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New constraints on the chemical evolution of the solar neighbourhood and Galactic disc(s) Improved astrophysical parameters for the Geneva-Copenhagen Survey

We present a re-analysis of the Geneva-Copenhagen survey, which benefits from the infrared flux method to improve the accuracy of the derived stellar effective temperatures and uses the latter to build a consistent and improved metallicity scale. Metallicities are calibrated on high-resolution spectroscopy and checked against four open clusters and a moving group, showing excellent consistency. Th

Computationally Efficient Sparsity-Inducing Coherence Spectrum Estimation of Complete and Non-Complete Data Sets

The magnitude squared coherence (MSC) spectrum is an often used frequency-dependent measure for the linear dependency between two stationary processes, and the recent literature contain several contributions on how to form high-resolution data-dependent and adaptive MSC estimators, and on the efficient implementation of such estimators. In this work, we further this development with the presentati

Zero products of Toeplitz operators

We prove that the product of finitely many Toeplitz operators oil the Hardy space is zero if and only if at least one of the operators is zero. We use some new vector-valued techniques that not only lead to a vector-valued version of this result but also appear to be needed in the scalar case.

Vélomobility - A critical analysis of planning and space

The purpose of this doctoral study is to bring a spatial dimension into the research on urban mobilities and connect the spatial dimension to the marginalisation of cyclists in urban space. This is been done by exploring the role of urban bicycling and transport planning. The theoretical frame of space, mobilities and power is used for analysing that role through case studies in two Scandinavian c

Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet

Patients with coeliac disease living on a gluten-free diet show vitamin deficiency and reduced subjective health status. To study the biochemical and clinical effects of B vitamin supplementation in adults with longstanding coeliac disease. In a double blind placebo controlled multicentre trial, 65 coeliac patients (61% women) aged 45-64 years on a strict gluten-free diet for several years were ra

Enacting knowledge exchange : a context dependent and ‘role-based’ typology for capturing utility from university research

One of the key research and policy problems in innovation studies is the development of tools for understanding and measuring the impact of academic research on society. The paper contributes to resolving this problem by providing a typology that helps us to understand and analyse the roles researchers take on in order to make academic knowledge useful. A key finding is that utility creation is co

A combined small- and wide-angle x-ray scattering detector for measurements on reactive systems

A detector with high dynamic range designed for combined small-and wide-angle x-ray scattering experiments has been developed. It allows measurements on single events and reactive systems, such as particle formation in flames and evaporation of levitating drops. The detector consists of 26 channels covering a region from 0.5 degrees to 60 degrees and it provides continuous monitoring of the sample

Genetic Variants of Coagulation Factor XI Show Association with Ischemic Stroke Up to 70 Years of Age

Background and Purpose: Coagulation factor XI (FXI) has an important role in the propagation and stabilization of a thrombus upon vessel injury. High FXI levels have been implicated in thrombotic diseases including ischemic stroke. The aim of our study was to investigate whether FXI gene (F11) variants are associated with ischemic stroke. Methods: The discovery sample, the Sahlgrenska Academy Stud

Use of a standardized diagnostic approach improves the prognostic information of histopathologic factors in pancreatic and periampullary adenocarcinoma.

Variability in reported histopathology parameters in operated periampullary adenocarcinomas may affect the prognostic weight of the parameters. Standardized axial sectioning produces a higher incidence of involved margins and also seems to produce a lower relative incidence of pancreatic compared with distal bile duct origin and a higher incidence of involved lymph nodes, compared with non-standar

Heavy-element fission barriers

We present calculations of fission properties for heavy elements. The calculations are based on the macroscopic-microscopic finite-range liquid-drop model with a 2002 parameter set. For each nucleus we have calculated the potential energy in three different shape parametrizations: (1) for 5 009 325 different shapes in a five-dimensional deformation space given by the three-quadratic-surface parame

Centrality and rapidity dependence of inclusive jet production in root(NN)-N-S=5.02 TeV proton-lead collisions with the ATLAS detector

Measurements of the centrality and rapidity dependence of inclusive jet production in root(NN)-N-S = 5.02 TeV proton-lead (p + Pb) collisions and the jet cross-section in root s = 2.76 TeV proton-proton collisions are presented. These quantities are measured in datasets corresponding to an integrated luminosity of 27.8 nb(-1) and 4.0 pb(-1), respectively, recorded with the ATLAS detector at the La

