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Hematologic malignancies are characterized by fusion genes of biological/clinical importance. Immortalized cell lines with such aberrations are today widely used to model different aspects of leukemogenesis. Using cDNA microarrays, we determined the gene expression profiles of 40 cell lines as well as of primary leukemias harboring 11q23/MLL rearrangements, t(1;19)[TCF3/PBX1], t(12;21)[ETV6/RUNX1]
Background, Aims and Scope. Using renewable feedstock and introducing biocatalysts in the chemical industry have been suggested as the key strategies to reduce the environmental impact of chemicals. The Swedish interdisciplinary programme 'Greenchem', is aiming to develop these strategies. One target group of chemicals for Greenchem are wax esters which can be used in wood surface coatings for woo
Den elektroniska revolutionen har satt gränsen mellan original och kopia i fråga. Musikindustrin har därför drabbats av ett akut problem, för vem har rätt till vad när upphovsmannaskapet är oklart?
1. The spontaneous mechanical activity of guinea-pig mesotubarium consists of fused tetanic contractions lasting about 6 min, with a frequency of about four per hour. The muscle is completely relaxed between the contractions. Stretching the relaxed muscle elicits a contraction of the same appearance as the spontaneous ones. Comparison of preparations from oestrus (day 1 of the hormonal cycle), dio
The ground state properties and absorption spectra of N-benzylideneaniline (NBA) have been studied at the density functional (DFT) and at the time-dependent density functional (TD-DFT) level of the theory. The equilibrium geometries of the E and Z isomers in the ground state and their vibrational frequencies have been computed. Furthermore, the excitation energies of the lowest excited singlet and
The Low-Energy Undulator Test Line (LEUTL) at the Advanced Photon Source, Argonne National Laboratory, is intended to demonstrate the basic operation of a SASE-based free-electron laser. Goals include comparison of experimental results With theoretical predictions and scaling laws, identification of problems relevant to fourth-generation light source construction and operation and the means of add
The Internet contains scientific information in increasing amounts. It is possible to obtain the latest information, and Web services can easily be maintained and updated. We have set up three Internet ser vices an immunodeficiencies. Immunodeficiency-related mutation information is available in immunodeficiency mutation databases (IDbases). Currently 14 registries are distributed, including infor
Genetic engineering has been used to construct fusion proteins with tryptophan containing peptides. The peptides and the fusion proteins have been partitioned in aqueous two-phase systems of poly(ethylene glycol) (PEG)-dextran and Ucon-dextran. The studied model protein was ZZT0, where Z is an engineered domain of domain B of staphylococcal protein A. The specially designed hydrophobic peptides, A
Analyses of their internal stellar kinematics imply that the dwarf spheroidal (dSph) companion galaxies to the Milky Way are among the most dark matter-dominated systems known. Should there be significant dark matter in the form of faint stars in these systems, the stellar luminosity function must be very different from that of a similar metallicity globular cluster, for which there is no evidence
Variability in solute transport properties in the unsaturated zone is of growing concern due to environmental hazards. By combining dye and salt tracers, a detailed description of the solute transport can be made in both time and space. In this paper, qualitative and quantitative effects of preferential flow were investigated in a sandy loam. The experimental site was equipped with 64 TDR probes.
We used video recording of the movement pattern of Protaphorura armata (Collembola) to test whether its avoidance of the odor of dead conspecifics extends to related species. P. armata was repelled by the odor of dead individuals of Onychiurus scotarius and Onychiurus circulans, but not by live individuals. Free palmitic, oleic, and linoleic acids were present in extracts of the three repellent sp
The surface tension of adipic aqueous solution has been measured as a function of temperature (T = 278-313 K) and adipic acid mole fraction (X = 0.000-0.003) using the Wilhelmy plate method. A parameterization fitted to these data is presented. The evaporation rates of binary water-malonic and water-adipic acid droplets have been measured with a TDMA-technique at different temperatures (T = 293-30
Ingmar Brohed var 1978-97 professor i kyrkohistoria vid Lunds universitet, därefter forskningschef vid Svenska kyrkans forskningsråd. Festskriften innehåller 26 artiklar som i huvudsak behandlar svensk och internationell kyrkohistoria från 1700-tal till sent 1900-tal, med perspektiv även från etnologi, historia, kyrkovetenskap, missionsvetenskap, religionssociologi och rättshistoria. De speglar på
Wegener granulomatosis (WG) and microscopic polyangiitis (MP), diseases associated with antineutrophil cytoplasmic antibodies (ANCA), had an extremely poor prognosis before the introduction of cyclophosphamide and corticosteroids for their treatment. However, there is still reduced patient survival, and some studies have documented severe side effects of the immunosuppressants used. This 10-yr fol
Abstract is not available.
Popular Abstract in Swedish Bomärken har använts som ägarbeteckning och signatur i Norden in på 1800-talet, och i vissa reliktområden intill nutid. Bomärkena återfinns t.ex. i mantalslängder, jordaböcker och bouppteckningar, men även inskurna på äldre redskap, husgeråd och annat lösöre. Bomärkena har av somliga forskare ansetts ha utformats slumpvis, enbart med syftet att kunna skilja en bomärkesThe pioneering academic research on Merchant Marks (also known as identity marks, personal marks, ownership marks, identification marks, Hausmarken, Hofmarken, Marques de Propriété, bomärken) was done by professor Homeyer (1870). Since 1870 there has been an ongoing debate among scholars whether Merchant Marks are simply formed by chance and coincidence, as stated by Rehnberg (1938, 1951), Scheffe
