Road agencies set quantitative targets and adopt related road safety strategics in accordance with each agency's priorities and available resources. Benefit-cost analyses are carried out to support the decision-making process, and alternative measures are ranked according to their expected benefits and benefit-cost ratios, calculated with a safety performance function (SPF) and crash modification

Attosecond extreme ultraviolet light pulses have the potential to resolve the ultrafast electron dynamics that govern basic properties of atoms, molecules, and solids. Here we present three different interferometric pump-probe methods aiming to access not only the temporal dynamics, but also state specific phase information after excitation/ionization using attosecond pulses.

The recently demonstrated momentum shearing interferometry technique, aimed at recovering phase information about electronic wave packets (EWP) will be presented. Possibilities to improve this technique will be discussed.

Meniscectomy is recognized as an important risk factor for the development of knee osteoarthritis (OA), a disease that traditionally has been considered as a simple "wear and tear" phenomenon. However, despite numerous reports, little evidence has been presented that a limited meniscal resection, compared with a more extensive resection, reduces the risk of OA by preserving meniscal function. Why?

This chapter argues against the claim that morally ignorant wrongdoers are open to blame only if they are culpable for their ignorance, and argues against a version of skepticism about moral responsibility that depends on this claim being true. On the view defended, the attitudes involved in blame are typically responses to the features of an action that make it objectionable or unjustifiable from

Purpose: To empirically explore and describe the process and practices of managing product returns in Internet retailing.Design/methodology/approach: A multiple case study involving twelve e-commerce firms and four logistics service providers. Using semi-structured interviews, documentation, and observations as an integrative data collection approach to gain a comprehensive managerial and operatio

BACKGROUND: Chronic kidney disease (CKD) is associated with accelerated cardiovascular disease and heart failure. Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has been associated with a worse phenotype amongst patients with established heart failure and in patients with progression of their renal disease. The association of a cardiac functional d

CONTEXT: Viral/bacterial infection is proposed as a trigger for the autoimmune thyroid diseases (AITD): Graves' disease (GD) and Hashimoto's thyroiditis (HT). Previous studies in European Caucasian AITD subjects found higher birth rates in the autumn/winter, suggesting those born in the autumn/winter experience increased viral/bacterial exposure after birth, impacting upon immune system developmen

We measured the frequency chirp rate of harmonics 13 to 23 in argon by cross-correlation with a short femtosecond probe pulse. We directly measured the negative chirp due to the atomic dipole phase and demonstrated that an additional chirp on the pump pulse was transferred to the qth harmonic as q times the fundamental chirp.

The resistance-in-series model, used to describe the mass transfer through a membrane in pervaporation for binary systems, has been extended to include ternary and multi-component mixtures of different organic and inorganic compounds in aqueous solutions. The new model was used in a simulation including the membrane characteristics and the geometry of the pervaporation. Thus, the influence of proc

Objectives: This study sought to examine the relationship between temperature at reperfusion and infarct size. Background: Hypothermia consistently reduces infarct size when administered prior to reperfusion in animal studies, however, clinical results have been inconsistent. Methods: We performed a patient-level pooled analysis from six randomized control trials of endovascular cooling during pri

Pancreas transplantation is a successful treatment for a selected group of people with type 1 diabetes. Continued insulin production can decrease over time and identifying predictors of long-term graft function is key to improving survival. The aim of this study was to screen subjects for variation in the Caveolin-1 gene (Cav1), previously shown to correlate with long-term kidney transplant functi