Regulation of Hematopoietic Stem Cells

Popular Abstract in Swedish Det finns celler i vår kropp som har ett livslångt ansvar att tillverka alla blodceller. De kallas blodstamceller, eller hematopoetiska stamceller, och är en till antalet liten population celler som har den enorma kapaciteten att göra 1012 blodceller om dagen under hela vårt liv. Blodstamceller har multipotentiell differentieringsförmåga dvs. de kan bilda alla mogna bloThis thesis is about the regulation of hematopoietic stem cells (HSCs) that represent rare cells residing in the bone marrow (BM) of adults. They are multipotent cells that have the capacity to differentiate to all mature cells of the blood system and have the capacity to self-renew, i.e. generate new HSCs. These cells have tremendous therapeutic potential to treat a variety of hematopoietic disor

High modal number and triple trisomies are highly correlated favorable factors in childhood B-cell precursor high hyperdiploid acute lymphoblastic leukemia treated according to the NOPHO ALL 1992/2000 protocols

Between 1992 and 2008, 713 high hyperdiploid acute lymphoblastic leukemias in children aged 1-15 years were diagnosed and treated according to the Nordic Society for Pediatric Hematology and Oncology acute lymphoblastic leukemia 1992/2000 protocols. Twenty (2.8%) harbored t(1;19), t(9; 22), der(11q23), or t(12; 21). The median age of patients with "classic" high hyperdiploidy was lower than that o

The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist

Neutrophils interacting with a chemoattractant gradually become nonresponsive to further stimulation by the same agonist, a process known as desensitization. Receptor desensitization is a highly regulated process that involves different mechanisms depending on which receptor-ligand pair that is studied. Galectin-3, a member of a large family of beta-galactoside-binding lectins, has been suggested

Tiger en svensk? Tystnader om tysk nationalsocialism i svensk press och i Svenska kyrkan 1933–1939

This inaugural lecture in the Royal Swedish Academy of Letters, History and Antiquities discusses the silence in Swedish press and in the Church of Sweden on National socialism, 1933-1939. This silence was neither common nor general, it was often concentrated to certain levels or matters. Silence could be compact, while the silent persons could speak on other levels, in other words, often in a the

Resonant inelastic x-ray scattering and UV-VUV luminescence at the Be 1s edge in BeO

We carried out a combined study of UV-VUV luminescence and resonant x-ray emission from BeO single crystals with incident photon energies in the vicinity of the Be 1s absorption edge. The x-ray emission spectra show that at the Be 1s photoabsorption edge the lattice relaxation processes in the excitation site take place already on the timescale of the radiative decay of the core excitation. Compar

Increased plasma apoM levels in the patients suffered from hepatocellular carcinoma and other chronic liver diseases

Objective: To determine plasma apolipoprotein M ( apoM) levels and other lipid profiles in hepatocellular carcinoma ( HCC) patients compared to other chronic liver diseases and normal subjects. Materials and methods: 36 HCC, 68 chronic hepatitis, 29 liver cirrhosis patients and 64 normal controls were subjected in the present study. Serum lipids, lipoproteins, apolipoprotein AI ( apoAI) and apoB w

Thermal stability of vanadia SCR catalysts for the use in diesel applications

The effect of reaction temperature, water content, and vanadia content on the sintering of a model vanadia on silica-titania SCR catalysts has been investigated. A comparison is also made to a monolithic vanadia/titania catalyst submitted to conditions simulating at least 500,000 km driving on a diesel truck. The variation of the surface area, the pore structure and the crystallite size of the cat

Comparison of Negative Valve Overlap (NVO) and Rebreathing Valve Strategies on a Gasoline PPC Engine at Low Load and Idle Operating Conditions

Gasoline partially premixed combustion (PPC) has the potential of high efficiency and simultaneous low soot and NOx emissions. Running the engine in PPC mode with high octane number fuels has the advantage of a longer premix period of fuel and air which reduces soot emissions. The problem is the ignitability at low load and idle operating conditions. In a previous study it was shown that it is po