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On the Formation of Necks at Crack Tips under Plane Stress Conditions.

The conditions for necking are well defined through the theory of Hill [1]. These conditions are applied to elasto plastic linearly hardening Tresca.and v Mises materials for different hardening characteristics. The results suggest that necking developes for all hardening materials. Below a certain hardening the stresses normal to the necking region and just outside it decrease during the necking

International Law and Violence against Women: Europe and the Istanbul Convention

This book offers an in-depth and critical analysis of the Istanbul Convention, along with discussions on its impact and implications.The work highlights the place of the Convention in the landscape of international law and policies on violence against women and equality. The authors argue that the Convention with its emphasis on integrated and comprehensive policies has an important role in promot

Due Diligence versus Positive Obligations: Critical Reflections on the Council of Europe Convention on Violence against Women

Article 5 of the Council of Europe Convention on Preventing and Combating Violence against Women and Domestic Violence (the Istanbul Convention) enshrines the standard of due diligence to frame states’ obligations. In the existing literature in the area of violence against women, the standard of due diligence has been uncritically endorsed; the reason being that it has played a crucial role in the

Fault, Knowledge and Risk within the Framework of Positive Obligations under the European Convention on Human Rights

The European Court of Human Rights has consistently reiterated that positive obligations under the European Convention on Human Rights arise when state authorities knew or ought to have known about risk of harm. This article attempts to describe and assess the role of state knowledge in the framework of positive obligations, and to situate the Court’s approach to knowledge about risk within an int

Dietary Polyphenols in the Aetiology of Crohn's Disease and Ulcerative Colitis-A Multicenter European Prospective Cohort Study (EPIC)

BACKGROUND: Oxidative stress may be involved in the aetiology of inflammatory bowel disease and whether dietary polyphenols, which possess antioxidants properties, prevent its development is unknown.METHODS: A total of 401,326 men and women aged 20 to 80 years from 8 countries were recruited between 1991 and 1998 and at baseline completed validated food frequency questionnaires. Dietary polyphenol

Finding Gender at the Intersection of Family and Field : Family Presences in Sweden

Gender influences how researchers engage with the field (Porter & Schänzel, 2018). Departing from this proposition, this chapter offers reflections on gender from masculine vantages in the context of a qualitative research project investigating tourism enterprising in southern Sweden. Tourism enterprising is an important aspect of tourism development. Focusing on personal experiences associate

GEANT4 Spectroscopy of Heavy and Superheavy Atomic Nuclei: Element 115

A high-resolution alpha, electron, X-ray and gamma-ray coincidence experiment was conducted at the GSI Helmholtzzentrum für Schwerionenforschung GmbH in Darmstadt, Germany. It aimed to identify and study alpha-decay chains of isotopes of element Z=115. Experimental data, including the 30 identified chains, were analyzed self-consistently with a virtually constructed spectroscopic set-up using GEAN

‘You are where you shop’: Examining stereotypes about town center shoppers

The future role of the town center as a retail hub is uncertain. Despite being a historical meeting place, town centers have been struggling for decades to attract customers and retain retailers after the development of out-of-town centers and advancement of online shopping. Previous retail research has mostly used rational explanations and strategies like improved access, pricing, and retail mix

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Dupuytren's disease is a hereditary fibroproliferative disease commonly affecting the palmar fascia of the hand, which results in progressive and irreversibly fixed flexion contractures of the hand. It may occur in the sole of the foot or in the penis. Generally, treatment has been up against a high frequency of complications and recurrence, but promising results are reported from less invasive tr

Low-Dose Oral Ketamine for Procedural Analgesia in Pediatric Cancer Patients Undergoing Lumbar Puncture at a Resource-Limited Cancer Hospital in India

Aim: The aim of this study was to evaluate the therapeutic efficacy and safety profile of orally administered low-dose ketamine for procedural pain management in pediatric cancer patients undergoing lumbar puncture (LP) in a resource-limited hospital setting. Methods: Patients between 4 and 15 years of age, with leukemia, undergoing LP were asked to participate. The study was designed as a two-a

New concepts for transdermal delivery of oxygen based on catalase biochemical reactions studied by oxygen electrode amperometry

The development of formulation concepts for improved skin tissue oxygenation, including methods for measuring oxygen (O2) transport across biological barriers, are important research topics with respect to all processes that are affected by the O2 concentration, such as radiation therapy in oncology treatments, wound healing, and the general health status of skin. In this work we approach this top

Cancer Treatment and End-of-Life Care

AIM: To study to what extent tumor-specific treatment (chemo- or radiotherapy) was given during the last 30 days in life and to examine how many of the patients were referred to a specialized palliative care unit (PCU), at a low-resource governmental hospital in India.PATIENTS AND METHODS: Medical records of adult cancer patients deceased between April 1 and May 31 in 2016, and pediatric cancer pa

Primary gastric non-Hodgkin's lymphoma. A retrospective clinico-pathological study

Prognostic factors and treatment results were analysed in 72 consecutive patients with primary gastric lymphoma treated between 1970 and 1985. There were 37 patients in stage IE, 17 in IIE, 3 in IIES and 15 in stage IV. Histopathological re-evaluation and classification according to the TNM system were performed. We found that disseminated disease (stage IV), serosal penetration (T3), involvement

Chromosome aberrations in psoriatic patients treated with arsenic

A significantly increased frequency of chromosomal aberrations was found in lymphocytes from eight psoriatic patients previously treated with arsenic than in lymphocytes from eight psoriatics with no such previous treatment. In most patients the arsenic therapy was discontinued more than 15 years ago. In the arsenic-treated group a statistically significant heterogeneity was found with respect to

Early Metabolic Flare in Squamous Cell Carcinoma after Chemotherapy is a Marker of Treatment Sensitivity In Vitro

PURPOSE: Early metabolic response with a decrease in glucose demand after cytotoxic treatment has been reported to precede tumor volume shrinkage. However, preclinical studies report of a very early rise in metabolism, a flare, following treatment. To elucidate these observations, we performed an experimental study on early metabolic response with sequential analysis of metabolic changes. METHODS: