Search results

Filter

Filetype

Your search for "*" yielded 528606 hits

Decreased migration with locally administered bisphosphonate in cemented cup revisions using impaction bone grafting technique : A randomized, controlled study evaluated with RSA and DXA with a 2-year follow-up

Background and purpose — Impaction bone grafting (IBG) in revision hip surgery is an established method in restoring bone stock deficiencies. We hypothesized that local treatment of the morsellized allograft with a bisphosphonate in cemented revision would, in addition to increased bone density, also reduce the early migration of the cup as measured by radiostereometry (RSA). Patients and methods

No long-term risk of wrist osteoarthritis due to subchondral haematomas in distal radial fractures

Objective: The objective of this study of distal radius fractures was to determine if a subchondral haematoma in an unfractured compartment predicts secondary osteoarthritis. Methods: In 1995–1997, 41 patients, 22 women, a median age of 41 years (20–57 years) with a displaced distal radius fracture underwent diagnostic wrist arthroscopy in addition to the fracture treatment. In 12 patients (7/12 w

Development of ACRODAT®, a new software medical device to assess disease activity in patients with acromegaly

Purpose: Despite availability of multimodal treatment options for acromegaly, achievement of long-term disease control is suboptimal in a significant number of patients. Furthermore, disease control as defined by biochemical normalization may not always show concordance with disease-related symptoms or patient’s perceived quality of life. We developed and validated a tool to measure disease activi

Plasma enterolactone and risk of prostate cancer in middle-aged Swedish men

Purpose: Enterolactone (ENL) is formed in the human gut after consumption of lignans, has estrogenic properties, and has been associated with risk of prostate cancer. We examined the association between plasma ENL levels and prostate cancer in a nested case–control study within the population-based Malmö Diet and Cancer cohort. We also examined the association between plasma ENL and dietary and li

Hospital volume and the risk of revision in Oxford unicompartmental knee arthroplasty in the Nordic countries -an observational study of 14,496 cases

Background: High procedure volume and dedication to unicompartmental knee arthroplasty (UKA) has been suggested to improve revision rates. This study aimed to quantify the annual hospital volume effect on revision risk in Oxfordu? nicompartmental knee arthroplasty in the Nordic countries. Methods: 14,496 cases of cemented medial Oxford III UKA were identified in 126 hospitals in the four countries

Heparin-binding protein, lysozyme, and inflammatory cytokines in bronchoalveolar lavage fluid as diagnostic tools for pulmonary infection in lung transplanted patients

Pulmonary infection is a common complication after lung transplantation, and early detection is crucial for outcome. However, the condition can be clinically difficult to diagnose and to distinguish from rejection. The aim of this prospective study was to evaluate heparin-binding protein (HBP), lysozyme, and the cytokines interleukin (IL)-1β, IL-6, IL-8, IL-10 and tumor necrosis factor (TNF) in br

The vildagliptin experience - 25 years since the initiation of the novartis glucagon-like peptide-1 based therapy programme and 10 years since the first vildagliptin registration

The discovery of the incretin hormone glucagon like peptide-1 (GLP-1), and its usefulness in the treatment of type 2 diabetes mellitus (T2DM) followed by the finding that dipeptidyl peptidase-4 (DPP-4) inhibition prevents GLP-1 inactivation, led to the discovery of DPP-728. In 1999, studies with DPP-728 established the first proof-of-concept that DPP-4 inhibition improves glycaemic control in pati

Interventions for treating genital Chlamydia trachomatis infection in pregnancy

Background: Genital Chlamydia trachomatis (C.trachomatis) infection may lead to pregnancy complications such as miscarriage, preterm labour, low birthweight, preterm rupture of membranes, increased perinatal mortality, postpartum endometritis, chlamydial conjunctivitis and C.trachomatis pneumonia.This review supersedes a previous review on this topic. Objectives: To establish the most efficacious

Search for new phenomena in a lepton plus high jet multiplicity final state with the ATLAS experiment using √s=13 TeV proton-proton collision data

A search for new phenomena in final states characterized by high jet multiplicity, an isolated lepton (electron or muon) and either zero or at least three b-tagged jets is presented. The search uses 36.1 fb−1 of s=13 TeV proton-proton collision data collected by the ATLAS experiment at the Large Hadron Collider in 2015 and 2016. The dominant sources of background are estimated using parameterized

Structure of the SnO2 (110)- (4×1) Surface

Using surface x-ray diffraction (SXRD), quantitative low-energy electron diffraction (LEED), and density-functional theory (DFT) calculations, we have determined the structure of the (4×1) reconstruction formed by sputtering and annealing of the SnO2(110) surface. We find that the reconstruction consists of an ordered arrangement of Sn3O3 clusters bound atop the bulk-terminated SnO2(110) surface.

Boys have better short-term and long-term survival rates after intensive care admissions than girls

Aim: We investigated possible gender differences in paediatric intensive care morbidity-adjusted mortality. Methods: In this study, data on all 21 972 paediatric intensive care admissions in Sweden between 2008 and 2015 were analysed regarding morbidity-adjusted survival, using Cox regression, with age, gender and estimated mortality ratio as dependent variables and using the standardised mortalit

French version of the profiles of occupational engagement in people with severe mental illness : Translation, adaptation, and validation

Occupational engagement is affected in many persons with severe mental illness (SMI) because of personal, occupational, and environmental issues. However, no French assessment tool measuring occupational engagement in these persons is currently available. The objectives of the study were to translate the “Profiles of Occupational Engagement in People with Severe Mental Illness” (POES), including a

On Author, Copyright and Originality: does the unified EU originality standard correspond to the digital reality in Wikipedia?

This article is contributing to the future of copyright law debate by exploring the recently harmonised originality standard in the EU copyright law and its suitability to a creative sharing community of Wikipedia. It shows that the “free creative choices” and “author’s personal” touch criteria established by the CJEU might be unsuitable not only because of practical concerns, but also because the

Early Electroencephalography Suppression and Postnatal Morbidities Correlate with Cerebral Volume at Term-Equivalent Age in Very Preterm Infants

Background: Early brain activity is associated with long-term outcome. Establishing a relation also with postnatal brain growth may increase our understanding of early life influences on preterm brain development. Objectives: The aim of this study was to investigate whether early electroencephalography (EEG) activity in infants born very preterm is associated with brain volumes at term, and whethe

Multiple stressors in rotifer communities: : Effects of predation, climate change, and brownification

De flesta vattenlevande organismer på Jorden lever i en miljö där de samtidigt måste hantera flera olika hot och stressituationer, såsom t.ex. predation, klimatförändringar och brunifiering. Trots relativt god kunskap om varje stressfaktor för sig, vet man förvånansvärt lite om hur synergier av samtidigt förekommande hot påverkar organismer. Därför har jag i min avhandling undersökt hur predation,Most organisms on Earth live in an environment where they are exposed to multiple pressures, including predation and climate change. In many aquatic ecosystems, organisms have to handle additional challenges such as brownification, co-occurring with climate warming. Despite the growing recognition of impacts of climate warming or brownification on the freshwater communities, little is known on how

Cognitive functioning following one-year natalizumab treatment : A non-randomized clinical trial

Objectives: Cognitive impairment is common in multiple sclerosis (MS) and can have serious impact on social and occupational functioning. Natalizumab reduces relapse rates, magnetic resonance imaging (MRI) lesions, and progression of disability. Previous studies on cognitive functioning have not based inclusion on cognitive performance criteria. The aim of the present study was to determine any po