Vascular tissue consists of endothelial cells, vasoactive smooth muscle cells and perivascular nerves. The perivascular sensory neuropeptide CGRP has demonstrated potent vasodilatory effects in any arterial vasculature examined so far, and a local protective CGRP-circuit of sensory nerve terminal CGRP release and smooth muscle cell CGRP action is evident. The significant vasodilatory effect has sh

We assess the sustainability of rural electrification in Manica Province, Mozambique, focusing on different alternatives for mini-grid and off-grid power supply. The qualitative assessment considers four dimensions of sustainability, namely environmental, socio-cultural, economic, and institutional. We argue that small-scale hydropower is the most sustainable alternative for off-grid or mini-grid

Objective: To conduct a screening, skin examination and risk assessment of patients with pressure ulcers (PUs) in one Swedish county (inpatient, primary and community care) with follow-up after six months to investigate ulcer healing, frequency of amputation and mortality rate linked to preventive measures. Method: The methodology recommended by the European Pressure Ulcer Advisory Panel was used.

Objective: To describe the ultrasound features of different endometrial and other intracavitary pathologies inpre- and postmenopausal women presenting with abnormal uterine bleeding, using the International Endometrial Tumor Analysis (IETA) terminology. Methods: This was a prospective observational multicenter study of consecutive women presenting with abnormal uterine bleeding. Unenhanced sonogra

Students with neurodevelopmental disorders (NDDs) are present in every school, and most likely, there are a few students in every class. School health care is responsible for providing support to all students, especially those with special needs. The aim of the study was to describe school nurses’ experiences of supporting students with NDDs. A qualitative method consisting of seven focus group in

The Sun provides the principal energy input into the Earth system and solar variability represents a significant external climate forcing. Although observations of solar activity (sunspots) cover only the last about 400 years, radionuclides produced by cosmic rays and stored in tree rings or ice cores serve as proxies for solar activity extending back thousands of years. However, the presence of w

Selenium is an essential trace element involved in the body’s redox reactions. Low selenium intake during pregnancy has been associated with low birth weight and an increased risk of children being born small for gestational age (SGA). Based on data from the Norwegian Mother, Father and Child Cohort Study (MoBa) and the Medical Birth Registry of Norway (MBRN), we studied the association of materna

Therapeutic advances using targeted biologicals and small-molecule drugs have achieved significant success in the treatment of chronic allergic, autoimmune, and inflammatory diseases particularly for some patients with severe, treatment-resistant forms. This has been aided by improved identification of disease phenotypes. Despite these achievements, not all severe forms of chronic inflammatory and

Using different measures of how the Covid-19 pandemic progresses we find that the level of credit risk among US blue chip companies increases in tandem with the Covid-19 virus spreading. The credit risk increases dramatically during the pandemic, but we find it to be short of the levels seen during the 2008–2009 financial crisis. Furthermore, we find weekly ups and downs in credit risk and virus i

The lichen family Teloschistaceae from the Galapagos is revised. Most of the species belong to the Caloplacoideae, two to Teloschistoideae and a few to Xanthorioideae, three subfamilies not validly published, which is remedied here. Four different datasets were analyzed using Bayesian inference. For the bulk of the species, a combined dataset of nrITS, nrLSU and mrSSU was analyzed. Additionally, t

Objective:The relationship between fatigue and cognition has not been fully elucidated in children and adolescent survivors of brain tumours. The aim of the present study was to investigate the potential relationship between fatigue and cognitive impairments in these survivors, as this group is at risk for both types of deficits.Methods:Survivors of paediatric brain tumours (n = 45) underwent a ne

Based on molecular data, the austral lichen genus Austroplaca is shown to be represented in the Northern Hemisphere by the species Caloplaca sibirica. Accordingly, we make the combination Austroplaca sibirica. It grows on detritus and lignum in Canada, Greenland, Iceland, northern Scandinavia, Svalbard and Siberia and its southern range includes Patagonia (Argentina, Chile) and Kerguelen Islands.

This article is based on ethnographic fieldwork and applies theories of crafting and performance to explore how living heritage practices are rethought, reframed, and refashioned when traditional dress and individual garments are moved, reorganized, and transformed into a collection following rationales derived from both family tradition and museum standards. By following one woman’s emerging coll

BACKGROUND The results of a recent meta-analysis aroused concern about an increased risk of death associated with the use of paclitaxel-coated angioplasty balloons and stents in lower-limb endovascular interventions for symptomatic peripheral artery disease. METHODS We conducted an unplanned interim analysis of data from a multicenter, randomized, open-label, registry-based clinical trial. At the

We inventoried lichens in Kenai Fjords National Park in Alaska, USA We assembledthe known information on occurrence and ecology of lichens in this park by combiningfield, herbarium, and literature studies. Our results provide baseline data on lichenoccurrence that may be used in resource condition assessments, vulnerability assessments, long-term ecological monitoring, and resource management. We

Introduction: understanding motorcyclists’ on-the-road behaviour is critical for developing and evaluating interventions specifically targeting them. Risky on-the-road behaviours have historically been subdivided into errors and violations of the rules of road use. Police records could be used to record cyclists’ behaviours, however these documents do not necessarily capture all errors and violati

This theoretical paper defines and explores the concepts of transductive links and transductive chains, as part of the theoretical framework of social semiotics. Social semiotics stems from the multimodal framework, which provides a theoretical perspective, constructs, and a language to describe a shift of semiotic material within or between semiotic systems, such as rewriting a text or moving fro

Molecular analyses of the recently described Xanthoria polessica collected fromthe type locality and of the Australian species X. coomae were used to determine whether these taxa are distinct species or fall within the wide phenotypic variation of the wellknown and cosmopolitan X. parietina. Our results clearly indicate that both taxa should be considered as synonyms of X. parietina since the infr

Streptococcus pyogenes is a major human pathogen that causes a variety of diseases ranging from mild skin and throat infections to fatal septicemia. In severe invasive infections, S. pyogenes encounters and interacts with components of the extracellular matrix (ECM), including small leucine rich-proteoglycans (SLRPs). In this study, we report a novel antimicrobial role played by SLRPs biglycan, de