The outcome of 9 years of consecutive patch testing with 4,4'-diaminodiphenylmethane and 4,4'-diphenylmethane diisocyanate.
Background: Two outbreaks of allergic contact dermatitis caused by isocyanates at two companies in southern Sweden initiated a research project focusing on contact allergy to isocyanates. Within the project, there was an interest in determining how often contact allergy to the most common isocyanate, diphenylmethane-4,4'-diisocyanate (4,4'-MDI), occurred. Objectives: To determine and compare the
