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Alzheimer's disease (AD) presents complex challenges due to its multifactorial nature, poorly understood etiology, and late detection. The mechanisms through which genetic and modifiable risk factors influence disease susceptibility are under intense investigation, with APOE being the major genetic risk factor for late onset AD. Yet the impact of unique risk factors on brain networks is difficult

Background: International research demonstrates an association between arts and culture activities and health and wellbeing. A similar association exists for sports event attendance and health. The aim of this study was to investigate associations between arts and culture engagement and attending sports events during the past year and self-rated health (SRH). Methods: A cross-sectional study. A pu

Aim: We examined the association of exposure to a pesticide mixture with respiratory and allergic outcomes among farmworkers from Costa Rica. Methods: We conducted a cross-sectional study of 299 farmworkers between May and August 2016. We collected information on sociodemographic factors, pesticide use, and the presence of respiratory and allergic symptoms during the last 12 months via questionnai

The currently most promising approach for reducing CO2 emissions of the global steel production is reducing iron ore in shaft furnaces with (green) hydrogen instead of blast furnaces. Unlike to the liquid iron produced in blast furnaces, the direct reduced iron produced in this route (green iron) exists in a solid state and can be transported at reasonable costs over long distances. This allows fo

Objective: Ultrasound (US) images during a muscle contraction can be decoded into individual motor unit (MU) activity, i.e., trains of neural discharges from the spinal cord. However, current decoding algorithms assume a stationary mixing matrix, i.e. equal mechanical twitches at each discharge. This study aimed to investigate the accuracy of these approaches in non-ideal conditions when the mecha

The critical soil moisture threshold (SMth) of plant water stress distinguishes whether vegetation is in an energy-limited or water-limited regime. Accurate quantification of SMth for grasslands holds significant implications for drought monitoring and efficient grassland management. However, our understanding of SMth within global grasslands remains limited. In this study, we investigated the rel

The technique to perform adnexectomy for adnexal masses has shifted over the last decades, from open surgery towards minimally invasive approaches. At the same time caution is warranted to prevent perioperative intra-abdominal spilling of cyst content which can be a challenge especially for very large masses. vNOTES (vaginal Natural Orifice Transluminal Endoscopic Surgery) combines a vaginal appro

Background: Transcatheter aortic valve replacement (TAVR) is the most common treatment in patients with symptomatic severe aortic stenosis (AS). As concomitant coronary artery disease is common in AS patients, access to the coronary arteries following TAVR is of increasing importance. Objectives: This study evaluated the incidence and risk factors for unplanned coronary angiography following TAVR

Cathodoluminescence (CL) in the scanning electron microscope (SEM) or the scanning transmission electron microscope (STEM) is a very useful tool for the characterization of low-dimensional semiconductor structures. To obtain spatial resolution, the SEM/STEM provides a highly focused electron beam that can be positioned at specific sites to obtain spot mode spectra. The beam can also be scanned ove

The work was commissioned by Västerås Sinfonietta. Opus 122. The piece has been performed at two concerts in Paris and one concert in Wroclaw, Poland, with the Insula Orchestra conducted by Laurence Equilbey. It is also scheduled to be performed by the Swedish Chamber Orchestra in March 2025. Instrumentation: orchestra.

Aims/hypothesis: The aim of this work was to examine the impact of hypoglycaemia on daily functioning among adults with type 1 diabetes or insulin-treated type 2 diabetes, using the novel Hypo-METRICS app. Methods: For 70 consecutive days, 594 adults (type 1 diabetes, n=274; type 2 diabetes, n=320) completed brief morning and evening Hypo-METRICS ‘check-ins’ about their experienced hypoglycaemia a

Purpose: Due to limited data on treatment-related risk factors associated with esophageal stricture in childhood cancer survivors, this study aimed to assess such factors in long-term survivors. Methods: A case-cohort study was conducted involving 36 cases of five-year childhood cancer survivors with esophageal stricture and a sub-cohort of 540 survivors diagnosed with cancer in 1970–2007 as ident

The polar regions are increasingly at the center of attention as the hot spots of climate crisis as well as tourism development. The recent IPCC reports highlight several climate change risks for the rather carbon-intensive and weather-based/dependent polar tourism industry in the Arctic and the Antarctic. This study presents the scholarly state-of-knowledge on tourism and climate change in the po

Alkaliphilic microorganisms are one option for the treatment of cyanide-polluted wastewater. This study reports the degradation of cyanide from simulated gold mine wastewater using alkaliphilic microbial consortia harvested from a soda lake, Lake Chitu, Ethiopia. A novel aerobic-anoxic integrated treatment setup was established for the treatment process. Colorimetry was used to measure residual cy

Commissioned by the Florin Harp Trio. Instrumentation: oboe, cello, harp. Several concerts are planned for spring 2025.

Background: People with chronic inflammatory arthritis (IA) often have a reduced work ability. Consequently, they are at high risk of losing their jobs and being permanently excluded from the labor market. Therefore, we developed a new context-specific vocational rehabilitation intervention for people with IA based on the Medical Research Council’s framework for complex interventions. This interve

Do student teachers benefit from contact with research, as required in our national teacher education curriculum? This paper describes the experiences of two pre-service teachers, who learned about common challenges encountered in the intersection between mathematics and physics. After a literature survey, they decided to try out a few questions with second-year high-school students (age 17). One

Middle-aged adults engaging in unhealthy lifestyle behaviors are at higher risk of chronic diseases. However, little is known about the co-occurrence of these behaviors and their determinants. This cohort study examined the co-occurrence of unhealthy lifestyle behaviors (alcohol consumption, diet, physical inactivity, and smoking) in 30,154 middle-aged adults and their associations with sociodemog

Solid-state NMR has great potential for investigating molecular structure, dynamics, and organization of the stratum corneum, the outer 10–20 μm of the skin, but is hampered by the unfeasibility of isotope labelling as generally required to reach sufficient signal-to-noise ratio for the more informative multidimensional NMR techniques. In this preliminary study of pig stratum corneum at 35 °C and

This paper addresses the role of incumbent firms in driving transitions that entail multiple sectors, conditioned by multiple regimes. We analyse the case ‘HYBRIT’, a radical innovation venture championed by three incumbents from the steel and energy regimes. We investigate what conditions the incumbents’ agency and how they enacted their agency targeting restructuring of the regime elements–actor