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Dorsal anterior cingulate cortex activity during cognitive challenge in social anxiety disorder

Background: Social anxiety disorder (SAD) is associated with aberrant emotional information processing while little is known about non-emotional cognitive processing biases. The dorsal anterior cingulate cortex (dACC) has been implicated in SAD neuropathology and is activated both by emotional and non-affective cognitive challenges like the Multisource Interference Task (MSIT). Methods: Here, we u

An auditory processing advantage enables communication in less complex social settings : Signs of an extreme female brain in children and adolescents being assessed for Autism Spectrum Disorders

Background: The underlying factors of the male predominance in Autism Spectrum Disorders (ASD) are largely unknown, although a female advantage in social communication has been pointed out as a potential factor. Recently, attention has been given to ASD as a sensory processing disorder, focusing on the audio-visual temporal processing paramount for the development of communication. In ASD, a devia

Vargkrigardiplomati - En kvalitativ teorikonsumerande fallstudie om Kinas diplomatiska förfarande

To commence, this is a qualitative case study about China and its diplomatic ties to the outside world, particularly Sweden. The thesis examines and illustrates an aggressive and coercive form of diplomacy utilized extensively by Chinese diplomats around the world; called “wolf warrior diplomacy”. Fundamentally, this diplomacy is a comparatively new phenomenon – or so it seems. Popular application

Vad är problemet med etnisk boendesegregation? En poststrukturalistisk policyanalys av Stefan Löfvens (2021) och Ulf Kristerssons (2022) budgetpropositioner

Residential segregation is a geographical expression of inequality. The aim of this thesis is to examine how segregation has been represented as a problem in Swedish politics in recent years. My objects of study are two budget proposals, by Stefan Löfven (S) (2021) and Ulf Kristersson (M) (2022) respectively. I have made a poststructural policy analysis using Carol Bacchis method “What's the p

Kuwait, Irak och Syrien. Vad har lett till en så konfliktdrabbad region?

Arbetet ämnar att förklara och förstå skillnader och likheter i orsakerna till konflikter i regionen Syrien, Irak och Kuwait under de senaste tre decennierna. Genom återkommande faktorer vid alla faktorer generaliseras sedan dessa orsaksförklaringar mer generellt för att kunna appliceras på andra regioner runt om i världen. Arbetet kommer att analysera konflikterna utifrån neoliberal institutional

An Overview of Systematic Reviews and Meta-Analyses on the Effect of Medication Interventions Targeting Polypharmacy for Frail Older Adults

Frailty refers to the lack of resilience and a reduction in a person’s ability to recover following a health problem, and it is increasingly becoming a challenging aspect of ageing populations.Many older adults are exposed to polypharmacy; i.e., they continue to be on medications without timely re-evaluation. Medication reviews have proven successful in managing polypharmacy in the general populat

The use of multi-zone modelling for tunnel fires

This paper introduces the use of a multi-zone modelling approach for analysing smoke spread in tunnels. The approach suggested in this paper is based on an existing model, i.e., the Multi-Zone Fire model developed for large spaces. The Multi-Zone Fire model has been adapted and modified for tunnel fire scenarios by including features that consider longitudinal ventilation flow, tunnel gradient and

Large-bias spectroscopy of Yu-Shiba-Rusinov states in a double quantum dot

We have performed tunnel transport spectroscopy on a quantum dot (QD) molecule proximitized by a superconducting contact. In such a system, the scattering between QD spins and Bogoliubov quasiparticles leads to the formation of Yu-Shiba-Rusinov (YSR) states within the superconducting gap. In this work, we investigate interactions appearing when one- and two-electron spin states in a double-QD ener

SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD

SPATA2 mediates the recruitment of CYLD to immune receptor complexes by bridging the interaction of CYLD with the linear ubiquitylation assembly complex (LUBAC) component HOIP. Whether SPATA2 exhibits functions independently of CYLD is unclear. Here, we show that, while Cyld−/− and Spata2−/− mice are viable, double mutants exhibit highly penetrant perinatal lethality, indicating independent functi