A challenging question in evolutionary theory is the origin of cell division and plausible molecular mechanisms involved. Here, we made the surprising observation that complexes formed by short alpha-helical peptides and oleic acid can create multiple membrane-enclosed spaces from a single lipid vesicle. The findings suggest that such complexes may contain the molecular information necessary to in

In compressed sensing a sparse vector is approximately retrieved from an underdetermined equation system Ax = b. Exact retrievalwouldmean solving a large combinatorial problem which is well known to be NP-hard. For b of the form Ax0 + ϵ, where x0 is the ground truth and ϵ is noise, the 'oracle solution' is the one you get if you a priori know the support of x0, and is the best solution one could h

Nasopharyngeal cancer (NPC) features intralesional immune cells, but data are lacking on presence/distribution of T-cells and dendritic cells (DCs). Based on intralesional distribution of lymphocytes, a series of NPC biopsies (n = 48) were classified into “inflamed”, “excluded”, and “deserted” phenotypes. In addition, CD8+ T-cells and CD207+ DCs were quantified. The data were analyzed in relation

African countries such as Nigeria are anticipated to be more susceptible to the impacts of climate change due to large dependence on rainfed agriculture and to several uncertainties in the responses of crop production to climate change. The impacts of climate change on crop water requirements (CWR), irrigation water requirements (IWR), yields and crop water productivity (CWP) of rainfed maize in O

Background: Occupational balance (OB) is an important concept in occupational therapy and is considered as an essential component of health and well-being. Aim: The aim of this study was to investigate the validity and reliability of the Turkish version of the Occupational Balance Questionnaire-11 (OBQ11-T). Materials and methods: The OBQ11-T was administered to 116 individuals for construct valid

BACKGROUND: Positive photopatch test reactions are classified according to the International Contact Dermatitis Group. The various reaction patterns are interpreted to represent patterns such as contact allergy, photocontact allergy, photoaugmentation, and photoinhibition. OBJECTIVE: To investigate whether there are any weaknesses in the interpretation of reaction patterns. MATERIALS & METHODS

Background/aims: Intestinal permeability with systemic distribution of bacterial products are central in the immunopathogenesis of alcoholic liver disease (ALD), yet links with intestinal immunity remain elusive. Mucosa-associated invariant T cells (MAIT) are found in liver, blood and intestinal mucosa and are a key component of antibacterial host defences. Their role in ALD is unknown. Methods/de

Background: Anterior resection has the benefit of enabling bowel continuity, but suffer from a common complication in anastomotic leakage.There is a paucity in previous research of long-term implications of anastomotic leakage after anterior resection.Aims: To gain general knowledge of the morbidity related to anastomotic leakage after anterior resection for rectal cancer, specific aims were:I. ToBackground: Anterior resection has the benefit of enabling bowel continuity, but suffer from a common complication in anastomotic leakage.There is a paucity in previous research of long-term implications of anastomotic leakage after anterior resection.Aims: To gain general knowledge of the morbidity related to anastomotic leakage after anterior resection for rectal cancer, specific aims were:I.To

Objective: An artefact-free electrocardiogram (ECG) is essential during cardiac arrest to decide therapy such as defibrillation. Mechanical cardiopulmonary resuscitation (CPR) devices cause movement artefacts that alter the ECG. This study analyzes the effectiveness of mechanical CPR artefact suppression filters to restore clinically relevant ECG information. Approach: In total, 495 10 s ECGs were

Between 2014 and 2019, an innovative small-pyrolysis system (the PPV300) using agrowaste as feedstock was transferred and adapted from Switzerland to Vietnam by a United Nations Industrial Development Organization (UNIDO) project. The coffee husk resulting from the processing of coffee beans is usually disposed of in Vietnam or burned inefficiently to dry coffee beans. Small-scale pyrolysis of cof

Context. Previous studies of open clusters have shown that lithium depletion is not only strongly age dependent but also shows a complex pattern with other parameters that is not yet understood. For pre- and main-sequence late-type stars, these parameters include metallicity, mixing mechanisms, convection structure, rotation, and magnetic activity. Aims. We perform a thorough membership analysis f

Observed FeO/MgO ratios in the Moon and Earth are inconsistent with simulations done with a single homogeneous silicate layer. In this paper we use a newly developed equation of state to perform smoothed particle hydrodynamics simulations on the lunar-forming impact, testing the effect of a primordial magma ocean on Earth. This is investigated using the impact parameters of both the canonical case

In our solar system, terrestrial planets and meteoritical matter exhibit various bulk compositions. To understand this variety of compositions, formation mechanisms of meteorites are usually investigated via a thermodynamic approach that neglects the processes of transport throughout the protosolar nebula. Here, we investigate the role played by rocklines (condensation/sublimation lines of refract

Climate change affects human health in a myriad of ways, requiring reassessment of the nature of scaling up care delivery and the effect that care delivery has on the environment. 5 billion people do not have access to safe and timely surgical care, and the quantity and severity of conditions that require surgical, obstetric, and anaesthesia care will increase substantially as a result of climate

This article engages with the question of who our neighbour is, linked to the imperative of love thy neighbour, with the aim of a broadened understanding of who should be seen as a neighbour on an ontological level. First, drawing on posthumanistic theory and its critique of human anthropocentrism, as well as ascribing subjectivity and agency outside the human sphere, it seeks to put it into relat

A general transition to plant-based diets is recommended for improved human and planetary health. The information about why people opt for plant-based diets can be used to profile future health promotion initiatives. We studied the reasons that encouraged the adoption and maintenance of plant-based diets and the influence of the socio-cultural environment and other external factors. Through the us

Bioindication has become an indispensable part of water quality monitoring in most countries of the world, with the presence and abundance of bioindicator taxa, mostly multicellular eukaryotes, used for biotic indices. In contrast, microbes (bacteria, archaea and protists) are seldom used as bioindicators in routine assessments, although they have been recognized for their importance in environmen

The timing of influenza case incidence during epidemics can differ between regions within nations and states. We conducted a prospective 10-year evaluation (January 2008–February 2019) of a local influenza nowcasting (short-term forecasting) method in 3 urban counties in Sweden with independent public health administrations by using routine health information system data. Detection-of-epidemic-sta

An open-label, crossover randomized study was performed to compare the pharmacokinetics (PK) of damoctocog alfa pegol and rurioctocog alfa pegol, two recombinant factor VIII (FVIII) products indicated in patients with hemophilia A, both conjugated to polyethylene glycol to reduce clearance and extend time in circulation. Adult patients (N = 18) with severe hemophilia A (FVIII < 1 IU/dL), previousl