Here we define a function of metastasis-associated protein 1 (MTA1), a presumed corepressor of estrogen receptor alpha (ER alpha), as a transcriptional activator of Breast Cancer Amplified Sequence 3 (BCAS3), a gene amplified and overexpressed in breast cancers. We identified BCAS3 as a MTA1 chromatin target in a functional genomic screen. MTA1 stimulation of BCAS3 transcription required ERa and i

In their seminal work, Im et al. (1997, 2003) suggested that time series for several cross-sectional units could be used to increase the power of the Dickey-Fuller unit root test. They argued that when cross-sectional correlation is a problem that can be modelled by a time-specific factor, demeaning across the cross-sectional units can solve the problem. In this study, this proposition is proven v

Sheet-metal forming involves a complex strain distribution over the part. The strains consist of tension, compression, and a mix of both. A geometry has been developed, the X-Die, in order to gain insight into the strain behavior of different materials. The X-Die enables strain paths far into the tension/compression region, thus creating the possibility to extend the experimental base both for def

The demand for information and transparency from corporations has increased over the last few years. Today, there are other information dissemination channels besides annual financial statements. One important channel is the Internet. The aim of this study is to explain the extent and content of social disclosure information on corporations' websites. The empirical data in this study is based on a

Background: Involuntary migration and adaptation to a new cultural environment is known to be a factor of psychological stress. Primary Health Care Nurses (PHCNs) frequently interact with refugee families as migrant health needs are mainly managed within Primary Health Care. Aim: To describe the health of the involuntary migrated family in transition as conceptualized by Swedish PHCNs. Method: Thi

Like many animals migrating through the oceans, sea turtles face difficult navigational tasks when they have to reach distant, specific sites. The paradigmatic case of Brazilian green turtles (Chelonia mydas), which nest on the tiny Ascension Island in the middle of the Atlantic Ocean, has often been the subject of hypotheses concerning their navigational mechanisms. To investigate their nature, w

Objectives: The purpose of the study is to quantitatively analyze the role of health insurance in the determinants of catastrophic health payments in a low-income country setting. Methods: The study uses the most recent publicly available household level data from Zambia collected in 1998 containing detailed information on health care utilization and spending and on other key individual, household

In this paper we describe an image-based approach to finding location-based information from camera-equipped mobile devices. We introduce a point-by-photograph paradigm, where users can specify a location simply by taking pictures. Our technique uses content-based image retrieval methods to search the web or other databases for matching images and their source pages to find relevant location-based

We use density functional theory to investigate how the presence of polymers influence the interactions between adsorbing or nonadsorbing flat surfaces, forming a slit geometry. The study is primarily made under "restricted equilibrium" conditions, i.e., below a threshold separation, the chains are allowed to equilibrate conformationally between the surfaces, but they are unable to diffuse into or

There are emerging data to suggest a role for genetic factors in the pathogenesis of multiple myeloma (MM). Based on small numbers, certain solid tumors have been reported to occur more frequently among blood relatives of patients with MM. Using population-based data, we assessed risks for hematologic malignancies, monoclonal gammopathy of undetermined significance (MGUS), and solid tumors among f

A project on electronic publishing of doctoral dissertations in fulltext started in 1998 at the Lund University Library. Dissertations that consist of a number of articles that have already been published in or submitted to scholarly journals posed a potentional problem with regard to copyright questions. In order to solve this problem, the commersial publishers were approached with a request for

Standardized intra-abdominal hemorrhage was induced in 7 anesthetized pigs. The resulting hypovolemic shock was treated with pneumatic anti-shock garment (PASG) followed by intra-aortic balloon occlusion. The effects of this treatment on circulation, lung mechanics and gas exchange were studied. Hemorrhage was induced by pulling out sutures introduced in the inferior caval vein. We found that the

A lifted turbulent H-2/N-2 flame in a vitiated co-flow is studied using Large Eddy Simulation together with a closure based on perfectly stirred reactors. A part of the closure, chemical look-up tables, are generated to close the filtered temperature equations and to compute local radical concentrations throughout the computational domain. The approach has been used to simulate a lifted turbulent

Bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) is widely used in the management of patients with osteoporosis. Factors, which are specific to machine or to operator, can influence the accuracy and precision of BMD estimations. We studied the effect of leg rotation by 10 degrees either internally or externally from the standard position in a group of 50 women (average

We offer an alternative palaeoenvironmental interpretation of oxygen-isotope data obtained on two early-Holocene stalagmite records from caves in the Scandes Mountains of northern Sweden (Korallgrottan and Labrintgrottan), and the well-known Soylegrotta (Norway) SG93 record with which they are compared, that differs in several respects from that proposed by the authors. Contrary to viewing these a

In this paper, a new approach for on-line monitoring and detection of abnormal readily biodegradable substrate (SS) and slowly biodegradable substrate (XS) concentrations, for example due to input of toxic loads from the sewer, or due to influent substrate shock load, is proposed. Considering that measurements of SS and XS concentrations are not available in real wastewater treatment plants, the S

We present high spatial resolution ion-microprobe U-Th-Pb geochronology and rare earth element (REE) data combined with cathodoluminescence (CL) and back-scattered electron (BSE) imaging for complex zircons in incipient charnockites from Sondrum, SW Sweden. Examination of closely paired samples across the dehydration zone demonstrates that incipient charnockite formation at Sondrum is a zircon-for