stand-alone immune systems that use small interfering DNA (siDNA) guides to recognize and cleave invading plasmid and virus DNA. Certain long-A pAgos are co-encoded with accessory proteins with unknown functions. Here, we show that cyanobacterial long-A pAgos act in conjunction with Argonaute-associated Cas4 family enzyme 1 (ACE1). S
We propose a dynamical model depicting nitrogen (N2) fixation (diazotrophy) in a unicellular cyanobacterium, Crocosphaera watsonii, grown under light limitation and obligate diazotrophy. In this model, intracellular carbon and nitrogen are both divided into a structual pool and a storage pool. An internal pool that explicitly describes the nitrogenase enzyme is also added. The model is successfull
A novel bacterial strain, MSB163, was isolated from the stool sample of a healthy mother, 4 weeks after giving birth via vaginal delivery. Taxonomic identification tools revealed that MSB163 belongs to the genus Bacteroides, but it is distinct from any currently known species. The closest related species is Bacteroides cellulosilyticus strain BFG- 250, with an average nucleotide identity (fastANI)
While the importance of breastfeeding on the developing infant gut microbiota has been established, few studies have compared the effect of breastfeeding duration on infant gut microbiota development. In this pilot study, we included 23 infants, divided into 4 groups to compare the effect of breastfeeding duration for first 4 (BreastFed_4) or 8 weeks (BreastFed_8) compared to exclusive breast
What impact did the process of Romanization have on the landscapes and territories of ancient Hispania? This book examines the transformations of Baetica through a rigorous study of Western Sierra Morena and the Lands of Antequera, two key regions for understanding this historical period.The research adopts an innovative perspective that integrates spatial analysis and landscape study to examine t
Fibromyalgia is a chronic syndrome characterized by pain, fatigue, and cognitive disturbances. The increased prevalence of contact allergy to gold in individuals with fibromyalgia when compared with the general population has previously been described. Gold contact allergy can manifest as a systemic contact dermatitis, with cutaneous and extracutaneous manifestations presenting upon systemic admin
Double diffusion encoding (DDE) makes diffusion MRI sensitive to a wide range of microstructural features, and the acquired data can be analysed using different approaches. Correlation tensor imaging (CTI) uses DDE to resolve three components of the diffusional kurtosis: isotropic, anisotropic, and microscopic kurtosis. The microscopic kurtosis is estimated from the contrast between single diffusi
Bioenergi spelar idag en stor roll i det svenska energisystemet ur klimat- och energisäkerhetssynpunkt men vilken roll kan inhemsk bioenergi komma att spela framöver för att Sverige ska bli ett fossilfritt samhälle med nettonollutsläpp 2050? Syftet med denna rapport är att utifrån olika perspektiv beskriva hur tillförseln av inhemska skogsbaserade biobränslen kan komma att förändras under perioden
With the rapid process of urbanization, water conflicts between different water use industries and areas are increasing. Therefore, China has implemented the three-cordons system of water resources management since 2012, when how to make more reasonable regulation of water resources became an urgent problem in most areas of China. In this study, taking the Yuanhe River Basin as an example, an inte
Ett antologikapitel om hur den tekniska utvecklingens samhällspåverkan beskrivs inom nationalekonomi respektive teknikhistoria samt hur begreppet stigberoende kan användas för att sammanföra de två perspektiven.
Drawing on vignette interviews, this article analyses the legal consciousness of disability anti-discrimination law of staff working with disability/accessibility resources in higher education in Sweden and the United States. In both countries, participants considered the law as the basis of their work, but differences were noticed regarding their views of the purpose of laws banning disability di
PurposeLeucine rich alpha-2 glycoprotein 1 (LRG1) has emerged as a promising biomarker for appendicitis, especially in pediatric patients. However, the currently available data are sparse, and the biomarker must be validated in more settings and compared to standard inflammatory markers. We aimed to evaluate the diagnostic and discriminative utility of serum and urine LRG1 in children with other c
Businesses play a key role in transforming production and consumption for sustainability,where circular business models (CBMs) offer one solution to reduce waste and rethink resource use.Although CBMs may be able to provide environmental and economic benefits, it is unclear how they canbe implemented effectively and contribute to sustainability goals. To understand how CBMs cancontribute to broade
Die Teilhabe am Arbeitsmarkt spielt in modernen Gesellschaften eine zentrale Rolle. Die Sicherung des Lebensunterhalts und die soziale Sicherung sind in starkem Maße von der Positionierung auf dem Arbeitsmarkt abhängig. Auch in der Migrationsforschung wird daher die Arbeitsmarktplatzierung von Migranten als zentraler Aspekt der Integration in die Aufnahmegesellschaft betrachtet. Für die Migranten
