BACKGROUND: Most staging systems for soft tissue sarcoma are based on histologic malignancy-grade, tumor size and tumor depth. These factors are generally dichotomized, size at 5 cm. We believe it is unlikely that tumor depth per se should influence a tumor's metastatic capability. Therefore we hypothesized that the unfavourable prognostic importance of depth could be explained by the close associ

Asthma-like symptoms and bronchial hyper-responsiveness (BHR) to methacholine are prevalent in competitive cross-country skiers. Whether these symptoms (ski asthma) in these athletes are caused by asthma remains uncertain. Bronchial responsiveness to adenosine 5'-monophosphate (AMP) and nitric oxide (NO) concentration in exhaled air, both indirect markers of asthmatic airway inflammation, were inv

In the present study we demonstrate that all CD4+ T cells in human tonsil expressing the Th2-selective receptor chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) also 1) express high levels of CXCR5, and 2) display a transitional CD45RA/RO phenotype and consistently do not produce significant amounts of cytokines when immediately analyzed ex vivo. Hence, they represent pr

Popular Abstract in Swedish Psalmer som gav ?adekvata uttryck? åt motiven mission, evangelisation, diakoni, ekumenik, arbetsliv och ?ungdomens nya situation? efterlystes när arbetet med en ny psalmbok för Svenska kyrkan inleddes i slutet av 1960-talet. I avhandlingen visas att synen på de olika motiven påverkats av samhällets förändringar, särskilt under efterkrigstiden. Hur detta i sin tur återspThe dissertation treats the relation between hymn, hymn-book and society by studying six motifs in The Swedish Hymnal (Den svenska psalmboken): mission, evangelization, diaconia, ecumenics, working life and "the new situation of youth". In the latest revision of The Swedish Hymnal, 1969-1986, hymns that gave adequate expression to these motifs were especially sought for. The dissertation demonstra

1. The glucose and ATP dependence of exocytosis were investigated in single mouse pancreatic B-cells by monitoring changes in cell capacitance evoked by voltage-clamp depolarizations, infusion of high [Ca2+]i buffers or photorelease of caged Ca2+ or ATP. 2. In intact B-cells, using the perforated patch whole-cell technique, glucose (5 mM) increased exocytotic responses evoked by membrane depolariz

Four different oligosaccharides were isolated from faeces collected from a blood group A, secretor, breast-fed infant. Three of these, GalNAc alpha 1-3[Fuc alpha 1-2]Gal beta 1-4Glc (A-tetrasaccharide), GalNAc alpha 1-3[Fuc alpha 1-2]Gal beta 1-4[Fuc alpha 1-3]Glc (A-pentasaccharide) and 1-3[Fuc alpha 1-4]GlcNAc beta 1-3Gal beta 1-4Glc (A-heptasaccharide) have previously found in urine, whereas Ga

OBJECTIVE: Cardiac surgery with cardiopulmonary bypass elicits a systemic inflammatory response. An exaggerated response is associated with organ dysfunction and increased morbidity and mortality. DESIGN: The aim of the present study was to investigate whether the cardiopulmonary bypass procedure in itself results in accumulation of isotope-labeled platelets, polymorphonuclear neutrophils, and fib

Noroviruses (formerly Norwalk-like viruses) are a major cause of acute gastroenteritis worldwide and are associated with a significant number of nosocomial and food-borne outbreaks. In this study we show that the human secretor FUT2 gene, which codes for an alpha(1,2)-fucosyltransferase synthesizing the H-type 1 antigen in saliva and mucosa, is associated with susceptibility to norovirus infection

A simulation study to evaluate the required computing resources for a research exploitation of the Large Hadron Collider (LHC) has been performed. The evaluation,vas done as a case study. assuming existence of a Nordic regional centre and using the requirements for per-forming a specific physics analysis as a yard-stick. Other input parameters were: assumption for the distribution of researchers a

A group of 200 psychiatric patients, 129 women and 71 men, were given recommendations by a four-person staff of their receiving psychodynamic therapy (PDT; 47 women, 17 men), cognitive psychotherapy (CPT; 19 women, 5 men) or cognitive behavioral therapy (CBT; 34 women, 20 men), or of their having no psychotherapy (NPT; 29 women, 29 men). The staff knew the ICD-10 diagnoses but made its judgments p

This paper describes how attribute grammars can be used to generate state diagrams from a program written in a simple transition language and then drawn using a graph drawing tool. We use an extended form of attribute grammars, RAGs, which permits attributes to be references to nodes in the syntax tree. The directed graph defined by the program is constructed in the AST by linking together nodes v

OBJECTIVE: To determine the extent to which Doppler ultrasound examination contributes to a correct specific diagnosis of a pelvic mass when the preliminary diagnosis is based on subjective evaluation of the gray-scale ultrasound image (pattern recognition). METHODS: In 173 consecutive cases, women scheduled for surgery because of a pelvic mass judged clinically to be of adnexal origin underwent p

The protonation status of key residues and bound ligands are often important for the function of a protein. Unfortunately, protons are not discerned in normal protein crystal structures, so their positions have to be determined by more indirect methods. We show that the recently developed quantum refinement method can be used to determine the position of protons in crystal structures. By replacing

Popular Abstract in Swedish Avhandlingen behandlar den kristna minoriteten Old Order Amish i USA ur ett ecklesiologiskt perspektiv. Genom att dels använda centrala begrepp som utgår från den undersökta gruppens egen religiösa vokabulär, dels några av de angreppssätt som är förhärskande inom det kyrkovetenskapliga studiet, framträder en fördjupad bild av amishfolkets insida. Hur uppfattar amish siThe thesis focuses on the way the Amish view their life and actions as Christians. With its basis in first-hand observations from the settlements of Dover (DE) and Lancaster (PA) the inquiry describes, analyzes and interprets the ecclesiastical life of the Old Order Amish from an ecclesiological viewpoint. Utilizing a specific model of analysis the dissertation examines the institutions (church/f